PMID- 31952945
OWN - NLM
STAT- MEDLINE
DCOM- 20210309
LR  - 20210309
IS  - 1532-8406 (Electronic)
IS  - 0883-5403 (Print)
IS  - 0883-5403 (Linking)
VI  - 35
IP  - 5
DP  - 2020 May
TI  - Validation of the Hip Disability and Osteoarthritis Outcome Score and Knee Injury 
      and Osteoarthritis Outcome Score Pain and Function Subscales for Use in Total Hip 
      Replacement and Total Knee Replacement Clinical Trials.
PG  - 1200-1207.e4
LID - S0883-5403(19)31187-8 [pii]
LID - 10.1016/j.arth.2019.12.038 [doi]
AB  - BACKGROUND: Total hip replacement (THR)/total knee replacement (TKR) studies do 
      not uniformly measure patient centered domains, pain, and function. We aim to 
      validate existing measures of pain and function within subscales of standard 
      instruments to facilitate measurement. METHODS: We evaluated baseline and 2-year 
      pain and function for THR and TKR using Hip disability and Osteoarthritis Outcome 
      Score (HOOS)/Knee Injury and Osteoarthritis Outcome Score (KOOS), with primary 
      unilateral TKR (4796) and THR (4801). Construct validity was assessed by 
      correlating HOOS/KOOS pain and activities of daily living (ADL), function quality 
      of life (QOL), and satisfaction using Spearman correlation coefficients. Patient 
      relevant thresholds for change in pain and function were anchored to improvement 
      in QOL; minimally clinically important difference (MCID) corresponded to "a 
      little improvement" and a really important difference (RID) to a "moderate 
      improvement." Pain and ADL function scores were compared by quartiles using 
      Kruskal-Wallis. RESULTS: Two-year HOOS/KOOS pain and ADL function correlated with 
      health-related QOL (KOOS pain and Short Form 12 Physical Component Scale rho = 
      0.54; function rho = 0.63). Comparing QOL by pain and function quartiles, the 
      highest levels of pain relief and function were associated with the most improved 
      QOL. MCID for pain was estimated at >/=20, and the RID >/=29; MCID for function >/=14, 
      and the RID >/=23. The measures were responsive to change with large effect sizes 
      (>/=1.8). CONCLUSION: We confirm that HOOS/KOOS pain and ADL function subscales are 
      valid measures of critical patient centered domains after THR/TKR, and achievable 
      thresholds anchored to improved QOL. Cost-free availability and brevity makes 
      them feasible, to be used in a core measurement set in total joint replacement 
      trials.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Goodman, Susan M
AU  - Goodman SM
AD  - Department of Medicine, Hospital for Special Surgery, New York, NY.
FAU - Mehta, Bella Y
AU  - Mehta BY
AD  - Department of Medicine, Hospital for Special Surgery, New York, NY.
FAU - Mandl, Lisa A
AU  - Mandl LA
AD  - Department of Medicine, Hospital for Special Surgery, New York, NY.
FAU - Szymonifka, Jackie D
AU  - Szymonifka JD
AD  - Department of Medicine, Hospital for Special Surgery, New York, NY; Division of 
      Biostatistics, Department of Public Health, New York University, New York, NY.
FAU - Finik, Jackie
AU  - Finik J
AD  - City University of New York Graduate School of Public Health, New York, NY.
FAU - Figgie, Mark P
AU  - Figgie MP
AD  - Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY.
FAU - Navarro-Millan, Iris Y
AU  - Navarro-Millan IY
AD  - Department of Medicine, Hospital for Special Surgery, New York, NY; Department of 
      Medicine, Weill Medical College of Cornell University, New York, NY.
FAU - Bostrom, Mathias P
AU  - Bostrom MP
AD  - Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY.
FAU - Parks, Michael L
AU  - Parks ML
AD  - Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY.
FAU - Padgett, Douglas E
AU  - Padgett DE
AD  - Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY.
FAU - McLawhorn, Alexander S
AU  - McLawhorn AS
AD  - Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY.
FAU - Antao, Vinicius C
AU  - Antao VC
AD  - Center for the Advancement of Value in Musculoskeletal Care, Hospital for Special 
      Surgery, New York, NY.
FAU - Yates, Adolph J
AU  - Yates AJ
AD  - Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA.
FAU - Springer, Bryan D
AU  - Springer BD
AD  - Department of Orthopaedic Surgery, OrthoCarolina Hip and Knee Center, Charlotte, 
      NC.
FAU - Lyman, Stephen L
AU  - Lyman SL
AD  - Healthcare Research Institute, Hospital for Special Surgery, New York, NY.
FAU - Singh, Jasvinder A
AU  - Singh JA
AD  - Division of Epidemiology at the School of Public Health, Department of Medicine 
      at the School of Medicine, The University of Alabama at Birmingham Medical 
      Center, Birmingham, AL.
LA  - eng
GR  - K23 AR068449/AR/NIAMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20191227
PL  - United States
TA  - J Arthroplasty
JT  - The Journal of arthroplasty
JID - 8703515
SB  - IM
MH  - Activities of Daily Living
MH  - *Arthroplasty, Replacement, Hip/adverse effects
MH  - *Arthroplasty, Replacement, Knee/adverse effects
MH  - Humans
MH  - *Knee Injuries
MH  - *Osteoarthritis, Hip/surgery
MH  - *Osteoarthritis, Knee/surgery
MH  - Pain
MH  - Quality of Life
MH  - Treatment Outcome
PMC - PMC7193650
MID - NIHMS1578545
OTO - NOTNLM
OT  - HOOS
OT  - KOOS
OT  - subscale
OT  - total hip arthroplasty
OT  - total knee arthroplasty
OT  - validation
EDAT- 2020/01/19 06:00
MHDA- 2021/03/10 06:00
PMCR- 2020/11/01
CRDT- 2020/01/19 06:00
PHST- 2019/09/18 00:00 [received]
PHST- 2019/12/10 00:00 [revised]
PHST- 2019/12/18 00:00 [accepted]
PHST- 2020/01/19 06:00 [pubmed]
PHST- 2021/03/10 06:00 [medline]
PHST- 2020/01/19 06:00 [entrez]
PHST- 2020/11/01 00:00 [pmc-release]
AID - S0883-5403(19)31187-8 [pii]
AID - 10.1016/j.arth.2019.12.038 [doi]
PST - ppublish
SO  - J Arthroplasty. 2020 May;35(5):1200-1207.e4. doi: 10.1016/j.arth.2019.12.038. 
      Epub 2019 Dec 27.