PMID- 32004229
OWN - NLM
STAT- MEDLINE
DCOM- 20201019
LR  - 20210115
IS  - 1528-1159 (Electronic)
IS  - 0362-2436 (Linking)
VI  - 45
IP  - 12
DP  - 2020 Jun 15
TI  - Preoperative Mental Health Component Scoring Is Related to Patient Reported 
      Outcomes Following Lumbar Fusion.
PG  - 798-803
LID - 10.1097/BRS.0000000000003399 [doi]
AB  - STUDY DESIGN: Retrospective cohort review. OBJECTIVE: The objective of this study 
      was to identify depression using the Mental Component Score (MCS-12) of the Short 
      Form-12 (SF-12) survey and to correlate with patient outcomes. SUMMARY OF 
      BACKGROUND DATA: The impact of preexisting depressive symptoms on health-care 
      related quality of life (HRQOL) outcomes following lumbar spine fusion is not 
      well understood. METHODS: Patients undergoing lumbar fusion between one to three 
      levels at a single center, academic hospital were retrospectively identified. 
      Patients under the age of 18 years and those undergoing surgery for infection, 
      trauma, tumor, or revision, and less than 1-year follow-up were excluded. 
      Patients with depressive symptoms were identified using an existing clinical 
      diagnosis or a score of MCS-12 less than or equal to 45.6 on the preoperative 
      SF-12 survey. Absolute HRQOL scores, the recovery ratio (RR) and the percent of 
      patients achieving minimum clinically important difference (MCID) between groups 
      were compared, and a multiple linear regression analysis was performed. RESULTS: 
      A total of 391 patients were included in the total cohort, with 123 (31.5%) 
      patients reporting symptoms of depression based on MCS-12 and 268 (68.5%) without 
      these symptoms. The low MCS-12 group was found to have significantly worse 
      preoperative Oswestry disability index (ODI), visual analogue scale back pain 
      (VAS Back) and visual analogue scale leg pain (VAS Leg) scores, and postoperative 
      SF-12 physical component score (PCS-12), ODI, VAS Back, and VAS Leg pain scores 
      (P < 0.05) than the non-depressed group. Finally, multiple linear regression 
      analysis revealed preoperative depression to be a significant predictor of worse 
      outcomes after lumbar fusion. CONCLUSION: Patients with depressive symptoms, 
      identified with an MCS-12 cutoff below 45.6, were found to have significantly 
      greater disability in a variety of HRQOL domains at baseline and postoperative 
      measurement, and demonstrated less improvement in all outcome domains included in 
      the analysis compared with patients without depression. However, while the 
      improvement was less, even the low MCS-12 cohort demonstrated statistically 
      significant improvement in all HRQOL outcome measures after surgery. LEVEL OF 
      EVIDENCE: 3.
FAU - Stull, Justin D
AU  - Stull JD
AD  - Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson 
      University, Philadelphia, PA.
FAU - Divi, Srikanth N
AU  - Divi SN
FAU - Goyal, Dhruv K C
AU  - Goyal DKC
FAU - Bowles, Daniel R
AU  - Bowles DR
FAU - Reyes, Ariana A
AU  - Reyes AA
FAU - Bechay, Joseph
AU  - Bechay J
FAU - Sonnier, John Hayden
AU  - Sonnier JH
FAU - Nachwalter, Ryan N
AU  - Nachwalter RN
FAU - Zarowin, Joseph J
AU  - Zarowin JJ
FAU - Galetta, Matthew S
AU  - Galetta MS
FAU - Kaye, Ian David
AU  - Kaye ID
FAU - Woods, Barrett I
AU  - Woods BI
FAU - Kurd, Mark F
AU  - Kurd MF
FAU - Radcliff, Kris E
AU  - Radcliff KE
FAU - Rihn, Jeffrey A
AU  - Rihn JA
FAU - Anderson, David Greg
AU  - Anderson DG
FAU - Hilibrand, Alan S
AU  - Hilibrand AS
FAU - Kepler, Christopher K
AU  - Kepler CK
FAU - Vaccaro, Alexander R
AU  - Vaccaro AR
FAU - Schroeder, Gregory D
AU  - Schroeder GD
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Spine (Phila Pa 1976)
JT  - Spine
JID - 7610646
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cohort Studies
MH  - Depression
MH  - *Disability Evaluation
MH  - Disabled Persons
MH  - Female
MH  - Humans
MH  - Male
MH  - *Mental Health
MH  - Middle Aged
MH  - Pain Measurement
MH  - Patient Reported Outcome Measures
MH  - Quality of Life
MH  - Retrospective Studies
MH  - *Spinal Fusion
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
EDAT- 2020/02/01 06:00
MHDA- 2020/10/21 06:00
CRDT- 2020/02/01 06:00
PHST- 2020/02/01 06:00 [pubmed]
PHST- 2020/10/21 06:00 [medline]
PHST- 2020/02/01 06:00 [entrez]
AID - 00007632-202006150-00006 [pii]
AID - 10.1097/BRS.0000000000003399 [doi]
PST - ppublish
SO  - Spine (Phila Pa 1976). 2020 Jun 15;45(12):798-803. doi: 
      10.1097/BRS.0000000000003399.