PMID- 31997714
OWN - NLM
STAT- MEDLINE
DCOM- 20200720
LR  - 20221207
IS  - 1545-1550 (Electronic)
IS  - 1526-6028 (Linking)
VI  - 27
IP  - 2
DP  - 2020 Apr
TI  - Outcomes of Pedal Artery Angioplasty Are Independent of the Severity of 
      Inframalleolar Disease: A Subanalysis of the Multicenter RENDEZVOUS Registry.
PG  - 186-193
LID - 10.1177/1526602820901838 [doi]
AB  - Purpose: To examine the efficacy of pedal artery angioplasty (PAA) for chronic 
      limb-threatening ischemia (CLTI) according to the severity of inframalleolar 
      disease. Methods: In total, 257 consecutive CLTI patients (mean age 73.2 years; 
      175 men) with de novo infrapopliteal and inframalleolar artery disease were 
      enrolled from the retrospective RENDEZVOUS registry. Inframalleolar artery 
      disease was classified as moderate (Kawarada type 2, 144 patients) or severe 
      (Kawarada type 3, 113 patients). PAA was performed in 140 patients: 66 (45.8%) 
      with moderate disease and 74 (65.5%) with severe disease. The remaining 117 
      patients (78 with moderate disease and 39 with severe disease) underwent 
      interventions that did not include PAA. The primary outcomes were the wound 
      healing and limb salvage rates at 12 months after the initial treatment. The 
      outcomes of the PAA and no-PAA groups were examined to determine any correlation 
      between treatment efficacy and baseline disease severity. Results: The success 
      rates of PAA among the patients with moderate and severe inframalleolar disease 
      were 89.4% and 87.8%, respectively (p=0.683). The wound healing rate at 12 months 
      was significantly higher in the PAA group than in the no-PAA group regardless of 
      the severity of inframalleolar disease [moderate: 58.8% vs 40.0% (p=0.049); 
      severe: 59.6% vs 33.2% (p=0.021), respectively]. The worst limb salvage rate 
      (76.9%) was seen among patients in the no-PAA group with severe inframalleolar 
      disease (no-PAA/moderate: 94.8%; PAA/moderate: 90.9%; and PAA/severe: 87.8%, 
      p=0.028). Conclusion: PAA improves the wound healing rate of patients with CLTI 
      regardless of the severity of inframalleolar disease. This treatment modality 
      also might improve limb salvage rates in patients with severe inframalleolar 
      disease affecting both the anterior and posterior pedal circulations.
FAU - Tsubakimoto, Yoshinori
AU  - Tsubakimoto Y
AUID- ORCID: 0000-0003-0785-7835
AD  - Department of Cardiology, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan.
FAU - Nakama, Tatsuya
AU  - Nakama T
AUID- ORCID: 0000-0001-9107-6438
AD  - Department of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, Chiba, 
      Japan.
FAU - Kamoi, Daisuke
AU  - Kamoi D
AD  - Nagoya EVT Clinic, Nagoya, Japan.
FAU - Andoh, Hiroshi
AU  - Andoh H
AD  - Department of Cardiology, Kasukabe Chuo General Hospital, Saitama, Japan.
FAU - Urasawa, Kazushi
AU  - Urasawa K
AD  - Cardiovascular Center, Tokeidai Memorial Hospital, Sapporo, Japan.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
DEP - 20200130
PL  - United States
TA  - J Endovasc Ther
JT  - Journal of endovascular therapy : an official journal of the International 
      Society of Endovascular Specialists
JID - 100896915
SB  - IM
CIN - J Endovasc Ther. 2020 Apr;27(2):194-197. PMID: 32096453
MH  - Aged
MH  - Aged, 80 and over
MH  - Amputation, Surgical
MH  - *Angioplasty, Balloon/adverse effects/instrumentation
MH  - Chronic Disease
MH  - Female
MH  - Humans
MH  - Ischemia/diagnostic imaging/physiopathology/*therapy
MH  - Japan
MH  - Limb Salvage
MH  - Lower Extremity/*blood supply
MH  - Male
MH  - Middle Aged
MH  - Peripheral Arterial Disease/diagnostic imaging/physiopathology/*therapy
MH  - Registries
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Stents
MH  - Time Factors
MH  - Treatment Outcome
MH  - Wound Healing
OTO - NOTNLM
OT  - chronic limb-threatening ischemia
OT  - endovascular treatment
OT  - inframalleolar artery disease
OT  - limb salvage
OT  - pedal artery intervention
OT  - wound healing
EDAT- 2020/01/31 06:00
MHDA- 2020/07/21 06:00
CRDT- 2020/01/31 06:00
PHST- 2020/01/31 06:00 [pubmed]
PHST- 2020/07/21 06:00 [medline]
PHST- 2020/01/31 06:00 [entrez]
AID - 10.1177/1526602820901838 [doi]
PST - ppublish
SO  - J Endovasc Ther. 2020 Apr;27(2):186-193. doi: 10.1177/1526602820901838. Epub 2020 
      Jan 30.