PMID- 31953077
OWN - NLM
STAT- MEDLINE
DCOM- 20200928
LR  - 20200928
IS  - 1532-821X (Electronic)
IS  - 0003-9993 (Linking)
VI  - 101
IP  - 6
DP  - 2020 Jun
TI  - A Standard Method for Determining the Minimal Clinically Important Difference for 
      Rehabilitation Measures.
PG  - 1090-1094
LID - S0003-9993(20)30003-4 [pii]
LID - 10.1016/j.apmr.2019.12.008 [doi]
AB  - The minimal clinically important difference (MCID) is receiving increasing 
      interest and importance in medical practice and research. The MCID is the 
      smallest improvement in scores in the domain of interest that patients perceive 
      as beneficial. In clinical trials, comparing the proportion of individuals 
      between treatment and control groups who obtain a MCID may be more informative 
      than comparisons of mean change between groups because a statistically 
      significant mean difference does not necessarily represent a difference that is 
      perceived as meaningful by treatment recipients. The MCID may also be useful in 
      advancing personalized medicine by characterizing those who are most likely to 
      benefit from a treatment. In clinical practice, the MCID can be used to identify 
      if a participant is experiencing a meaningful change in status. A variety of 
      methods have been used to determine the MCID with no clear agreement on the most 
      appropriate approach. Two major sets of methods are either (1) 
      distribution-based, that is, referencing the MCID to a measure of variability or 
      effect size in the measure of interest or (2) anchor-based, that is, referencing 
      the MCID to an external assessment of change in the condition, ability, or 
      activity represented by the measure of interest. In prior literature, using 
      multiple methods to "triangulate" on the value of the MCID has been proposed. In 
      this commentary, we describe a systematic approach to triangulate on the MCID 
      using both distribution-based and anchor-based methods. Adaptation of a 
      systematic approach for obtaining the MCID in rehabilitation would facilitate 
      communication and comparison of results among rehabilitation researchers and 
      providers.
CI  - Copyright (c) 2020 American Congress of Rehabilitation Medicine. Published by 
      Elsevier Inc. All rights reserved.
FAU - Malec, James F
AU  - Malec JF
AD  - Department of Physical Medicine and Rehabilitation, Indiana University School of 
      Medicine, Indianapolis, Indiana; Department of Psychology, Mayo Clinic, 
      Rochester, Minnesota. Electronic address: jfmalec@iupui.edu.
FAU - Ketchum, Jessica M
AU  - Ketchum JM
AD  - Research Department, Craig Hospital, Englewood, Colorado; Traumatic Brain Injury 
      Model Systems National Data and Statistical Center, Englewood, Colorado.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200115
PL  - United States
TA  - Arch Phys Med Rehabil
JT  - Archives of physical medicine and rehabilitation
JID - 2985158R
SB  - IM
MH  - Humans
MH  - *Minimal Clinically Important Difference
MH  - Physical and Rehabilitation Medicine/*standards
OTO - NOTNLM
OT  - Minimal clinically important difference
OT  - Outcome and process assessment, health care
OT  - Patient outcome assessment
OT  - Quality of health care
OT  - Rehabilitation
EDAT- 2020/01/19 06:00
MHDA- 2020/09/29 06:00
CRDT- 2020/01/19 06:00
PHST- 2019/08/31 00:00 [received]
PHST- 2019/12/16 00:00 [revised]
PHST- 2019/12/18 00:00 [accepted]
PHST- 2020/01/19 06:00 [pubmed]
PHST- 2020/09/29 06:00 [medline]
PHST- 2020/01/19 06:00 [entrez]
AID - S0003-9993(20)30003-4 [pii]
AID - 10.1016/j.apmr.2019.12.008 [doi]
PST - ppublish
SO  - Arch Phys Med Rehabil. 2020 Jun;101(6):1090-1094. doi: 
      10.1016/j.apmr.2019.12.008. Epub 2020 Jan 15.