PMID- 3190327 OWN - NLM STAT- MEDLINE DCOM- 19881206 LR - 20190628 IS - 0003-4975 (Print) IS - 0003-4975 (Linking) VI - 46 IP - 5 DP - 1988 Nov TI - The Ionescu-Shiley pericardial valve: results in 473 patients. PG - 536-41 AB - From January 1, 1980, through December 31, 1985, 473 patients underwent valve replacement with an Ionescu-Shiley valve. Overall hospital mortality was 7.8%. Major associated procedures and preoperative New York Heart Association (NYHA) Classes IV and V influenced hospital mortality significantly. The mean follow-up was 2.6 +/- 1.3 years. Late mortality was 5.9%. Overall actuarial survival was 81% at 5 years. A chief cause of reoperation was cusp rupture of a mitral prosthesis in 5 patients (all after aortic and mitral valve replacement). The overall actuarial reoperation-free incidence was 93% at 5 years. Thromboembolic (TB) phenomena occurred at a linear incidence of 1.4 +/- 0.3% per patient-year or an actuarial thromboembolism-free incidence of 92% at 5 years. Univariate and multivariate analyses showed that postoperative NYHA Class, rhythm at follow-up, and anticoagulant therapy significantly influenced the incidence of TE phenomena. FAU - Daenen, W AU - Daenen W AD - Department of Cardiovascular Surgery, University Hospital Gasthuisberg, Leuven, Belgium. FAU - Noyez, L AU - Noyez L FAU - Lesaffre, E AU - Lesaffre E FAU - Goffin, Y AU - Goffin Y FAU - Stalpaert, G AU - Stalpaert G LA - eng PT - Journal Article PL - Netherlands TA - Ann Thorac Surg JT - The Annals of thoracic surgery JID - 15030100R SB - IM MH - Aged MH - Aortic Valve MH - *Bioprosthesis/mortality MH - Female MH - *Heart Valve Prosthesis/mortality MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve MH - Postoperative Complications MH - Prosthesis Failure MH - Thromboembolism/etiology MH - Tricuspid Valve EDAT- 1988/11/01 00:00 MHDA- 1988/11/01 00:01 CRDT- 1988/11/01 00:00 PHST- 1988/11/01 00:00 [pubmed] PHST- 1988/11/01 00:01 [medline] PHST- 1988/11/01 00:00 [entrez] AID - S0003-4975(10)64692-9 [pii] AID - 10.1016/s0003-4975(10)64692-9 [doi] PST - ppublish SO - Ann Thorac Surg. 1988 Nov;46(5):536-41. doi: 10.1016/s0003-4975(10)64692-9.