PMID- 31949765 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200325 IS - 1936-2625 (Electronic) IS - 1936-2625 (Linking) VI - 11 IP - 7 DP - 2018 TI - Primary pulmonary synovial sarcoma: a case report. PG - 3789-3792 AB - Primary pulmonary synovial sarcoma (PPSS) is a relatively rare mesenchymal tumor accounting for 0.5% of all primary lung malignancy with a highly progressive potential. We describe a case of a 52-year-old man whose chest CT-imaging revealed a heterogeneous mass (8.5 x 7.7 x 6.5 cm), with multiple nearly-circular nodules in bilateral pulmonary tissues. EBUS-TBNA and pathological H&E and immunohistochemical examination were performed subsequently, and sarcoma was suspected. Then molecular detection was used and PPSS was confirmed by the detection of the expression of SYT gene (positive) and EWSR1 gene (negative) in situ hybridization. This report shows that EBUS-TBNA combined with in situ hybridization could serve as a helpful diagnostic tool. CI - IJCEP Copyright (c) 2018. FAU - Liu, Junfeng AU - Liu J AD - Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University Guangzhou, People's Republic of China. FAU - Nie, Zhaoming AU - Nie Z AD - Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University Guangzhou, People's Republic of China. FAU - Lv, Jianyao AU - Lv J AD - Department of Medical Imaging, The First Affiliated Hospital of Sun Yat-sen University Guangzhou, People's Republic of China. FAU - Lai, Yingrong AU - Lai Y AD - Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University Guangzhou, People's Republic of China. LA - eng PT - Case Reports DEP - 20180701 PL - United States TA - Int J Clin Exp Pathol JT - International journal of clinical and experimental pathology JID - 101480565 PMC - PMC6962852 OTO - NOTNLM OT - EWSR1 gene OT - Primary pulmonary synovial sarcoma OT - SYT gene OT - diagnosis COIS- None. EDAT- 2018/07/01 00:00 MHDA- 2018/07/01 00:01 PMCR- 2018/07/01 CRDT- 2020/01/18 06:00 PHST- 2018/03/28 00:00 [received] PHST- 2018/04/28 00:00 [accepted] PHST- 2020/01/18 06:00 [entrez] PHST- 2018/07/01 00:00 [pubmed] PHST- 2018/07/01 00:01 [medline] PHST- 2018/07/01 00:00 [pmc-release] PST - epublish SO - Int J Clin Exp Pathol. 2018 Jul 1;11(7):3789-3792. eCollection 2018.