PMID- 31992448
OWN - NLM
STAT- MEDLINE
DCOM- 20210111
LR  - 20210111
IS  - 1618-0372 (Electronic)
IS  - 0065-1281 (Linking)
VI  - 122
IP  - 3
DP  - 2020 Apr
TI  - Inhibition of the migration of MCP-1 positive cells by icing applied soon after 
      crush injury to rat skeletal muscle.
PG  - 151511
LID - S0065-1281(20)30010-6 [pii]
LID - 10.1016/j.acthis.2020.151511 [doi]
AB  - Migration of the macrophages to the injured site soon after the skeletal muscle 
      injury is crucial for subsequent regeneration of the muscle fibers. The Monocyte 
      chemoattractant protein-1 (MCP-1) is important chemokine for regulating migration 
      of the monocytes/macrophages. Earlier reports have discussed that icing applied 
      soon after muscle crush injury retards muscle regeneration through retardation of 
      macrophage migration. The MCP-1+ cells and neutrophils might promote the 
      migration of the macrophages. To test the hypothesis that icing soon after the 
      skeletal muscle injury affects MCP-1+ cells and neutrophils, we examined the 
      effect of icing on MCP-1+ cells and neutrophils after crush injury to skeletal 
      muscle in rats. Owing to the icing application for 20 min soon after the injury, 
      accumulation of the macrophages was inhibited until 12 h after injury. Numbers of 
      the neutrophils at 3 h after the injury and the MCP-1+ cells at 6 h and later 
      after the injury in the icing group were significantly lower than those in the 
      non-icing group, suggesting that these phenomena contribute to the retardation of 
      macrophage migration.
CI  - Copyright (c) 2020 Elsevier GmbH. All rights reserved.
FAU - Miyakawa, Motoi
AU  - Miyakawa M
AD  - Department of Rehabilitation Sciences, Kobe University Graduate School of Health 
      Sciences, Kobe, Japan.
FAU - Kawashima, Masato
AU  - Kawashima M
AD  - Department of Rehabilitation Sciences, Kobe University Graduate School of Health 
      Sciences, Kobe, Japan.
FAU - Haba, Daijiro
AU  - Haba D
AD  - Department of Rehabilitation Sciences, Kobe University Graduate School of Health 
      Sciences, Kobe, Japan.
FAU - Sugiyama, Megumi
AU  - Sugiyama M
AD  - Department of Rehabilitation Sciences, Kobe University Graduate School of Health 
      Sciences, Kobe, Japan.
FAU - Taniguchi, Kaho
AU  - Taniguchi K
AD  - Faculty of Health Sciences, Kobe University School of Medicine, Kobe, Japan.
FAU - Arakawa, Takamitsu
AU  - Arakawa T
AD  - Department of Rehabilitation Sciences, Kobe University Graduate School of Health 
      Sciences, Kobe, Japan. Electronic address: arakawa@people.kobe-u.ac.jp.
LA  - eng
PT  - Journal Article
DEP - 20200125
PL  - Germany
TA  - Acta Histochem
JT  - Acta histochemica
JID - 0370320
RN  - 0 (Antigens, CD)
RN  - 0 (Antigens, Differentiation, Myelomonocytic)
RN  - 0 (CD68 antigen, human)
RN  - 0 (Ccl2 protein, rat)
RN  - 0 (Chemokine CCL2)
RN  - 0 (Ice)
SB  - IM
MH  - Animals
MH  - Antigens, CD
MH  - Antigens, Differentiation, Myelomonocytic
MH  - *Cell Movement
MH  - Chemokine CCL2/*metabolism
MH  - Crush Injuries/*pathology
MH  - Ice
MH  - Immunohistochemistry
MH  - Male
MH  - Muscle Fibers, Skeletal/pathology
MH  - Muscle, Skeletal/*injuries/pathology
MH  - Neutrophils
MH  - Rats
MH  - Rats, Wistar
MH  - Regeneration
OTO - NOTNLM
OT  - MCP-1
OT  - Macrophage
OT  - Migration
OT  - Muscle regeneration
OT  - Neutrophil
EDAT- 2020/01/30 06:00
MHDA- 2021/01/12 06:00
CRDT- 2020/01/30 06:00
PHST- 2019/07/18 00:00 [received]
PHST- 2019/12/22 00:00 [revised]
PHST- 2020/01/17 00:00 [accepted]
PHST- 2020/01/30 06:00 [pubmed]
PHST- 2021/01/12 06:00 [medline]
PHST- 2020/01/30 06:00 [entrez]
AID - S0065-1281(20)30010-6 [pii]
AID - 10.1016/j.acthis.2020.151511 [doi]
PST - ppublish
SO  - Acta Histochem. 2020 Apr;122(3):151511. doi: 10.1016/j.acthis.2020.151511. Epub 
      2020 Jan 25.