PMID- 31986310 OWN - NLM STAT- MEDLINE DCOM- 20200413 LR - 20200413 IS - 1872-9142 (Electronic) IS - 0161-5890 (Linking) VI - 119 DP - 2020 Mar TI - Dendritic cell development: A personal historical perspective. PG - 64-68 LID - S0161-5890(19)30650-9 [pii] LID - 10.1016/j.molimm.2019.12.016 [doi] AB - Dendritic cells(DCs) were once considered as a single cell type closely related developmentally to macrophages. Now we recognise several subtypes of DCs and have outlined several different pathways that potentially lead to their development. This article outlines some of the research findings that led to these changes in perspective, from the point of view of one of the participants. CI - Copyright (c) 2019 Elsevier Ltd. All rights reserved. FAU - Shortman, Ken AU - Shortman K AD - The Walter and Eliza Hall Institute, Melbourne, Australia. Electronic address: shortman@wehi.edu.au. LA - eng PT - Historical Article PT - Journal Article PT - Review DEP - 20200124 PL - England TA - Mol Immunol JT - Molecular immunology JID - 7905289 RN - 0 (Cytokines) SB - IM MH - Animals MH - Bone Marrow Cells/physiology MH - Cell Biology/*history MH - Cell Differentiation/physiology MH - Cytokines/physiology MH - Dendritic Cells/*physiology MH - History, 20th Century MH - History, 21st Century MH - Humans MH - Thymus Gland/cytology EDAT- 2020/01/28 06:00 MHDA- 2020/04/14 06:00 CRDT- 2020/01/28 06:00 PHST- 2019/09/18 00:00 [received] PHST- 2019/12/02 00:00 [revised] PHST- 2019/12/20 00:00 [accepted] PHST- 2020/01/28 06:00 [pubmed] PHST- 2020/04/14 06:00 [medline] PHST- 2020/01/28 06:00 [entrez] AID - S0161-5890(19)30650-9 [pii] AID - 10.1016/j.molimm.2019.12.016 [doi] PST - ppublish SO - Mol Immunol. 2020 Mar;119:64-68. doi: 10.1016/j.molimm.2019.12.016. Epub 2020 Jan 24.