PMID- 31956731
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240327
IS  - 2452-199X (Electronic)
IS  - 2452-199X (Linking)
VI  - 5
IP  - 1
DP  - 2020 Mar
TI  - A comparative study of the osteogenic performance between the hierarchical 
      micro/submicro-textured 3D-printed Ti6Al4V surface and the SLA surface.
PG  - 9-16
LID - 10.1016/j.bioactmat.2019.12.008 [doi]
AB  - Three-dimensional (3D) printed titanium and its alloys have broad application 
      prospect in the field of biomedical implant materials, although the biological 
      performance of the original surface should be improved. Learning from the 
      development experience of conventional titanium implants, to construct a 
      hierarchical hybrid topological surface is the future direction of efforts. Since 
      the original 3D-printed (3D hereafter) Ti6Al4V surface inherently has 
      micron-scale features, in the present study, we introduced submicron-scale pits 
      on the original surface by acid etching to obtain a hierarchical 
      micro/submicro-textured surface. The characteristic and biological performance of 
      the 3D-printed and acid-etched (3DA hereafter) surface were evaluated in vitro 
      and in vivo, compared with the conventional sandblasted, large-grit, acid-etched 
      (SLA hereafter) surface. Our results suggested the adhesion, proliferation and 
      osteogenic differentiation of bone marrow derived mesenchymal stromal cells 
      (BMSCs), as well as the in vivo osseointegration on 3DA surfaces were 
      significantly improved. However, the overall osteogenic performance of the 3DA 
      surface was not as good as the conventional SLA surface.
CI  - (c) 2020 Production and hosting by Elsevier B.V. on behalf of KeAi Communications 
      Co., Ltd.
FAU - Zhang, Jinkai
AU  - Zhang J
AD  - Department of Orthodontics, School & Hospital of Stomatology, Tongji University; 
      Shanghai Engineering Research Center of Tooth Restoration and Regeneration, 
      Shanghai, 200072, China.
FAU - Liu, Jiaqiang
AU  - Liu J
AD  - Department of Oral & Cranio-Maxillofacial Surgery, Shanghai Ninth People's 
      Hospital, College of Stomatology, Shanghai Jiao Tong University School of 
      Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key 
      Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, 
      200011, China.
FAU - Wang, Chengtao
AU  - Wang C
AD  - School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, 
      200240, China.
FAU - Chen, Fengshan
AU  - Chen F
AD  - Department of Orthodontics, School & Hospital of Stomatology, Tongji University; 
      Shanghai Engineering Research Center of Tooth Restoration and Regeneration, 
      Shanghai, 200072, China.
FAU - Wang, Xudong
AU  - Wang X
AD  - Department of Oral & Cranio-Maxillofacial Surgery, Shanghai Ninth People's 
      Hospital, College of Stomatology, Shanghai Jiao Tong University School of 
      Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key 
      Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, 
      200011, China.
FAU - Lin, Kaili
AU  - Lin K
AD  - Department of Oral & Cranio-Maxillofacial Surgery, Shanghai Ninth People's 
      Hospital, College of Stomatology, Shanghai Jiao Tong University School of 
      Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key 
      Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, 
      200011, China.
LA  - eng
PT  - Journal Article
DEP - 20200109
PL  - China
TA  - Bioact Mater
JT  - Bioactive materials
JID - 101685294
PMC - PMC6956677
OTO - NOTNLM
OT  - 3D printing
OT  - Osteogenesis
OT  - SLA
OT  - Surface modification
OT  - Ti6Al4V
COIS- The authors have no potential conflict of interests to disclose.
EDAT- 2020/01/21 06:00
MHDA- 2020/01/21 06:01
PMCR- 2020/01/09
CRDT- 2020/01/21 06:00
PHST- 2019/12/02 00:00 [received]
PHST- 2019/12/28 00:00 [revised]
PHST- 2019/12/28 00:00 [accepted]
PHST- 2020/01/21 06:00 [entrez]
PHST- 2020/01/21 06:00 [pubmed]
PHST- 2020/01/21 06:01 [medline]
PHST- 2020/01/09 00:00 [pmc-release]
AID - S2452-199X(19)30076-3 [pii]
AID - 10.1016/j.bioactmat.2019.12.008 [doi]
PST - epublish
SO  - Bioact Mater. 2020 Jan 9;5(1):9-16. doi: 10.1016/j.bioactmat.2019.12.008. 
      eCollection 2020 Mar.