PMID- 31942435
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2211-5072 (Electronic)
IS  - 2211-5056 (Print)
IS  - 2211-5056 (Linking)
VI  - 9
IP  - 4
DP  - 2019 Oct-Dec
TI  - Spectral-domain optical coherence tomography finding of acute retinal pigment 
      epitheliitis.
PG  - 276-279
LID - 10.4103/tjo.tjo_23_19 [doi]
AB  - Acute retinal pigment epitheliitis (ARPE) is a rare, transient macular disorder 
      affecting healthy young adults. We describe the morphologic appearance of the 
      retina by spectral-domain optical coherence tomography (SD-OCT) and to evaluate 
      both the anatomic changes and the functional visual acuity changes over time in 
      the course of disease. A 35-year-old healthy male presented with 1-week history 
      of sudden-onset bilateral central scotoma with blurry vision. He denied trauma, 
      excessive sun exposure, or drug abuse history or alkyl nitrites before. The 
      medical and ocular examinations were unremarkable. The best-corrected visual 
      acuity (BCVA) was 20/200 (OU) at the initial visit. Slit-lamp examination result 
      was normal. Fundus examination revealed subfoveal yellowish lesions with a 
      halo-like pigment in both eyes. The SD-OCT imaging showed subtle disruption of 
      the retinal pigment epithelium (RPE) and abnormal hyperreflectivity throughout 
      the full thickness of the foveola in both eyes. Six weeks later, the BCVA 
      improved to 20/30 (OU) without any treatment. Six months later, the BCVA observed 
      deteriorated to 20/50 (OU). SD-OCT demonstrated ellipsoid zone and cone outer 
      segment tips line defects at the fovea with sharply defined borders. One year 
      later from the initial visit, the BCVA improved to 20/20 (OU), but persisted 
      macular microhole presents on the SD-OCT. The patient was followed for 1 year 
      without any treatment. Thereafter, we noted that in the case of poor initial 
      visual acuity, external limiting membrane, or outer nuclear layer involvement, as 
      determined by SD-OCT, at the baseline might need longer time for visual acuity. 
      The natural course of ARPE may involve the demonstration of a minor outer retinal 
      defect that is similar to a macular microhole. In ARPE, like SD-OCT findings, the 
      location of the initial lesion is the photoreceptor outer segments. It is not 
      just limited to the RPE.
CI  - Copyright: (c) 2019 Taiwan J Ophthalmol.
FAU - Li, Yi-Hsuan
AU  - Li YH
AD  - Department of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung, 
      Taiwan.
FAU - Chang, Yo-Chen
AU  - Chang YC
AD  - Department of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung, 
      Taiwan.
AD  - Department of Ophthalmology, School of Medicine, Kaohsiung Medical University, 
      Kaohsiung, Taiwan.
FAU - Wu, Wen-Chuan
AU  - Wu WC
AD  - Department of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung, 
      Taiwan.
AD  - Department of Ophthalmology, School of Medicine, Kaohsiung Medical University, 
      Kaohsiung, Taiwan.
LA  - eng
PT  - Case Reports
DEP - 20191213
PL  - India
TA  - Taiwan J Ophthalmol
JT  - Taiwan journal of ophthalmology
JID - 101582127
PMC - PMC6947752
OTO - NOTNLM
OT  - Acute retinal pigment epitheliitis
OT  - inflammation
OT  - optical coherence tomography
OT  - photoreceptors
OT  - retinal pigment epithelium
COIS- The authors declare that there are no conflicts of interests of this paper.
EDAT- 2020/01/17 06:00
MHDA- 2020/01/17 06:01
PMCR- 2019/12/13
CRDT- 2020/01/17 06:00
PHST- 2019/03/10 00:00 [received]
PHST- 2019/07/14 00:00 [accepted]
PHST- 2020/01/17 06:00 [entrez]
PHST- 2020/01/17 06:00 [pubmed]
PHST- 2020/01/17 06:01 [medline]
PHST- 2019/12/13 00:00 [pmc-release]
AID - TJO-9-276 [pii]
AID - 10.4103/tjo.tjo_23_19 [doi]
PST - epublish
SO  - Taiwan J Ophthalmol. 2019 Dec 13;9(4):276-279. doi: 10.4103/tjo.tjo_23_19. 
      eCollection 2019 Oct-Dec.