PMID- 32007930
OWN - NLM
STAT- MEDLINE
DCOM- 20210825
LR  - 20210825
IS  - 1499-2752 (Electronic)
IS  - 0315-162X (Linking)
VI  - 47
IP  - 11
DP  - 2020 Nov 1
TI  - Expert Consensus on a Set of Outcomes to Assess the Effectiveness of Biologic 
      Treatment in Psoriatic Arthritis: The MERECES Study.
PG  - 1637-1643
LID - 10.3899/jrheum.191056 [doi]
AB  - OBJECTIVE: To reach a consensus on the instruments to be used in clinical 
      practice to evaluate the effectiveness of biological disease-modifying 
      antirheumatic drug (bDMARD) treatment in patients with psoriatic arthritis (PsA) 
      in the short to medium term (3-6 mos), and to establish the minimum health 
      outcomes for treatment continuation. METHODS: A 2-round Delphi questionnaire was 
      developed based on both the information gathered in the literature review and 4 
      discussion groups. The suitability and feasibility of the proposed sets of 
      instruments were assessed on a 7-point Likert scale. Consensus was established 
      when at least 75% of healthcare professionals (HCP) reached agreement. To define 
      a minimum health outcome to continue treatment, a combination of 4 disease 
      activity states and 3 health-related quality of life states were defined for 3 
      hypothetical patient profiles. HCP were given a dichotomous choice (yes/no) to 
      respond to whether they would continue treatment in each case. RESULTS: The 
      second round was completed by 106 HCP. Consensus was reached on the use of (1) 
      Disease Activity in Psoriatic Arthritis + Psoriatic Arthritis Impact of Disease 
      (PsAID12) or minimal disease activity + PsAID12 + C-reactive protein, in 
      peripheral PsA; and (2) Ankylosing Spondylitis Disease Activity Score + PsAID12, 
      in axial PsA. Health outcomes considered sufficient to continue treatment were 
      stricter for bDMARD-naive patients than for patients who failed several bDMARD. 
      CONCLUSION: To the best of our knowledge, this is the first multidisciplinary 
      consensus on a set of outcomes for the evaluation of bDMARD effectiveness in PsA, 
      in routine clinical practice.
FAU - Canete, Juan D
AU  - Canete JD
AUID- ORCID: 0000-0003-2606-0573
AD  - J.D. Canete, MD, PhD, Arthritis Unit, Rheumatology Department, Hospital Clinic 
      and IDIBAPS, Barcelona; jcanete@clinic.cat.
FAU - Nolla, Joan M
AU  - Nolla JM
AUID- ORCID: 0000-0002-2358-6767
AD  - J.M. Nolla, MD, PhD, Department of Rheumatology, Hospital Universitario de 
      Bellvitge IDIBELL, L'Hospitalet de Llobregat, Barcelona.
FAU - Queiro, Ruben
AU  - Queiro R
AUID- ORCID: 0000-0002-8418-7145
AD  - R. Queiro, MD, PhD, Department of Rheumatology, Hospital Universitario Central de 
      Asturias, Oviedo.
FAU - Rodriguez, Miguel J
AU  - Rodriguez MJ
AUID- ORCID: 0000-0002-6922-266X
AD  - M.J. Rodriguez, MD, Management Unit, Hospital Universitario de Cabuenes, Gijon.
FAU - Ruiz, Miguel
AU  - Ruiz M
AUID- ORCID: 0000-0002-2734-2196
AD  - M. Ruiz, PhD, Department of Social Psychology and Methodology, Facultad de 
      Psicologia, Universidad Autonoma de Madrid, Madrid.
