PMID- 31943823
OWN - NLM
STAT- MEDLINE
DCOM- 20210719
LR  - 20210719
IS  - 2040-7947 (Electronic)
IS  - 2040-7939 (Linking)
VI  - 36
IP  - 4
DP  - 2020 Apr
TI  - Towards efficient design optimization of a miniaturized thermoelectric generator 
      for electrically active implants via model order reduction and submodeling 
      technique.
PG  - e3311
LID - 10.1002/cnm.3311 [doi]
AB  - Thermoelectric generators (TEG) convert the thermal energy into electrical energy 
      and are under investigation as a power supply for medical implants. To improve 
      the performance of TEG, the design optimization process through finite element 
      model simulation is preferred by biomedical engineers. This paper aims to provide 
      an efficient method of speeding up the design optimization process of TEG. A 
      three-dimensional realistic human torso model incorporating the TEG is 
      investigated, where the internal heat transfer in human tissue is characterized 
      by Pennes bioheat equation. In addition, convection, radiation, and evaporation 
      effects at the skin surface are applied to identify the heat transfer effects 
      between the human body and the environment. To speed up finite element simulation 
      of the large-scale human torso model, projection-based model order reduction 
      (MOR) is applied for generation of a compact but highly accurate model. 
      Parametric MOR (pMOR) further enables generating a parameter-independent compact 
      model. For an efficient design optimization of TEG, this compact human torso 
      model is applied within a thermal submodeling approach. Its temperature 
      distribution results are back-projected and used as boundary conditions for the 
      TEG submodel. The achieved speed-up in simulation time, demonstrated in this 
      work, clearly indicates that the design optimization process of TEG is more 
      efficient with the combination of MOR and submodeling techniques.
CI  - (c) 2020 The Authors. International Journal for Numerical Methods in Biomedical 
      Engineering published by John Wiley & Sons Ltd.
FAU - Yuan, Chengdong
AU  - Yuan C
AUID- ORCID: 0000-0002-2204-6814
AD  - Department of Engineering, Jade University of Applied Sciences, Wilhelmshaven, 
      Germany.
AD  - Institute of Electronic Appliances and Circuits, University of Rostock, Rostock, 
      Germany.
FAU - Kress, Stefanie
AU  - Kress S
AD  - Institute of Electronic Appliances and Circuits, University of Rostock, Rostock, 
      Germany.
FAU - Sadashivaiah, Gunasheela
AU  - Sadashivaiah G
AD  - Institute of Electronic Appliances and Circuits, University of Rostock, Rostock, 
      Germany.
FAU - Rudnyi, Evgenii B
AU  - Rudnyi EB
AD  - CADFEM GmbH, Grafing b. Munchen, Germany.
FAU - Hohlfeld, Dennis
AU  - Hohlfeld D
AD  - Institute of Electronic Appliances and Circuits, University of Rostock, Rostock, 
      Germany.
FAU - Bechtold, Tamara
AU  - Bechtold T
AD  - Department of Engineering, Jade University of Applied Sciences, Wilhelmshaven, 
      Germany.
AD  - Institute of Electronic Appliances and Circuits, University of Rostock, Rostock, 
      Germany.
LA  - eng
PT  - Journal Article
DEP - 20200221
PL  - England
TA  - Int J Numer Method Biomed Eng
JT  - International journal for numerical methods in biomedical engineering
JID - 101530293
SB  - IM
MH  - *Computer Simulation
MH  - Finite Element Analysis
MH  - Humans
MH  - Temperature
OTO - NOTNLM
OT  - bioheat modeling
OT  - energy harvesting
OT  - finite element method
OT  - implantable biomedical devices
OT  - model order reduction
OT  - thermoelectric generator
EDAT- 2020/01/17 06:00
MHDA- 2021/07/20 06:00
CRDT- 2020/01/17 06:00
PHST- 2019/07/05 00:00 [received]
PHST- 2019/11/09 00:00 [revised]
PHST- 2020/01/10 00:00 [accepted]
PHST- 2020/01/17 06:00 [pubmed]
PHST- 2021/07/20 06:00 [medline]
PHST- 2020/01/17 06:00 [entrez]
AID - 10.1002/cnm.3311 [doi]
PST - ppublish
SO  - Int J Numer Method Biomed Eng. 2020 Apr;36(4):e3311. doi: 10.1002/cnm.3311. Epub 
      2020 Feb 21.