PMID- 32000284 OWN - NLM STAT- MEDLINE DCOM- 20201231 LR - 20201231 IS - 1098-9048 (Electronic) IS - 1069-3424 (Linking) VI - 41 IP - 1 DP - 2020 Feb TI - New Insights on Pulmonary Paracoccidioidomycosis. PG - 53-68 LID - 10.1055/s-0039-3400544 [doi] AB - Paracoccidioidomycosis (PCM) is one of the most relevant systemic endemic mycoses in Latin American countries, especially in South American countries, with endemic and hyperendemic areas. The real burden of PCM may be underestimated because of a lack of compulsory case notification. Recent phylogenetic data revealed that Paracoccidioides brasiliensis comprises several cryptic species including P. brasiliensis and P. lutzii. However, the genetic biodiversity of Paracoccidioides does not affect the clinical manifestations or therapeutic response to therapy. Lung involvement is a common finding, especially in patients experiencing the chronic form of the disease, and, because of its similarities with tuberculosis, clinicians must be alert to the possibility of PCM in patients with chronic respiratory manifestations and epidemiological risk factors for this fungal disease. CI - Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA. FAU - Queiroz-Telles, Fla Vio de AU - Queiroz-Telles FV AD - Department of Public Health, Hospital de Clinicas, Federal University of Parana, Parana, Brazil. FAU - Pecanha Pietrobom, Paula Massaroni AU - Pecanha Pietrobom PM AD - Division of Infectious Diseases, Department of Medicine, Escola Paulista de Medicina, Federal University of Sao Paulo, Sao Paulo, Brazil. FAU - Rosa Junior, Marcos AU - Rosa Junior M AD - Section of Radiology, Department of Medicine, Hospital Universitario Cassiano Antonio de Moraes, Federal University of Espirito Santo, Espirito Santo, Brazil. FAU - Baptista, Rodrigo de Melo AU - Baptista RM AD - Section of Radiology, Department of Medicine, Hospital Universitario Cassiano Antonio de Moraes, Federal University of Espirito Santo, Espirito Santo, Brazil. FAU - Pecanha, Paulo Mendes AU - Pecanha PM AD - Section of Infectious Diseases, Department of Medicine, Hospital Universitario Cassiano Antonio de Moraes, Federal University of Espirito Santo, Espirito Santo, Brazil. LA - eng PT - Journal Article PT - Review DEP - 20200130 PL - United States TA - Semin Respir Crit Care Med JT - Seminars in respiratory and critical care medicine JID - 9431858 RN - 0 (Anti-Infective Agents) SB - IM MH - Anti-Infective Agents/therapeutic use MH - Global Health MH - Humans MH - Lung Diseases, Fungal/*diagnosis/drug therapy/*epidemiology MH - Paracoccidioidomycosis/*diagnosis/drug therapy/*epidemiology MH - Tomography, X-Ray Computed COIS- None. EDAT- 2020/01/31 06:00 MHDA- 2021/01/01 06:00 CRDT- 2020/01/31 06:00 PHST- 2020/01/31 06:00 [entrez] PHST- 2020/01/31 06:00 [pubmed] PHST- 2021/01/01 06:00 [medline] AID - 10.1055/s-0039-3400544 [doi] PST - ppublish SO - Semin Respir Crit Care Med. 2020 Feb;41(1):53-68. doi: 10.1055/s-0039-3400544. Epub 2020 Jan 30.