PMID- 31966752
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200126
IS  - 1936-2625 (Electronic)
IS  - 1936-2625 (Linking)
VI  - 10
IP  - 8
DP  - 2017
TI  - Spinal lesion as the first manifestation of high-grade B-cell lymphoma, with MYC 
      and BCL2 rearrangements.
PG  - 8858-8862
AB  - High-grade B-cell lymphoma with MYC and BCL2 rearrangements is a rare lymphoma 
      which has highly aggressive clinical manifestations. The reporting case is a 
      72-year-old female presented with lumbago and weakness in the lower limb due to a 
      mass at T8-10 revealed by computed tomography (CT) scan. Histological feature of 
      the lesion shows an abundant and diffuse large lymphoid cells infiltration. 
      Immunophenotype meets with germ center B cell (GCB) lymphoma (Hans algorithm). 
      C-MYC and BCL2 gene rearrangements are detected by fluorescence in situ 
      hybridization (FISH). It's a rare and typical case of high-grade B-cell lymphoma 
      with MYC and BCL2 rearrangements with uncommon clinical manifestation.
CI  - IJCEP Copyright (c) 2017.
FAU - Ye, Yunxia
AU  - Ye Y
AD  - Department of Pathology, West China Hospital of Sichuan University Chengdu, 
      Sichuan Province, China.
FAU - Zhang, Wenyan
AU  - Zhang W
AD  - Department of Pathology, West China Hospital of Sichuan University Chengdu, 
      Sichuan Province, China.
FAU - Zhao, Sha
AU  - Zhao S
AD  - Department of Pathology, West China Hospital of Sichuan University Chengdu, 
      Sichuan Province, China.
FAU - Jiang, Lili
AU  - Jiang L
AD  - Department of Pathology, West China Hospital of Sichuan University Chengdu, 
      Sichuan Province, China.
FAU - Liu, Weiping
AU  - Liu W
AD  - Department of Pathology, West China Hospital of Sichuan University Chengdu, 
      Sichuan Province, China.
FAU - Long, Yanhong
AU  - Long Y
AD  - Department of Pathology, West China Hospital of Sichuan University Chengdu, 
      Sichuan Province, China.
FAU - Wan, Ying
AU  - Wan Y
AD  - Department of Pathology, West China Hospital of Sichuan University Chengdu, 
      Sichuan Province, China.
LA  - eng
PT  - Case Reports
DEP - 20170801
PL  - United States
TA  - Int J Clin Exp Pathol
JT  - International journal of clinical and experimental pathology
JID - 101480565
PMC - PMC6965433
OTO - NOTNLM
OT  - BCL2
OT  - MYC
OT  - Spinal
OT  - gene rearrangement
OT  - high-grade B-cell lymphoma
COIS- None.
EDAT- 2017/08/01 00:00
MHDA- 2017/08/01 00:01
PMCR- 2017/08/01
CRDT- 2020/01/23 06:00
PHST- 2017/05/14 00:00 [received]
PHST- 2017/06/20 00:00 [accepted]
PHST- 2020/01/23 06:00 [entrez]
PHST- 2017/08/01 00:00 [pubmed]
PHST- 2017/08/01 00:01 [medline]
PHST- 2017/08/01 00:00 [pmc-release]
PST - epublish
SO  - Int J Clin Exp Pathol. 2017 Aug 1;10(8):8858-8862. eCollection 2017.