PMID- 31926223
OWN - NLM
STAT- MEDLINE
DCOM- 20201119
LR  - 20201119
IS  - 1527-5418 (Electronic)
IS  - 0890-8567 (Linking)
VI  - 59
IP  - 3
DP  - 2020 Mar
TI  - Editorial: Mapping the Miswired Connectome in Autism Spectrum Disorder.
PG  - 348-349
LID - S0890-8567(20)30002-2 [pii]
LID - 10.1016/j.jaac.2020.01.001 [doi]
AB  - Unraveling the altered brain-behavior relationships in autism spectrum disorder 
      (ASD) has been challenging because of the limitations of sample size and 
      methodologies that are still evolving. Recently, pediatric neuroimaging has 
      undergone considerable advancement by harnessing resting-state functional 
      magnetic resonance imaging (rfMRI),(1) in which methodologies can be applied to 
      quantify functional connectivity (FC) from spontaneous fluctuations of brain 
      activity. Benefiting from relatively easy data collection from clinical samples 
      and the ability to harmonize these samples, rfMRI has supported the emergence of 
      open pediatric neuroimaging science (OPENS) through the pooling and sharing of 
      large-scale neuroimaging data by and for the research community (eg, the Autism 
      Brain Imaging Data Exchange [ABIDE](2)(,)(3)). Big data OPENS ASD studies have 
      revealed functional impairments in both sensory and cognitive brain networks. 
      However, whether these impairments reflect a miswired connectome of network 
      interplay in ASD remains to be elucidated.
CI  - Copyright (c) 2019 American Academy of Child and Adolescent Psychiatry. Published 
      by Elsevier Inc. All rights reserved.
FAU - Zuo, Xi-Nian
AU  - Zuo XN
AD  - Nanning Normal University, Nanning, Guangxi, China; IDG/McGovern Institute for 
      Brain Research, Beijing Normal University, Beijing, China; University of Chinese 
      Academy of Sciences, Beijing, China. Electronic address: zuoxn@nnnu.edu.cn.
LA  - eng
PT  - Comment
PT  - Editorial
PT  - Research Support, Non-U.S. Gov't
DEP - 20200109
PL  - United States
TA  - J Am Acad Child Adolesc Psychiatry
JT  - Journal of the American Academy of Child and Adolescent Psychiatry
JID - 8704565
SB  - IM
CON - J Am Acad Child Adolesc Psychiatry. 2020 Mar;59(3):422-433. PMID: 31260788
MH  - *Autism Spectrum Disorder/diagnostic imaging
MH  - Brain/diagnostic imaging
MH  - Brain Mapping
MH  - Child
MH  - Cognition
MH  - *Connectome
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Neural Pathways/diagnostic imaging
MH  - Systems Integration
EDAT- 2020/01/12 06:00
MHDA- 2020/11/20 06:00
CRDT- 2020/01/12 06:00
PHST- 2019/09/15 00:00 [received]
PHST- 2019/10/01 00:00 [revised]
PHST- 2020/01/02 00:00 [accepted]
PHST- 2020/01/12 06:00 [pubmed]
PHST- 2020/11/20 06:00 [medline]
PHST- 2020/01/12 06:00 [entrez]
AID - S0890-8567(20)30002-2 [pii]
AID - 10.1016/j.jaac.2020.01.001 [doi]
PST - ppublish
SO  - J Am Acad Child Adolesc Psychiatry. 2020 Mar;59(3):348-349. doi: 
      10.1016/j.jaac.2020.01.001. Epub 2020 Jan 9.