PMID- 31923521 OWN - NLM STAT- MEDLINE DCOM- 20210402 LR - 20210402 IS - 1872-7972 (Electronic) IS - 0304-3940 (Linking) VI - 718 DP - 2020 Jan 23 TI - Mechanism differences between typical yin and typical yang personality individuals assessed by Five-Pattern Personality Inventory (FPPI): Evidence from resting-state brain functional networks. PG - 134745 LID - S0304-3940(20)30015-X [pii] LID - 10.1016/j.neulet.2020.134745 [doi] AB - BACKGROUND: Most studies assessing brain-personality mechanisms have used Western personality questionnaires. However, Western personality questionnaires may not objectively reflect the personality characteristics of individuals in Eastern cultures such as China. Hence, we adopted the functional magnetic resonance imaging (fMRI) and the Chinese localized scale, FPPI, to explore the brain mechanisms differences of typical yin and typical yang personalities of individuals in China. METHODS: 30 typical yin personality participants (TYI) and 34 typical yang personality participants (TYA) were enrolled according to the FPPI. The group differences of the functional brain networks among 90 specific brain regions were mapped using fMRI data and then analyzed by the conventional network metrics (CNM) and frequency subgraph mining (FSM). RESULTS: The CNM and FSM differences between two typical personality groups were traced to the frontal, temporal, and parietal cortices. The yin group, reflecting the rich emotions and feelings of individuals, showed higher betweenness centrality (BCi) and nodal efficiency (Ei) values in putamen and middle frontal gyrus. The yang group, reflecting active behaviors and tendency to adapting to the changing surroundings, showed higher BCi and Ei values in precuneus, posterior cingulate gyrus, and inferior parietal lobule, brain areas in the default mode network (DMN). CONCLUSION: These results supplied evidence for the neurobiological differences between typical yin and typical yang personality participants based on Chinese culture. These results also provide a new perspective to help researchers understand brain mechanism differences between yin and yang personality groups in the Chinese culture. CI - Copyright (c) 2020 The Authors. Published by Elsevier B.V. All rights reserved. FAU - Li, Xiaozhen AU - Li X AD - Department of Psychiatry, First Hospital/First Clinical Medical College of Shanxi Medical University, Taiyuan, China. FAU - Zhuo, Chuanjun AU - Zhuo C AD - Department of Psychiatry and Morbidity, Tianjin Anding Hospital, Tianjin Medical University, Tianjin, China; Department of Psychiatry, Tianjin Medical University, Tianjin, China. FAU - Guo, Hao AU - Guo H AD - College of Information and Computer, Taiyuan University of Technology, Taiyuan, China. FAU - Du, Jian AU - Du J AD - Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China. FAU - Wang, Hao AU - Wang H AD - Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China. FAU - Wang, Junjie AU - Wang J AD - Department of Psychiatry, First Hospital/First Clinical Medical College of Shanxi Medical University, Taiyuan, China. FAU - Li, Jing AU - Li J AD - Department of Psychiatry, First Hospital/First Clinical Medical College of Shanxi Medical University, Taiyuan, China. FAU - Zhao, Wentao AU - Zhao W AD - Department of Psychiatry, First Hospital/First Clinical Medical College of Shanxi Medical University, Taiyuan, China. FAU - Li, Yao AU - Li Y AD - College of Information and Computer, Taiyuan University of Technology, Taiyuan, China. FAU - Sun, Chao AU - Sun C AD - College of Information and Computer, Taiyuan University of Technology, Taiyuan, China. FAU - Zhang, Jingfang AU - Zhang J AD - Department of Humanities and Social Science, Shanxi Medical University, Taiyuan, China. FAU - Yang, Qiuli AU - Yang Q AD - Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China. Electronic address: yql126@126.com. FAU - Xu, Yong AU - Xu Y AD - Department of Psychiatry, First Hospital/First Clinical Medical College of Shanxi Medical University, Taiyuan, China; Department of Humanities and Social Science, Shanxi Medical University, Taiyuan, China. Electronic address: xuyongsmu@vip.163.com. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20200107 PL - Ireland TA - Neurosci Lett JT - Neuroscience letters JID - 7600130 SB - IM MH - Adult MH - Brain/*physiology MH - Brain Mapping MH - China MH - Emotions/physiology MH - Female MH - Frontal Lobe/physiology MH - Gyrus Cinguli/physiology MH - Humans MH - Magnetic Resonance Imaging MH - Male MH - Neural Pathways MH - Parietal Lobe/physiology MH - Personality/*physiology MH - Personality Inventory OTO - NOTNLM OT - Conventional network metrics (CNM) OT - Five-Pattern Personality Inventory (FPPI) OT - Frequency subgraph mining (FSM) OT - Resting-state fMRI OT - Typical personality individuals EDAT- 2020/01/11 06:00 MHDA- 2021/04/07 06:00 CRDT- 2020/01/11 06:00 PHST- 2019/09/26 00:00 [received] PHST- 2019/12/27 00:00 [revised] PHST- 2020/01/06 00:00 [accepted] PHST- 2020/01/11 06:00 [pubmed] PHST- 2021/04/07 06:00 [medline] PHST- 2020/01/11 06:00 [entrez] AID - S0304-3940(20)30015-X [pii] AID - 10.1016/j.neulet.2020.134745 [doi] PST - ppublish SO - Neurosci Lett. 2020 Jan 23;718:134745. doi: 10.1016/j.neulet.2020.134745. Epub 2020 Jan 7.