PMID- 31937726
OWN - NLM
STAT- MEDLINE
DCOM- 20201215
LR  - 20240328
IS  - 1998-3689 (Electronic)
IS  - 0301-4738 (Print)
IS  - 0301-4738 (Linking)
VI  - 68
IP  - Suppl 1
DP  - 2020 Feb
TI  - Spectrum of Eye Disease in Diabetes (SPEED) in India: A prospective 
      facility-based study. Report # 4. Glaucoma in people with type 2 diabetes 
      mellitus.
PG  - S32-S36
LID - 10.4103/ijo.IJO_1948_19 [doi]
AB  - PURPOSE: To estimate the proportion of people with type 2 diabetes mellitus 
      (T2DM) and glaucoma in a facility-based cross-sectional observational study in 
      India. METHODS: All people received a comprehensive eye examination. 
      Glaucoma-specific examinations included applanation tonometry, optic disc and cup 
      evaluation, and stereo biomicroscopy in all people; gonioscopy and visual field 
      testing in glaucoma suspects. The International Society of Geographic and 
      Epidemiologic Ophthalmology guidelines were used to diagnose and classify 
      glaucoma. RESULTS: The study recruited 11,182 people (average age: 58.2 +/- 10.6; 
      range 39-96 years). Glaucoma was diagnosed in 4.9% (n = 547) people. About 76.8% 
      (n = 420) of those with glaucoma had bilateral disease, and 98.7% (n = 540) were 
      >40 years. Among people with bilateral disease, 94.5% (n = 397) had primary 
      glaucoma - open angle in 59.3% (n = 228) and angle closure in 40.2% (n = 169). 
      Diabetes duration was </=10 years in 71.5% (n = 300) people. On linear regression, 
      the following were associated with glaucoma: advancing age [compared with < 40 
      years age group; odds ratio [OR] in 50-60 year age group: 1.36 [95% confidence 
      interval (CI): 1.01-1.8], P < 0.035); >60 years age group (OR: 2.05, 95% CI: 
      1.57-2.67; P < 0.001), and diabetic neuropathy (OR: 2.62, 95% CI: 1.35-5.10, P < 
      0.003). Glycemic control did not have significant association (P = 0.425). 
      CONCLUSION: Presence of glaucoma in people with T2DM in this cohort was similar 
      to the general population prevalence studies in India. Glaucoma was invariably 
      bilateral. A comprehensive eye examination in people age 40 years and older with 
      diabetes and/or glaucoma is beneficial.
FAU - Behera, Umesh C
AU  - Behera UC
AD  - Retina Vitreous Service, L V Prasad Eye Institute, Bhubaneswar, Odisha, India.
FAU - Bhattacharjee, Harsha
AU  - Bhattacharjee H
AD  - Retina Vitreous Service, Sri Sankaradeva Nethralaya, Guwahati, Assam, India.
FAU - Das, Taraprasad
AU  - Das T
AD  - Retina Vitreous Service, L V Prasad Eye Institute, Hyderabad, Telangana, India.
FAU - Gilbert, Clare
AU  - Gilbert C
AD  - Department of Clinical Research, London School of Hygiene and Tropical Medicine, 
      London, UK.
FAU - Murthy, G V S
AU  - Murthy GVS
AD  - Department of Clinical Research, Indian School of Public Health, Public Health 
      Foundation of India, Hyderabad, Telangana, India.
FAU - Rajalakshmi, R
AU  - Rajalakshmi R
AD  - Department of Ophthalmology, Dr Mohan's Diabetes Foundation, Chennai, Tamil Nadu, 
      India.
FAU - Pant, Hira B
AU  - Pant HB
AD  - Department of Clinical Research, Indian School of Public Health, Public Health 
      Foundation of India, Hyderabad, Telangana, India.
CN  - SPEED study group
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
PL  - India
TA  - Indian J Ophthalmol
JT  - Indian journal of ophthalmology
JID - 0405376
SB  - IM
MH  - Adult
MH  - Age Distribution
MH  - Aged
MH  - Aged, 80 and over
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/*complications/epidemiology
MH  - Diabetic Retinopathy/*epidemiology/etiology
MH  - Female
MH  - Follow-Up Studies
MH  - Glaucoma/*epidemiology/etiology
MH  - Hospitals/*statistics & numerical data
MH  - Humans
MH  - Incidence
MH  - India/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Risk Assessment/*methods
MH  - *Rural Population
MH  - Sex Distribution
MH  - *Urban Population
MH  - Young Adult
PMC - PMC7001170
OTO - NOTNLM
OT  - Diabetes
OT  - diabetic retinopathy
OT  - glaucoma
COIS- None
EDAT- 2020/01/16 06:00
MHDA- 2020/12/16 06:00
PMCR- 2020/02/01
CRDT- 2020/01/16 06:00
PHST- 2020/01/16 06:00 [entrez]
PHST- 2020/01/16 06:00 [pubmed]
PHST- 2020/12/16 06:00 [medline]
PHST- 2020/02/01 00:00 [pmc-release]
AID - IndianJOphthalmol_2020_68_13_32_275732 [pii]
AID - IJO-68-32 [pii]
AID - 10.4103/ijo.IJO_1948_19 [doi]
PST - ppublish
SO  - Indian J Ophthalmol. 2020 Feb;68(Suppl 1):S32-S36. doi: 10.4103/ijo.IJO_1948_19.