PMID- 31981998
OWN - NLM
STAT- MEDLINE
DCOM- 20210623
LR  - 20210623
IS  - 1872-6968 (Electronic)
IS  - 0303-8467 (Linking)
VI  - 191
DP  - 2020 Apr
TI  - Recurrent intracranial hemorrhage and cerebral venous sinus thrombosis: an 
      atypical case of Neuro-Behcet's Syndrome.
PG  - 105680
LID - S0303-8467(20)30023-8 [pii]
LID - 10.1016/j.clineuro.2020.105680 [doi]
AB  - We report the case of a 22-year-old man with an history of headaches, seizures, 
      cognitive impairment associated with recurrent intracranial hemorrhage (ICH), 
      acute ischemic stroke (AIS), worsened over the last eighteen months for a new 
      onset of uveitis and cerebral venous sinus thrombosis (CVST). After excluding 
      common causes of lobar ICH, and some rare ones according to the diagnostic 
      protocol proposed by Beuker et al, in the suspicion of Primary Angiitis of the 
      Central Nervous System (PACNS), the gradual development of a low-grade fever, a 
      cutaneous rash, and a papulopustular manifestation on lower back after 
      rachicentesis (pathergy phenomenon), allowed us to make a diagnosis of 
      Neuro-Behcet's Syndrome (NBS) without oral/genital aphthous ulcerations, 
      according to the International Study Group for Behcet's Disease classification 
      criteria for BD (ICBD).
CI  - Copyright (c) 2020 Elsevier B.V. All rights reserved.
FAU - Giammello, Fabrizio
AU  - Giammello F
AD  - Department of Clinical and Experimental Medicine, AOU Policlinico G. Martino, 
      University of Messina, Messina, Italy.
FAU - Dell'Aera, Cristina
AU  - Dell'Aera C
AD  - Department of Clinical and Experimental Medicine, AOU Policlinico G. Martino, 
      University of Messina, Messina, Italy.
FAU - Grillo, Francesco
AU  - Grillo F
AD  - Department of Clinical and Experimental Medicine, AOU Policlinico G. Martino, 
      University of Messina, Messina, Italy.
FAU - Cotroneo, Masina
AU  - Cotroneo M
AD  - Department of Clinical and Experimental Medicine, AOU Policlinico G. Martino, 
      University of Messina, Messina, Italy. Electronic address: 
      cotroneomasina@gmail.com.
FAU - Casella, Carmela
AU  - Casella C
AD  - Department of Clinical and Experimental Medicine, AOU Policlinico G. Martino, 
      University of Messina, Messina, Italy.
FAU - Fazio, Maria Carolina
AU  - Fazio MC
AD  - Department of Clinical and Experimental Medicine, AOU Policlinico G. Martino, 
      University of Messina, Messina, Italy.
FAU - La Spina, Paolino
AU  - La Spina P
AD  - Department of Clinical and Experimental Medicine, AOU Policlinico G. Martino, 
      University of Messina, Messina, Italy.
FAU - Francalanza, Isabella
AU  - Francalanza I
AD  - Department of Clinical and Experimental Medicine, AOU Policlinico G. Martino, 
      University of Messina, Messina, Italy.
FAU - Fiorenza, Alessia
AU  - Fiorenza A
AD  - Rheumatology Unit, University of Messina, Italy.
FAU - Toscano, Antonio
AU  - Toscano A
AD  - Department of Clinical and Experimental Medicine, AOU Policlinico G. Martino, 
      University of Messina, Messina, Italy.
FAU - Atzeni, Fabiola
AU  - Atzeni F
AD  - Rheumatology Unit, University of Messina, Italy.
FAU - Musolino, Rosa Fortunata
AU  - Musolino RF
AD  - Department of Clinical and Experimental Medicine, AOU Policlinico G. Martino, 
      University of Messina, Messina, Italy.
LA  - eng
PT  - Case Reports
DEP - 20200115
PL  - Netherlands
TA  - Clin Neurol Neurosurg
JT  - Clinical neurology and neurosurgery
JID - 7502039
RN  - Primary angiitis of the central nervous system
SB  - IM
MH  - Behcet Syndrome/*diagnosis/physiopathology
MH  - Cerebral Angiography
MH  - Cognitive Dysfunction/physiopathology
MH  - Headache/physiopathology
MH  - Humans
MH  - Intracranial Hemorrhages/*diagnostic imaging/physiopathology
MH  - Magnetic Resonance Angiography
MH  - Male
MH  - Recurrence
MH  - Seizures/physiopathology
MH  - Sinus Thrombosis, Intracranial/*diagnostic imaging/physiopathology
MH  - Vasculitis, Central Nervous System/*diagnosis/physiopathology
MH  - Young Adult
OTO - NOTNLM
OT  - CVST
OT  - Neurobehcet
OT  - PACNS
OT  - anti-TNF-alpha
EDAT- 2020/01/26 06:00
MHDA- 2021/06/24 06:00
CRDT- 2020/01/26 06:00
PHST- 2019/12/03 00:00 [received]
PHST- 2020/01/10 00:00 [revised]
PHST- 2020/01/13 00:00 [accepted]
PHST- 2020/01/26 06:00 [pubmed]
PHST- 2021/06/24 06:00 [medline]
PHST- 2020/01/26 06:00 [entrez]
AID - S0303-8467(20)30023-8 [pii]
AID - 10.1016/j.clineuro.2020.105680 [doi]
PST - ppublish
SO  - Clin Neurol Neurosurg. 2020 Apr;191:105680. doi: 10.1016/j.clineuro.2020.105680. 
      Epub 2020 Jan 15.