PMID- 31984147
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2090-6889 (Print)
IS  - 2090-6897 (Electronic)
IS  - 2090-6897 (Linking)
VI  - 2020
DP  - 2020
TI  - Ankylosing Spondyloarthritis Resulting Severe Aortic Insufficiency and Aortitis: 
      Exacerbation of Ankylosing Spondyloarthritis and Stenosis of the Main Left 
      Coronary Artery after Mechanical Aortic Valve Implantation with Cardiopulmonary 
      Bypass.
PG  - 9538527
LID - 10.1155/2020/9538527 [doi]
LID - 9538527
AB  - Ankylosing spondyloarthritis (AS) is a chronic inflammatory rheumatic disease, 
      strongly related to human leukocyte antigen (HLA)-B27. Cardiac involvement in AS 
      manifests in 2 to 10% of patients as aortic insufficiency, aortitis, mitral valve 
      fibrosis, or disturbance in the conduction of the heart. In this article, we 
      present a case of a 49-year-old male patient with AS, who was referred to our 
      medical institution for elective aortic valve surgery because of severe aortic 
      regurgitation. The histological findings revealed fibrosing endocarditis of 
      aortic valve and nonspecific aortitis of aortic root. Late postoperatively, we 
      observed exacerbation of AS and narrowing of the main left coronary artery (LAD). 
      Our case highlights the importance of proper treatment of AS before and after 
      cardiac surgery. Furthermore, in this case, we suspect association between 
      cardiopulmonary bypass, activity of AS, and coronary artery disease.
CI  - Copyright (c) 2020 Agne Balciunaite et al.
FAU - Balciunaite, Agne
AU  - Balciunaite A
AD  - Department of Cardiac, Thoracic and Vascular Surgery, Medical Academy, Lithuanian 
      University of Health Sciences, Kaunas, Lithuania.
FAU - Budrikis, Algimantas
AU  - Budrikis A
AD  - Department of Cardiac, Thoracic and Vascular Surgery, Medical Academy, Lithuanian 
      University of Health Sciences, Kaunas, Lithuania.
FAU - Rumbinaite, Egle
AU  - Rumbinaite E
AUID- ORCID: 0000-0003-2657-5745
AD  - Department of Cardiology, Medical Academy, Lithuanian University of Health 
      Sciences, Kaunas, Lithuania.
FAU - Sabaliauskiene, Jurgita
AU  - Sabaliauskiene J
AD  - Department of Rheumatology, Lithuanian University of Health Sciences, Kaunas, 
      Lithuania.
FAU - Patamsyte, Vaiva
AU  - Patamsyte V
AUID- ORCID: 0000-0002-2270-1276
AD  - Institute of Cardiology of the Medical Academy, Lithuanian University of Health 
      Sciences, Kaunas, Lithuania.
FAU - Lesauskaite, Vaiva
AU  - Lesauskaite V
AUID- ORCID: 0000-0001-5674-2490
AD  - Institute of Cardiology of the Medical Academy, Lithuanian University of Health 
      Sciences, Kaunas, Lithuania.
LA  - eng
PT  - Case Reports
DEP - 20200103
PL  - United States
TA  - Case Rep Rheumatol
JT  - Case reports in rheumatology
JID - 101585353
PMC - PMC6964718
COIS- The authors declare that they have no conflicts of interest.
EDAT- 2020/01/28 06:00
MHDA- 2020/01/28 06:01
PMCR- 2020/01/03
CRDT- 2020/01/28 06:00
PHST- 2019/10/03 00:00 [received]
PHST- 2019/12/17 00:00 [accepted]
PHST- 2020/01/28 06:00 [entrez]
PHST- 2020/01/28 06:00 [pubmed]
PHST- 2020/01/28 06:01 [medline]
PHST- 2020/01/03 00:00 [pmc-release]
AID - 10.1155/2020/9538527 [doi]
PST - epublish
SO  - Case Rep Rheumatol. 2020 Jan 3;2020:9538527. doi: 10.1155/2020/9538527. 
      eCollection 2020.