PMID- 31982265
OWN - NLM
STAT- MEDLINE
DCOM- 20200826
LR  - 20210602
IS  - 2174-2049 (Electronic)
IS  - 2174-2049 (Linking)
VI  - 38
IP  - 11
DP  - 2019 Nov
TI  - Myocardial deformation measures by cardiac magnetic resonance tissue tracking in 
      myocarditis: Relationship with systolic function and myocardial damage.
PG  - 767-776
LID - S0870-2551(20)30001-9 [pii]
LID - 10.1016/j.repc.2019.01.008 [doi]
AB  - INTRODUCTION AND OBJECTIVES: Cardiac magnetic resonance (CMR)-based tissue 
      tracking (TT) enables quantification of myocardial deformation and may be used as 
      an objective measure of myocardial involvement in myocarditis. The aims of this 
      study were to characterize myocardial deformation alterations in myocarditis and 
      to determine their relationship with the extent of late gadolinium enhancement 
      (LGE), regional wall motion abnormalities (WMA) and left ventricular ejection 
      fraction (LVEF). METHODS: A single-center, retrospective study was conducted by 
      identifying patients with clinically suspected myocarditis who underwent CMR 
      between 2012 and 2016. The myocardial deformation parameters were derived by TT 
      and correlated with LVEF, LGE and WMA, through Spearman's coefficient. RESULTS: A 
      cohort of 78 patients with myocarditis (aged 42.7+/-17.2 years) were included. CMR 
      characteristics including morphologic parameters (LVEF 52.1+/-12.8%), extent of WMA 
      (29.3+/-41.0%) and of LGE (30.5+/-21.8%) were assessed. Significant correlations were 
      found between all deformation parameters (strain, strain rate, velocity and 
      displacement) and both LVEF and extent of WMA. LGE was significantly correlated 
      with systolic radial strain (r: -0.32, p=0.004), strain rate (r: -0.27, p=0.017) 
      and displacement (r: -0.32, p=0.004) as well as systolic circumferential strain 
      (r: 0.28, p=0.013). CONCLUSION: Deformation parameters are an objective method 
      for quantification of myocardial function in myocarditis. They correlate with 
      LVEF, extent of WMA and degree of myocardial damage. Further studies are needed 
      to assess their incremental beneficial value for the diagnosis and risk 
      stratification of myocarditis.
CI  - Copyright (c) 2020 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier 
      Espana, S.L.U. All rights reserved.
FAU - Ruivo, Catarina
AU  - Ruivo C
AD  - Cardiology Department, Leiria Hospital Center, Portugal; Cardiology Department, 
      Vila Nova de Gaia Hospital Center, Portugal. Electronic address: 
      catarinaruivo10@gmail.com.
FAU - Vilela, Eduardo M
AU  - Vilela EM
AD  - Cardiology Department, Vila Nova de Gaia Hospital Center, Portugal.
FAU - Ladeiras-Lopes, Ricardo
AU  - Ladeiras-Lopes R
AD  - Cardiology Department, Vila Nova de Gaia Hospital Center, Portugal.
FAU - Faria, Rita
AU  - Faria R
AD  - Cardiology Department, Vila Nova de Gaia Hospital Center, Portugal.
FAU - Ferreira, Nuno
AU  - Ferreira N
AD  - Cardiology Department, Vila Nova de Gaia Hospital Center, Portugal.
FAU - Ribeiro, Vasco Gama
AU  - Ribeiro VG
AD  - Cardiology Department, Vila Nova de Gaia Hospital Center, Portugal.
LA  - eng
LA  - por
PT  - Journal Article
DEP - 20200122
PL  - Spain
TA  - Rev Port Cardiol (Engl Ed)
JT  - Revista portuguesa de cardiologia
JID - 101770878
SB  - IM
CIN - Rev Port Cardiol (Engl Ed). 2019 Nov;38(11):777-778. PMID: 31980216
MH  - Adult
MH  - Female
MH  - Heart/diagnostic imaging/physiopathology
MH  - Humans
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - *Myocarditis/diagnostic imaging/pathology/physiopathology
MH  - Myocardium/pathology
MH  - Systole/*physiology
OTO - NOTNLM
OT  - Cardiac magnetic resonance
OT  - Miocardite
OT  - Myocarditis
OT  - Ressonancia magnetica cardiaca
OT  - Tissue tracking
EDAT- 2020/01/27 06:00
MHDA- 2020/08/28 06:00
CRDT- 2020/01/27 06:00
PHST- 2018/09/24 00:00 [received]
PHST- 2018/12/29 00:00 [revised]
PHST- 2019/01/13 00:00 [accepted]
PHST- 2020/01/27 06:00 [pubmed]
PHST- 2020/08/28 06:00 [medline]
PHST- 2020/01/27 06:00 [entrez]
AID - S0870-2551(20)30001-9 [pii]
AID - 10.1016/j.repc.2019.01.008 [doi]
PST - ppublish
SO  - Rev Port Cardiol (Engl Ed). 2019 Nov;38(11):767-776. doi: 
      10.1016/j.repc.2019.01.008. Epub 2020 Jan 22.