FAU - Lizan, Luis
AU  - Lizan L
AUID- ORCID: 0000-0001-6039-2454
CN  - MERECES Working Group
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20200201
PL  - Canada
TA  - J Rheumatol
JT  - The Journal of rheumatology
JID - 7501984
RN  - 0 (Antirheumatic Agents)
RN  - 0 (Biological Products)
SB  - IM
CIN - J Rheumatol. 2020 Nov 1;47(11):1600-1602. PMID: 33139521
MH  - *Antirheumatic Agents/therapeutic use
MH  - *Arthritis, Psoriatic/drug therapy
MH  - *Biological Products/therapeutic use
MH  - Consensus
MH  - Humans
MH  - Quality of Life
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Delphi technique
OT  - antirheumatic agents
OT  - consensus
OT  - patient-reported outcome measures
OT  - psoriatic arthritis
OT  - treatment outcome
FIR - Belinchon, Isabel
IR  - Belinchon I
FIR - Chamizo, Eugenio
IR  - Chamizo E
FIR - Babio, Jesus
IR  - Babio J
FIR - Almodovar, Raquel
IR  - Almodovar R
FIR - Rio, Tamara Del
IR  - Rio TD
FIR - Poveda, Jose Luis
IR  - Poveda JL
FIR - Abad, Angel
IR  - Abad A
FIR - Mur, Carlos
IR  - Mur C
FIR - de la Cueva, Pablo
IR  - de la Cueva P
FIR - Fernandez-Carballido, Cristina
IR  - Fernandez-Carballido C
FIR - Joven, Beatriz
IR  - Joven B
FIR - Pinto, Jose A
IR  - Pinto JA
FIR - Lozano, Ana
IR  - Lozano A
FIR - Leon, Leticia
IR  - Leon L
FIR - Soto, Jose
IR  - Soto J
FIR - Galindez, Eva
IR  - Galindez E
FIR - Garcia-Vivar, Mari L
IR  - Garcia-Vivar ML
FIR - Ruibal, Ana
IR  - Ruibal A
FIR - Palmou, Natalia
IR  - Palmou N
FIR - Veroz, Raul
IR  - Veroz R
FIR - Rubio, Esteban
IR  - Rubio E
FIR - Alvarez-Vega, Jose L
IR  - Alvarez-Vega JL
FIR - Alonso, Elena
IR  - Alonso E
FIR - Marzo, Jesus
IR  - Marzo J
FIR - Garrido, Laura
IR  - Garrido L
FIR - Fabregas, Lola
IR  - Fabregas L
FIR - Garcia-Martos, Alvaro
IR  - Garcia-Martos A
FIR - Ortega, Maria C
IR  - Ortega MC
FIR - Diaz, Consuelo
IR  - Diaz C
FIR - Nieto, Juan C
IR  - Nieto JC
FIR - Torres, Carmen
IR  - Torres C
FIR - Perez-Venegas, Pepe
IR  - Perez-Venegas P
FIR - Sanz, Jesus
IR  - Sanz J
FIR - Zarco, Pedro
IR  - Zarco P
FIR - Munoz, Santiago
IR  - Munoz S
FIR - Garcia-Vicuna, Txaro
IR  - Garcia-Vicuna T
FIR - Garcia-Porrua, Carlos
IR  - Garcia-Porrua C
FIR - Meceiras, Francisco J
IR  - Meceiras FJ
FIR - Alvarez-Castro, Carolina
IR  - Alvarez-Castro C
FIR - Hernandez-Beriain, Jose A
IR  - Hernandez-Beriain JA
FIR - Gonzalez, Beatriz
IR  - Gonzalez B
FIR - Moreno, Mireia
IR  - Moreno M
FIR - Sellas, Agusti
IR  - Sellas A
FIR - Ramirez, Julio
IR  - Ramirez J
FIR - Urruticoechea, Ana
IR  - Urruticoechea A
FIR - Ponce, Andres
IR  - Ponce A
FIR - Feced, Carlos
IR  - Feced C
FIR - Martinez-Ferrer, Angels
IR  - Martinez-Ferrer A
FIR - Fernandez-Llanio, Nagore
IR  - Fernandez-Llanio N
FIR - Martinez-Cristobal, Anna
IR  - Martinez-Cristobal A
FIR - Campos, Cristina
IR  - Campos C
FIR - Conesa, Arantxa
