PMID- 31987165
OWN - NLM
STAT- MEDLINE
DCOM- 20200922
LR  - 20200922
IS  - 1873-3573 (Electronic)
IS  - 0039-9140 (Linking)
VI  - 210
DP  - 2020 Apr 1
TI  - Novel PEP-PAN@PSF rods extraction of EDCs in environmental water, sediment, and 
      fish homogenate followed by pre-column derivatization and UHPLC-MS/MS detection.
PG  - 120661
LID - S0039-9140(19)31294-9 [pii]
LID - 10.1016/j.talanta.2019.120661 [doi]
AB  - In the study, novel polysulfone hollow fiber membrane (PSF) supported polar 
      enhanced phase (PEP) particles-polyacrylonitrile (PAN) polymer thin-film rods 
      (PEP-PAN@PSF rods) were developed for the extraction of five steroidal endocrine 
      disrupting chemicals (EDCs) (estrone (E1), estradiol (E2), estriol (E3), 
      ethinyloestradiol (EE2), 2-methoxyestradiol (2ME2)) and four phenolic EDCs 
      (bisphenol A (BPA), hexestrol (HEX), diethylstilbestrol (DES), dienestrol (DE)) 
      in environmental water, sediment, and fish muscle homogenates, followed by 
      pre-column derivatization and ultra-high performance liquid chromatography 
      coupled with tandem mass spectrometry (UHPLC-MS/MS). The traditional preparation 
      method for thin-film rods was improved by introducing a supporting membrane PSF 
      between the external thin-film coating and the internal bare rod, avoiding the 
      conventional pre-corrosion by strong acid/base. The commercial PEP prepared rods 
      showed competitive capacity for both polar and nonpolar EDCs. In addition, 
      pre-column derivatization with dansyl chloride (DNS-Cl) was adopted for the 
      phenolic analytes prior to UHPLC-MS/MS detection, leading to a significant 
      enhancement of sensitivity via analyzing the dansylated derivatives under 
      positive electrospray ionization (ESI) mode instead of the analytes under 
      negative ESI mode. The protocol was validated in four matrices including 
      environmental water, sediment and two fish species. No matrix effects were 
      observed in four matrices. The limits of detection (LODs) for the analytes were 
      in the range of 0.002-0.072 mug L(-1) for environmental water, 
      0.032-0.734 ng g(-1) for sediment, and 0.011-0.435 ng g(-1) for two fish species, 
      respectively. Appropriate linearity was observed for all the analytes with 
      correlation coefficients (R(2)) above 0.997. The intra-day trueness of the 
      approach at low, medium and high levels was in the range of 86.6-116.1% with 
      relative standard deviations (RSDs) lower than 15.4%. And the inter-day trueness 
      was in the range of 84.6-114.8% with RSDs lower than 16.3%. The proposed method 
      was successfully applied for the analysis of nine EDCs in environmental water, 
      sediment, and fish muscle homogenates.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Bonfoh, Sabour Issofa
AU  - Bonfoh SI
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China.
FAU - Li, Dan
AU  - Li D
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China.
FAU - Xiong, Xiang
AU  - Xiong X
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China.
FAU - Du, Zhifeng
AU  - Du Z
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China.
FAU - Xiong, Chaomei
AU  - Xiong C
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China. Electronic 
      address: cmxiong2002@hust.edu.cn.
FAU - Jiang, Hongliang
AU  - Jiang H
AD  - Department of Pharmaceutical Analysis, School of Pharmacy, Tongji Medical 
      College, Huazhong University of Science and Technology, PR China.
LA  - eng
PT  - Journal Article
DEP - 20191221
PL  - Netherlands
TA  - Talanta
JT  - Talanta
JID - 2984816R
RN  - 0 (Acrylic Resins)
RN  - 0 (Polymers)
RN  - 0 (Sulfones)
RN  - 0 (Water Pollutants, Chemical)
RN  - 25014-41-9 (polyacrylonitrile)
RN  - 25135-51-7 (polysulfone P 1700)
RN  - 2DI9HA706A (Estrone)
RN  - 423D2T571U (Ethinyl Estradiol)
RN  - 4TI98Z838E (Estradiol)
RN  - 6I2QW73SR5 (2-Methoxyestradiol)
RN  - FB33469R8E (Estriol)
SB  - IM
MH  - 2-Methoxyestradiol/analysis
MH  - Acrylic Resins/*chemistry
MH  - Animals
MH  - Chromatography, High Pressure Liquid
MH  - *Environmental Monitoring
MH  - Estradiol/analysis
MH  - Estriol/analysis
MH  - Estrone/analysis
MH  - Ethinyl Estradiol/analysis
MH  - Fishes
MH  - Geologic Sediments/*analysis
MH  - Polymers/*chemistry
MH  - Sulfones/*chemistry
MH  - Tandem Mass Spectrometry
MH  - Water Pollutants, Chemical/*analysis
OTO - NOTNLM
OT  - Endocrine disrupting chemicals (EDCs)
OT  - Environmental water
OT  - Fish
OT  - PEP-PAN@PSF rods
OT  - Sediment
OT  - Thin-film microextraction
COIS- Declaration of competing interest The authors declared that they have no 
      conflicts of interest to this work.
EDAT- 2020/01/29 06:00
MHDA- 2020/09/23 06:00
CRDT- 2020/01/29 06:00
PHST- 2019/08/01 00:00 [received]
PHST- 2019/11/16 00:00 [revised]
PHST- 2019/12/19 00:00 [accepted]
PHST- 2020/01/29 06:00 [entrez]
PHST- 2020/01/29 06:00 [pubmed]
PHST- 2020/09/23 06:00 [medline]
AID - S0039-9140(19)31294-9 [pii]
AID - 10.1016/j.talanta.2019.120661 [doi]
PST - ppublish
SO  - Talanta. 2020 Apr 1;210:120661. doi: 10.1016/j.talanta.2019.120661. Epub 2019 Dec 
      21.