PMID- 31902269
OWN - NLM
STAT- Publisher
LR  - 20240227
IS  - 1743-8942 (Electronic)
IS  - 0167-482X (Linking)
DP  - 2020 Jan 6
TI  - Depressive symptoms at postpartum are associated with those at the second 
      trimester of pregnancy and the antioxidant activity immediately after delivery.
PG  - 1-7
LID - 10.1080/0167482X.2019.1709817 [doi]
AB  - Objective: This study aimed to investigate whether depressive symptoms at 
      postpartum are associated with oxidative stress and antioxidant activity, as well 
      as the symptoms during pregnancy.Methods: This longitudinal study enrolled 84 
      women in their second trimester of pregnancy. Their depressive symptoms were 
      assessed using Edinburgh postnatal depression scale (EPDS), and their oxidative 
      stress and antioxidant activity were assessed using reactive oxygen 
      metabolites/8-hydroxy-2'-deoxyguanosine and biological antioxidant potential 
      (BAP) at around 26 and 36 weeks (time points 1 and 2) of gestation, and 3-6 days 
      and 1 month (time points 3 and 4) postpartum. We evaluated the associations 
      between EPDS at time point 4 and various parameters at the other time 
      points.Results: Multiple regression analysis revealed that EPDS at time point 1 
      (adjusted odds ratio: 1.06 per 0.1 point increase; 95% confidence interval [CI]: 
      1.03-1.11) and BAP at time point 3 (adjusted odds ratio: 0.93 per 10 mumol/L 
      increase; 95% CI: 0.87-0.97) were independent predictors of EPDS at time point 
      4.Conclusion: Depressive symptoms at the second trimester of pregnancy and the 
      antioxidant activity immediately after delivery could predict postpartum 
      depression. TRIAL REGISTRATION: UMIN-CTR UMIN000022367.
FAU - Hirose, Asuka
AU  - Hirose A
AUID- ORCID: 0000-0003-2731-4790
AD  - Department of Obstetrics and Gynecology, Tokyo Medical and Dental University, 
      Tokyo, Japan.
AD  - Department of Women's Health, Tokyo Medical and Dental University, Tokyo, Japan.
FAU - Terauchi, Masakazu
AU  - Terauchi M
AUID- ORCID: 0000-0001-5577-0094
AD  - Department of Women's Health, Tokyo Medical and Dental University, Tokyo, Japan.
FAU - Odai, Tamami
AU  - Odai T
AD  - Department of Obstetrics and Gynecology, Tokyo Medical and Dental University, 
      Tokyo, Japan.
FAU - Kato, Kiyoko
AU  - Kato K
AD  - Department of Women's Health, Tokyo Medical and Dental University, Tokyo, Japan.
FAU - Miyasaka, Naoyuki
AU  - Miyasaka N
AUID- ORCID: 0000-0002-4713-8352
AD  - Department of Obstetrics and Gynecology, Tokyo Medical and Dental University, 
      Tokyo, Japan.
LA  - eng
PT  - Journal Article
DEP - 20200106
PL  - England
TA  - J Psychosom Obstet Gynaecol
JT  - Journal of psychosomatic obstetrics and gynaecology
JID - 8308648
SB  - IM
OTO - NOTNLM
OT  - 8-OHdG
OT  - BAP
OT  - Edinburgh postnatal depression scale
OT  - Oxidative stress
OT  - antioxidant activity
OT  - d-ROM
EDAT- 2020/01/07 06:00
MHDA- 2020/01/07 06:00
CRDT- 2020/01/07 06:00
PHST- 2020/01/07 06:00 [entrez]
PHST- 2020/01/07 06:00 [pubmed]
PHST- 2020/01/07 06:00 [medline]
AID - 10.1080/0167482X.2019.1709817 [doi]
PST - aheadofprint
SO  - J Psychosom Obstet Gynaecol. 2020 Jan 6:1-7. doi: 10.1080/0167482X.2019.1709817.