PMID- 31902023
OWN - NLM
STAT- MEDLINE
DCOM- 20210309
LR  - 20210525
IS  - 1618-7601 (Electronic)
IS  - 1618-7598 (Linking)
VI  - 21
IP  - 4
DP  - 2020 Jun
TI  - A vision 'bolt-on' increases the responsiveness of EQ-5D: preliminary evidence 
      from a study of cataract surgery.
PG  - 501-511
LID - 10.1007/s10198-019-01156-w [doi]
AB  - OBJECTIVES: (1) To evaluate the effect of adding a vision dimension ('bolt-on') 
      to the 5-level EQ-5D (EQ-5D-5L) and 3-level EQ-5D (EQ-5D-3L) on their 
      responsiveness, and (2) to compare the responsiveness of a vision 'bolt-on' 
      EQ-5D-3L (EQ-5D-3L + V) with SF-6D and Health Utilities Index Mark 3 (HUI3) to 
      the benefit of cataract surgery. METHODS: Sixty-three patients were assessed 
      before and after their cataract surgery using the EQ-5D-3L, EQ-5D-5L, SF-6D, 
      HUI3, as well as a 3-level and a 5-level vision dimension. Preference-based 
      indices were calculated using available value sets for EQ-5D-3L, EQ-5D-3L + V, 
      EQ-5D-5L, SF-6D, and HUI3, and non-preference-based indices were calculated using 
      the sum-score method for EQ-5D-5L and EQ-5D-5L + V (vision bolt-on EQ-5D-5L). 
      Responsiveness was assessed using the standardized response mean (SRM) and 
      F-statistic. RESULTS: Among preference-based indices, mean changes from pre to 
      post-surgery in EQ-5D-3L + V and EQ-5D-3L indices were 0.031 and 0.018, 
      respectively. The mean changes for EQ-5D-5L, SF-6D and HUI3 indices were 0.020, 
      0.012 and 0.105, respectively. The SRM (F-statistic) for EQ-5D-3L + V and 
      EQ-5D-3L indices were 0.458 (13.2) and 0.098 (0.6), respectively. The 
      responsiveness of EQ-5D-3L + V was better than EQ-5D-5L, SF-6D; the 
      responsiveness of HUI3 was better than all other measures. Using 
      non-preference-based indices, mean change for EQ-5D-5L + V and EQ-5D-5L were 
      0.067 and 0.017, respectively. The corresponding SRM (F-statistic) were 0.709 
      (31.7) and 0.295 (5.4). CONCLUSIONS: Preliminary evidence from our study suggests 
      that a vision 'bolt-on' may increase the responsiveness of EQ-5D-3L and EQ-5D-5L 
      to change in health outcomes experienced by patients undergoing cataract surgery. 
      In absence of the preference-based vision bolt-on EQ-5D-5L index, HUI3 was the 
      most responsive measure.
FAU - Gandhi, Mihir
AU  - Gandhi M
AUID- ORCID: 0000-0002-8902-2710
AD  - Department of Biostatistics, Singapore Clinical Research Institute, #02-01, 31 
      Biopolis Way, Singapore, Singapore.
AD  - Centre for Quantitative Medicine, Duke-NUS Medical School, 8 College Road, 
      Singapore, Singapore.
AD  - Tampere Center for Child Health Research, Tampere University, Arvo-building, 
      Tampere, Finland.
FAU - Ang, Marcus
AU  - Ang M
AUID- ORCID: 0000-0003-3022-0795
AD  - Department of Ophthalmology, Singapore National Eye Centre, 11 Third Hospital 
      Ave, Singapore, Singapore.
AD  - Ophthalmology and Visual Sciences Department, Duke-NUS Medical School, 8 College 
      Road, Singapore, Singapore.
FAU - Teo, Kelvin
AU  - Teo K
AUID- ORCID: 0000-0002-7458-7081
AD  - Department of Ophthalmology, Singapore National Eye Centre, 11 Third Hospital 
      Ave, Singapore, Singapore.
FAU - Wong, Chee Wai
AU  - Wong CW
AUID- ORCID: 0000-0002-0935-2016
AD  - Department of Ophthalmology, Singapore National Eye Centre, 11 Third Hospital 
      Ave, Singapore, Singapore.
FAU - Wei, Yvonne Chung-Hsi
AU  - Wei YC
AUID- ORCID: 0000-0002-5515-4029
AD  - Department of Ophthalmology, Singapore National Eye Centre, 11 Third Hospital 
      Ave, Singapore, Singapore.
FAU - Tan, Rachel Lee-Yin
AU  - Tan RL
AUID- ORCID: 0000-0002-4610-1195
AD  - Saw Swee Hock School of Public Health, National University of Singapore, 12 
      Science Drive 2, Singapore, Singapore.
FAU - Janssen, Mathieu F
AU  - Janssen MF
AUID- ORCID: 0000-0001-6602-6949
AD  - Section Medical Psychology and Psychotherapy, Department of Psychiatry, Erasmus 
      MC, Rotterdam, The Netherlands.
FAU - Luo, Nan
AU  - Luo N
AUID- ORCID: 0000-0001-7980-6979
AD  - Saw Swee Hock School of Public Health, National University of Singapore, 12 
      Science Drive 2, Singapore, Singapore. ephln@nus.edu.sg.
LA  - eng
GR  - EQ Project 2016310/EuroQol Research Foundation/
PT  - Journal Article
DEP - 20200104
PL  - Germany
TA  - Eur J Health Econ
JT  - The European journal of health economics : HEPAC : health economics in prevention 
      and care
JID - 101134867
RN  - 0 (Morpholines)
RN  - 14343-30-7 (RE 102)
SB  - IM
MH  - Aged
MH  - Cataract Extraction/*economics
MH  - Cost-Benefit Analysis/*methods
MH  - Female
MH  - Health Status
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Morpholines
MH  - *Patient Preference
MH  - Prospective Studies
MH  - Psychometrics
MH  - Quality of Life
MH  - Reproducibility of Results
MH  - Surveys and Questionnaires/*standards
MH  - *Visual Acuity
OTO - NOTNLM
OT  - Bolt-on
OT  - Cataract
OT  - EQ-5D
OT  - Responsiveness
OT  - Vision
EDAT- 2020/01/07 06:00
MHDA- 2021/03/10 06:00
CRDT- 2020/01/06 06:00
PHST- 2019/06/05 00:00 [received]
PHST- 2019/12/20 00:00 [accepted]
PHST- 2020/01/07 06:00 [pubmed]
PHST- 2021/03/10 06:00 [medline]
PHST- 2020/01/06 06:00 [entrez]
AID - 10.1007/s10198-019-01156-w [pii]
AID - 10.1007/s10198-019-01156-w [doi]
PST - ppublish
SO  - Eur J Health Econ. 2020 Jun;21(4):501-511. doi: 10.1007/s10198-019-01156-w. Epub 
      2020 Jan 4.