IR  - Conesa A
FIR - Batlle, Enrique
IR  - Batlle E
FIR - Sivera, Francisca
IR  - Sivera F
FIR - Jovani, Vega
IR  - Jovani V
FIR - Judez, Enrique
IR  - Judez E
FIR - Moreno, Manuel
IR  - Moreno M
FIR - Rodriguez-Martinez, Fernando
IR  - Rodriguez-Martinez F
FIR - Laiz, Ana Maria
IR  - Laiz AM
FIR - Mateo, Lourdes
IR  - Mateo L
FIR - Pujol, Manel
IR  - Pujol M
FIR - Torre, Juan C
IR  - Torre JC
FIR - Coto, Pablo
IR  - Coto P
FIR - Notario, Jaume
IR  - Notario J
FIR - Garcia-Font, Merce
IR  - Garcia-Font M
FIR - Chaves, Antonio J
IR  - Chaves AJ
FIR - Pujol, Conrad
IR  - Pujol C
FIR - Puig, Lluis
IR  - Puig L
FIR - Dauden, Esteban
IR  - Dauden E
FIR - Sanchez-Carazo, Jose L
IR  - Sanchez-Carazo JL
FIR - Carretero, Gregorio
IR  - Carretero G
FIR - Lopez-Estebaranz, Jose L
IR  - Lopez-Estebaranz JL
FIR - Lopez-Ferrer, Anna
IR  - Lopez-Ferrer A
FIR - Pereyra-Rodriguez, Jose-Juan
IR  - Pereyra-Rodriguez JJ
FIR - Rodriguez-Fernandez, Lourdes
IR  - Rodriguez-Fernandez L
FIR - Carrascosa, Jose M
IR  - Carrascosa JM
FIR - Herranz, Pedro
IR  - Herranz P
FIR - Ruiz-Villaverde, Ricardo
IR  - Ruiz-Villaverde R
FIR - Turrion, Ana
IR  - Turrion A
FIR - Cuervo, Andrea M
IR  - Cuervo AM
FIR - Montilla, Carlos A
IR  - Montilla CA
FIR - Delgado, Concepcion
IR  - Delgado C
FIR - Palma, Deseada
IR  - Palma D
FIR - Garcia-Llorente, Jose F
IR  - Garcia-Llorente JF
FIR - Rosales, Jose L
IR  - Rosales JL
FIR - Senabre, Jose M
IR  - Senabre JM
FIR - Lerma, Juan J
IR  - Lerma JJ
FIR - Moreno, Maria J
IR  - Moreno MJ
FIR - Lopez-Lasanta, Maria
IR  - Lopez-Lasanta M
FIR - Oliva, Maria R
IR  - Oliva MR
FIR - Navio, Maria T
IR  - Navio MT
FIR - Tejon, Patricia
IR  - Tejon P
FIR - Castaneda, Santos
IR  - Castaneda S
FIR - Alonso-Castro, Sara
IR  - Alonso-Castro S
FIR - Gonzalez-Suarez, Senen
IR  - Gonzalez-Suarez S
FIR - Torrente, Vicente
IR  - Torrente V
FIR - Garcia-Portales, Rosa
IR  - Garcia-Portales R
FIR - Cancio, Jorge
IR  - Cancio J
FIR - Navarro, Victoria
IR  - Navarro V
FIR - Medina, Julio A
IR  - Medina JA
FIR - Rodriguez-Montero, Sergio
IR  - Rodriguez-Montero S
FIR - Ahijado, Pilar
IR  - Ahijado P
FIR - Hernandez, Azucena
IR  - Hernandez A
FIR - Fernandez-Espartero, Cruz
IR  - Fernandez-Espartero C
FIR - Mosquera, Jose Antonio
IR  - Mosquera JA
FIR - Reina, Delia
IR  - Reina D
FIR - Garcia, Antonio
IR  - Garcia A
FIR - Lopez, Alejandra
IR  - Lopez A
FIR - Uceda, Ana
IR  - Uceda A
FIR - Belzunegui, Joaquin
IR  - Belzunegui J
EDAT- 2020/02/03 06:00
MHDA- 2021/08/26 06:00
CRDT- 2020/02/03 06:00
PHST- 2020/01/16 00:00 [accepted]
PHST- 2020/02/03 06:00 [pubmed]
PHST- 2021/08/26 06:00 [medline]
PHST- 2020/02/03 06:00 [entrez]
AID - jrheum.191056 [pii]
AID - 10.3899/jrheum.191056 [doi]
PST - ppublish
SO  - J Rheumatol. 2020 Nov 1;47(11):1637-1643. doi: 10.3899/jrheum.191056. Epub 2020 
      Feb 1.