PMID- 32002674
OWN - NLM
STAT- MEDLINE
DCOM- 20200811
LR  - 20221207
IS  - 1539-0829 (Electronic)
IS  - 1534-4827 (Linking)
VI  - 20
IP  - 1
DP  - 2020 Jan 30
TI  - Type 2 Diabetes and Atherosclerotic Cardiovascular Disease in South Asians: a 
      Unique Population with a Growing Challenge.
PG  - 4
LID - 10.1007/s11892-020-1291-6 [doi]
AB  - PURPOSE OF REVIEW: The purpose of this review is to summarize our current 
      knowledge of factors that influence clinical decision making and management of 
      type 2 diabetes mellitus (T2DM) and atherosclerotic cardiovascular disease 
      (ASCVD) among South Asians (SA). RECENT FINDINGS: ASCVD and T2DM in SAs have been 
      examined in recent times. Pathophysiologic and genetic factors including the role 
      of adiponectin, visceral adiposity, lower beta cell function, and psycho-social 
      factors like sedentary lifestyle, poor adherence to medications, and carbohydrate 
      dense meals play a role in early development and the high-risk presentation of 
      both ASCVD and T2DM in SA. Recently, large population-based cohort studies have 
      attempted to compare outcomes and interventions that can be translated to timely 
      detection and targeted interventions in this high-risk group. SAs in the USA are 
      more likely to be diagnosed with T2DM and ASCVD when compared to non-Hispanic 
      whites, non-Hispanic Blacks, and Hispanic populations. The development of 
      personalized ethnic risk assessment tools and better representation of SAs in 
      prospective studies are essential to increasing our understanding and management 
      of cardio-metabolic disease in SA living in the USA.
FAU - Shariff, Afreen I
AU  - Shariff AI
AD  - Division of Endocrinology, Metabolism and Nutrition, Duke University School of 
      Medicine, Durham, NC, USA. afreen.shariff@duke.edu.
AD  - DUMC, 3021, Durham, NC, 27710, USA. afreen.shariff@duke.edu.
FAU - Kumar, Nitya
AU  - Kumar N
AD  - Division of Endocrinology, Metabolism and Nutrition, Duke University School of 
      Medicine, Durham, NC, USA.
FAU - Yancy, William S Jr
AU  - Yancy WS Jr
AD  - Duke Diet and Fitness Center, Duke University Health System, Durham, NC, USA.
AD  - Durham Veterans Affairs Medical Center, Durham, NC, USA.
FAU - Corsino, Leonor
AU  - Corsino L
AD  - Division of Endocrinology, Metabolism and Nutrition, Duke University School of 
      Medicine, Durham, NC, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20200130
PL  - United States
TA  - Curr Diab Rep
JT  - Current diabetes reports
JID - 101093791
SB  - IM
MH  - Asia, Western/ethnology
MH  - *Asian
MH  - Atherosclerosis/epidemiology/*ethnology/etiology/therapy
MH  - Cardiovascular Diseases/ethnology/etiology/therapy
MH  - Clinical Decision-Making
MH  - Diabetes Mellitus, Type 2/complications/epidemiology/*ethnology/therapy
MH  - Humans
MH  - Prospective Studies
MH  - Risk Assessment
MH  - Risk Factors
MH  - United States/epidemiology
OTO - NOTNLM
OT  - Asian Indian
OT  - Atherosclerotic cardiovascular disease
OT  - Diabetes mellitus
OT  - South Asian
EDAT- 2020/02/01 06:00
MHDA- 2020/08/12 06:00
CRDT- 2020/02/01 06:00
PHST- 2020/02/01 06:00 [entrez]
PHST- 2020/02/01 06:00 [pubmed]
PHST- 2020/08/12 06:00 [medline]
AID - 10.1007/s11892-020-1291-6 [pii]
AID - 10.1007/s11892-020-1291-6 [doi]
PST - epublish
SO  - Curr Diab Rep. 2020 Jan 30;20(1):4. doi: 10.1007/s11892-020-1291-6.