PMID- 31985181
OWN - NLM
STAT- MEDLINE
DCOM- 20210128
LR  - 20210128
IS  - 1756-185X (Electronic)
IS  - 1756-1841 (Linking)
VI  - 23
IP  - 4
DP  - 2020 Apr
TI  - Ultrasonographic evaluation of Achilles tendon: Is there any difference between 
      ankylosing spondylitis, non-radiographic axial spondyloarthropathy and controls?
PG  - 511-519
LID - 10.1111/1756-185X.13796 [doi]
AB  - PURPOSE: The aim is to evaluate Achilles tendon enthesopathy with ultrasound (US) 
      in ankylosing spondylitis (AS) and non-radiographic axial SpA (nr-axSpA) patients 
      and controls, and compare these groups in terms of associations between disease 
      activity parameters and ultrasonographic Achilles enthesitis signs. METHODS: A 
      total of 24 AS and 20 nr-axSpA patients fulfilling the Assessment in 
      Spondyloarthritis International Working Group criteria for axSpA and 30 controls 
      were enrolled. Demographic characteristics, erythrocyte sedimentation rate, 
      C-reactive protein (CRP), human leukocyte antigen (HLA)-B27, Bath AS Disease 
      Activity Index, Bath AS Functional Index, Bath AS Metrology Index, Maastricht AS 
      Enthesitis Score (MASES), AS Disease Activity Score-CRP, modified Stoke AS Spine 
      Score (m-SASSS) scores and ultrasonographic findings were noted. RESULTS: HLA-B27 
      positivity, extra-articular and peripheral involvement, disease activity, 
      functional status, mean m-SASSS, ultrasonographic gray scale (GS) and total 
      scores were similar between AS and nr-axSpA groups. In GS, tendon echotexture 
      scores were significantly different across all groups (0.812 +/- 0.384 in AS, 
      0.575 +/- 0.466 in nr-axSpA, 0.017 +/- 0.091 in controls; P < .001). Entheseal 
      calcification scores were similar in AS and nr-axSpA patients, and higher than 
      controls (P = .001). Bone profile scores were similar in patients with AS and 
      nr-axSpA, and higher than controls (P = .010). When the correlations between US 
      findings and disease activity and functional status were considered, power 
      Doppler US (PDUS) and MASES total scores were positively correlated in the AS 
      group (P = .045; r = .41). CONCLUSION: AS and nr-axSpA patients were found to be 
      similar in various clinical, functional, and US findings indicating that these 2 
      entities are different phenotypic reflections of the same disease spectrum. The 
      positive correlation between PDUS and MASES scores in AS patients substantiate 
      the performance of MASES in evaluation of entheseal activity.
CI  - (c) 2020 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons 
      Australia, Ltd.
FAU - Vahidfar, Shahla
AU  - Vahidfar S
AUID- ORCID: 0000-0002-4886-4946
AD  - Department of PRM, Ankara University School of Medicine, Ankara, Turkey.
FAU - Sunar, Ismihan
AU  - Sunar I
AUID- ORCID: 0000-0002-4435-5677
AD  - Rheumatology Department, Department of PRM, Ankara University School of Medicine, 
      Ankara, Turkey.
FAU - Ataman, Sebnem
AU  - Ataman S
AD  - Rheumatology Department, Department of PRM, Ankara University School of Medicine, 
      Ankara, Turkey.
FAU - Yilmaz, Gurkan
AU  - Yilmaz G
AD  - Rheumatology Department, Department of PRM, Ankara University School of Medicine, 
      Ankara, Turkey.
FAU - Azarabadi, Javid M
AU  - Azarabadi JM
AD  - Department of Orthopaedia, Baskent University School of Medicine, Baskent, 
      Turkey.
FAU - Bolukbasi, Ayse
AU  - Bolukbasi A
AD  - Department of PRM, Ankara University School of Medicine, Ankara, Turkey.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20200126
PL  - England
TA  - Int J Rheum Dis
JT  - International journal of rheumatic diseases
JID - 101474930
SB  - IM
MH  - Achilles Tendon/*diagnostic imaging
MH  - Adult
MH  - Case-Control Studies
MH  - Diagnosis, Differential
MH  - Enthesopathy/*diagnostic imaging
MH  - Female
MH  - Humans
MH  - Male
MH  - Phenotype
MH  - Predictive Value of Tests
MH  - Spondylarthropathies/*diagnostic imaging
MH  - Spondylitis, Ankylosing/*diagnostic imaging
MH  - *Ultrasonography, Doppler
MH  - Young Adult
OTO - NOTNLM
OT  - achilles
OT  - ankylosing spondylitis
OT  - enthesitis
OT  - non-radiographic axial spondyloarthritis
OT  - ultrasound
EDAT- 2020/01/28 06:00
MHDA- 2021/01/29 06:00
CRDT- 2020/01/28 06:00
PHST- 2019/09/10 00:00 [received]
PHST- 2019/12/09 00:00 [revised]
PHST- 2019/12/29 00:00 [accepted]
PHST- 2020/01/28 06:00 [pubmed]
PHST- 2021/01/29 06:00 [medline]
PHST- 2020/01/28 06:00 [entrez]
AID - 10.1111/1756-185X.13796 [doi]
PST - ppublish
SO  - Int J Rheum Dis. 2020 Apr;23(4):511-519. doi: 10.1111/1756-185X.13796. Epub 2020 
      Jan 26.