PMID- 31985701
OWN - NLM
STAT- MEDLINE
DCOM- 20210830
LR  - 20210830
IS  - 1550-5049 (Electronic)
IS  - 0889-4655 (Linking)
VI  - 35
IP  - 2
DP  - 2020 Mar/Apr
TI  - Prediction of Heart Failure Symptoms and Health-Related Quality of Life at 12 
      Months From Baseline Modifiable Factors in Patients With Heart Failure.
PG  - 116-125
LID - 10.1097/JCN.0000000000000642 [doi]
AB  - BACKGROUND: In patients with heart failure (HF), good health-related quality of 
      life (HRQOL) is as valuable as, or more valuable than, longer survival. However, 
      HRQOL is remarkably poor, and HF symptoms are strongly associated with poor 
      HRQOL. Yet, the multidimensional, modifiable predictors have been rarely 
      examined. OBJECTIVE: The aim of this study was to examine the baseline 
      psychosocial, behavioral, and physical predictors of HF symptoms and HRQOL at 12 
      months and the mediator effect of HF symptoms in the relationship between 
      depressive symptoms and HRQOL. METHODS: We collected data from 94 patients with 
      HF (mean +/- SD age, 58 +/- 14 years). Data included sample characteristics, 
      depressive symptoms, perceived control, social support, New York Heart 
      Association (NYHA) functional class, medication adherence, sodium intake, 
      self-care management, and HF symptoms at baseline, as well as HF symptoms and 
      HRQOL at 12 months. Multiple regression analyses were performed to address the 
      purpose. RESULTS: Baseline depressive symptoms (P < .001), medication adherence 
      (P = .010), sodium intake (P = .032), and NYHA functional class (P = .040) 
      significantly predicted 12-month HF symptoms, controlling for covariates (F = 
      7.363, R = 47%, P < .001). Baseline medication adherence (P = .001), NYHA 
      functional class (P < .001), and HF symptoms (P = .013) significantly predicted 
      12-month HRQOL (F = 10.701, R = 59%, P < .001). Baseline HF symptoms fully 
      mediated the relationship between baseline depressive symptoms and 12-month 
      HRQOL. CONCLUSION: Symptoms of HF and HRQOL could be improved by targeting 
      multidimensional, modifiable predictors, such as self-care, depressive symptoms, 
      and NYHA functional class.
FAU - Heo, Seongkum
AU  - Heo S
FAU - Moser, Debra K
AU  - Moser DK
FAU - Lennie, Terry A
AU  - Lennie TA
FAU - Fischer, Mary
AU  - Fischer M
FAU - Kim, JinShil
AU  - Kim J
FAU - Walsh, Mary N
AU  - Walsh MN
FAU - Ounpraseuth, Songthip
AU  - Ounpraseuth S
FAU - Turrise, Stephanie
AU  - Turrise S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Cardiovasc Nurs
JT  - The Journal of cardiovascular nursing
JID - 8703516
SB  - IM
MH  - Adult
MH  - Aged
MH  - Correlation of Data
MH  - Female
MH  - Forecasting
MH  - Heart Failure/*diagnosis
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - *Quality of Life
MH  - Symptom Assessment
MH  - Time Factors
EDAT- 2020/01/28 06:00
MHDA- 2021/08/31 06:00
CRDT- 2020/01/28 06:00
PHST- 2020/01/28 06:00 [pubmed]
PHST- 2021/08/31 06:00 [medline]
PHST- 2020/01/28 06:00 [entrez]
AID - 00005082-202003000-00005 [pii]
AID - 10.1097/JCN.0000000000000642 [doi]
PST - ppublish
SO  - J Cardiovasc Nurs. 2020 Mar/Apr;35(2):116-125. doi: 10.1097/JCN.0000000000000642.