PMID- 31999615
OWN - NLM
STAT- MEDLINE
DCOM- 20210719
LR  - 20210719
IS  - 2468-7812 (Electronic)
IS  - 2468-7812 (Linking)
VI  - 46
DP  - 2020 Apr
TI  - What is the minimal important difference of pain intensity, mandibular function, 
      and headache impact in patients with temporomandibular disorders? Clinical 
      significance analysis of a randomized controlled trial.
PG  - 102108
LID - S2468-7812(19)30011-6 [pii]
LID - 10.1016/j.msksp.2020.102108 [doi]
AB  - BACKGROUND: There are insufficient studies providing Minimal Clinically Important 
      Difference (MCID) for outcomes related to temporomandibular disorders (TMD). 
      OBJECTIVES: (1) To provide the MCID of outcomes related to TMD using the Global 
      Rating of Change Scale (GRCS) as an anchor. (2) To verify which outcomes can 
      predict a moderate or large response to the treatment. STUDY DESIGN: Secondary 
      analysis of a randomized controlled trial in subjects with TMD. METHODS: 
      Sixty-one women with TMD were divided into intervention and control groups. 
      Visual Analogue Scale (VAS), Headache Impact Test (HIT-6), pressure pain 
      thresholds (PPTs) of masticatory muscles, Mandibular Function Impairment 
      Questionnaire (MFIQ), and Craniocervical Flexion Test (CCFT) were collected at 
      baseline and 5-weeks follow-up. RESULTS: Participants were divided based on their 
      response to the treatment, according to the GRCS. MCID values were provided for 
      subjects that moderately or largely improved to the treatment. MCID was between 0 
      and 1.90 for orofacial pain, around 2 points for the MFIQ, between 3 and 6.26 
      points for the HIT-6, around 0.2 kg/cm2 for the PPTs on masticatory muscles, 
      around 2.5 mm for MMO and between 60 and 68 points for CCFT. Orofacial pain and 
      HIT-6 were the most discriminative variables at determining whether patients 
      would largely/moderately improve or would not improve after treatment. 
      CONCLUSIONS: The values of MCID could be used as guidance for both clinical 
      practice and research. Pain intensity and headache impact were the most 
      predictive outcomes for improvement of the general health status of women with 
      TMD.
CI  - Copyright (c) 2020 Elsevier Ltd. All rights reserved.
FAU - Calixtre, Leticia Bojikian
AU  - Calixtre LB
AD  - Laboratory of Clinical and Occupational Kinesiology (LACO), Department of 
      Physical Therapy, Federal University of Sao Carlos (UFSCar), Sao Carlos, SP, 
      Brazil. Electronic address: lecalixtre@hotmail.com.
FAU - Oliveira, Ana Beatriz
AU  - Oliveira AB
AD  - Laboratory of Clinical and Occupational Kinesiology (LACO), Department of 
      Physical Therapy, Federal University of Sao Carlos (UFSCar), Sao Carlos, SP, 
      Brazil.
FAU - Alburquerque-Sendin, Francisco
AU  - Alburquerque-Sendin F
AD  - Department of Sociosanitary Sciences, Radiology and Physical Medicine, University 
      of Cordoba, GC05 Systemic and Chronic Inflammatory Autoimmune Diseases of the 
      Locomotor System and Connective Tissue, Instituto Maimonides de Investigacion 
      Biomedica de Cordoba (IMIBIC), Cordoba, Spain.
FAU - Armijo-Olivo, Susan
AU  - Armijo-Olivo S
AD  - University of Applied Sciences, Faculty of Business and Social Sciences, 
      Osnabruck, Germany; Faculty of Rehabilitation Medicine/Faculty of Medicine and 
      Dentistry, Department of Physical Therapy, University of Alberta, Edmonton, 
      Canada.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20200111
PL  - Netherlands
TA  - Musculoskelet Sci Pract
JT  - Musculoskeletal science & practice
JID - 101692753
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Exercise Therapy
MH  - Female
MH  - Headache/*etiology/*therapy
MH  - Humans
MH  - *Minimal Clinically Important Difference
MH  - Musculoskeletal Manipulations
MH  - Pain Management/*methods
MH  - *Pain Measurement
MH  - Pain Threshold/physiology
MH  - Surveys and Questionnaires
MH  - Temporomandibular Joint Disorders/*physiopathology/*therapy
OTO - NOTNLM
OT  - Global rating of change scale.
OT  - Minimal clinically important difference
OT  - Temporomandibular disorders
COIS- Declaration of competing interest There is no conflict of interest to me 
      declared.
EDAT- 2020/01/31 06:00
MHDA- 2021/07/20 06:00
CRDT- 2020/01/31 06:00
PHST- 2019/01/11 00:00 [received]
PHST- 2019/12/09 00:00 [revised]
PHST- 2020/01/10 00:00 [accepted]
PHST- 2020/01/31 06:00 [pubmed]
PHST- 2021/07/20 06:00 [medline]
PHST- 2020/01/31 06:00 [entrez]
AID - S2468-7812(19)30011-6 [pii]
AID - 10.1016/j.msksp.2020.102108 [doi]
PST - ppublish
SO  - Musculoskelet Sci Pract. 2020 Apr;46:102108. doi: 10.1016/j.msksp.2020.102108. 
      Epub 2020 Jan 11.