PMID- 3198238 OWN - NLM STAT- MEDLINE DCOM- 19890118 LR - 20151119 IS - 0300-5038 (Print) IS - 0300-5038 (Linking) IP - 89 DP - 1988 TI - N-nitrosoproline excretion in patients with gastric lesions and in a control population. PG - 97-101 AB - N-Nitrosoproline (NPRO) excretion was measured in a group of hospital in-patients who were identified as either bearing gastric lesions or having apparently healthy stomachs. NPRO was assayed in background 24-h urine samples and then in urines collected after loading doses of nitrate and proline. The presence of gastric lesions was associated with altered gastric juice pH and nitrite concentration, but not with NPRO excretion. The significance of NPRO excretion as a marker of endogenous nitrosation is dependent on the interpretation of this result. FAU - Knight, T M AU - Knight TM AD - Imperial Cancer Research Fund, Radcliffe Infirmary, Oxford, UK. FAU - Forman, D AU - Forman D FAU - Leach, S AU - Leach S FAU - Packer, P AU - Packer P FAU - Vindigni, C AU - Vindigni C FAU - Minacci, C AU - Minacci C FAU - Lorenzini, L AU - Lorenzini L FAU - Tosi, P AU - Tosi P FAU - Frosini, G AU - Frosini G FAU - Marini, M AU - Marini M AU - et al. LA - eng PT - Journal Article PL - France TA - IARC Sci Publ JT - IARC scientific publications JID - 8009542 RN - 0 (Nitrates) RN - 0 (Nitrites) RN - 0 (Nitrosamines) RN - F8MI03SGY0 (nitrosoproline) SB - IM MH - Adult MH - Aged MH - Gastric Acidity Determination MH - Gastric Juice/analysis MH - Humans MH - Middle Aged MH - Nitrates/analysis MH - Nitrites/analysis MH - Nitrosamines/*urine MH - Stomach Diseases/*urine EDAT- 1988/01/01 00:00 MHDA- 1988/01/01 00:01 CRDT- 1988/01/01 00:00 PHST- 1988/01/01 00:00 [pubmed] PHST- 1988/01/01 00:01 [medline] PHST- 1988/01/01 00:00 [entrez] PST - ppublish SO - IARC Sci Publ. 1988;(89):97-101.