PMID- 31974734
OWN - NLM
STAT- MEDLINE
DCOM- 20210823
LR  - 20240109
IS  - 2196-8837 (Electronic)
IS  - 2196-8837 (Linking)
VI  - 7
IP  - 4
DP  - 2020 Aug
TI  - A Systematic Review of Environmental Health Outcomes in Selected American Indian 
      and Alaska Native Populations.
PG  - 698-739
LID - 10.1007/s40615-020-00700-2 [doi]
AB  - BACKGROUND: Economic and social marginalization among American Indians and Alaska 
      Natives (AI/ANs) results in higher chronic disease prevalence. Potential causal 
      associations between toxic environmental exposures and adverse health outcomes 
      within AI/AN communities are not well understood. OBJECTIVES: This review 
      examines epidemiological literature on exposure to toxicants and associated 
      adverse health outcomes among AI/AN populations. METHODS: PubMed, Embase, 
      Cochrane, Environment Complete, Web of Science Plus, DART, and ToxLine were 
      searched for English-language articles. The following data were extracted: lead 
      author's last name, publication year, cohort name, study location, AI/AN tribe, 
      study initiation and conclusion, sample size, primary characteristic, 
      environmental exposure, health outcomes, risk estimates, and covariates. RESULTS: 
      About 31 articles on three types of environmental exposures met inclusion 
      criteria: persistent organic pollutants (POPs), heavy metals, and open dumpsites. 
      Of these, 17 addressed exposure to POPs, 10 heavy metal exposure, 2 exposure to 
      both POPs and heavy metals, and 2 exposure to open dumpsites. Studies on the 
      Mohawk Nation at Akwesasne; Yupik on St. Lawrence Island, Alaska; Navajo Nation; 
      Gila River Indian Community; Cheyenne River Sioux; 197 Alaska Native villages; 
      and 13 tribes in Arizona, Oklahoma, North Dakota, and South Dakota that 
      participated in the Strong Heart Study support associations between toxicant 
      exposure and various chronic conditions including cardiovascular conditions, 
      reproductive abnormalities, cancer, autoimmune disorders, neurological deficits, 
      and diabetes. DISCUSSION: The complex interplay of environmental and social 
      factors in disease etiology among AI/ANs is a product of externally imposed 
      environmental exposures, systemic discrimination, and modifiable risk behaviors. 
      The connection between environmental health disparities and adverse health 
      outcomes indicates a need for further study.
FAU - Meltzer, Gabriella Y
AU  - Meltzer GY
AUID- ORCID: 0000-0002-6885-9730
AD  - Department of Social and Behavioral Sciences, New York University School of 
      Global Public Health, 715/719 Broadway, New York, NY, 10003, USA. gm2477@nyu.edu.
FAU - Watkins, Beverly-Xaviera
AU  - Watkins BX
AUID- ORCID: 0000-0002-7677-7575
AD  - Department of Epidemiology, New York University School of Global Public Health, 
      715/719 Broadway, New York, NY, 10003, USA.
FAU - Vieira, Dorice
AU  - Vieira D
AUID- ORCID: 0000-0003-4232-9413
AD  - Health Sciences Library, New York University School of Medicine, 550 First 
      Avenue, New York, NY, 10016, USA.
FAU - Zelikoff, Judith T
AU  - Zelikoff JT
AUID- ORCID: 0000-0002-4547-2218
AD  - Department of Environmental Medicine, New York University School of Medicine, 341 
      East 25th Street, New York, NY, 10010, USA.
FAU - Boden-Albala, Bernadette
AU  - Boden-Albala B
AUID- ORCID: 0000-0002-3752-329X
AD  - Department of Population Health, University of California Irvine, 653 East 
      Peltason Drive, Irvine, CA, 92697, USA.
LA  - eng
PT  - Journal Article
PT  - Systematic Review
DEP - 20200123
PL  - Switzerland
TA  - J Racial Ethn Health Disparities
JT  - Journal of racial and ethnic health disparities
JID - 101628476
RN  - 0 (Hazardous Substances)
SB  - IM
MH  - Alaska Natives/*statistics & numerical data
MH  - Chronic Disease/*epidemiology/*ethnology
MH  - *Environmental Health
MH  - Female
MH  - Hazardous Substances/*adverse effects
MH  - *Health Status
MH  - Humans
MH  - Indians, North American/*statistics & numerical data
MH  - Male
MH  - Prevalence
MH  - Risk Factors
MH  - United States/epidemiology/ethnology
OTO - NOTNLM
OT  - American Indian/Alaska Native
OT  - Environmental epidemiology
OT  - Environmental justice
OT  - Health disparities
OT  - Toxicant exposure
EDAT- 2020/01/25 06:00
MHDA- 2021/08/24 06:00
CRDT- 2020/01/25 06:00
PHST- 2019/07/22 00:00 [received]
PHST- 2020/01/06 00:00 [accepted]
PHST- 2019/12/30 00:00 [revised]
PHST- 2020/01/25 06:00 [pubmed]
PHST- 2021/08/24 06:00 [medline]
PHST- 2020/01/25 06:00 [entrez]
AID - 10.1007/s40615-020-00700-2 [pii]
AID - 10.1007/s40615-020-00700-2 [doi]
PST - ppublish
SO  - J Racial Ethn Health Disparities. 2020 Aug;7(4):698-739. doi: 
      10.1007/s40615-020-00700-2. Epub 2020 Jan 23.