PMID- 32010584
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2218-6751 (Print)
IS  - 2226-4477 (Electronic)
IS  - 2218-6751 (Linking)
VI  - 8
IP  - 6
DP  - 2019 Dec
TI  - Type 2 diabetes mellitus does not increase the risk of lung cancer among 
      never-smokers: a nationwide cohort study.
PG  - 1073-1077
LID - 10.21037/tlcr.2019.11.01 [doi]
AB  - Previous studies have reported higher incidences of lung cancer among smokers 
      diagnosed with diabetes than those without. Accordingly, this study investigated 
      whether type 2 diabetes mellitus (T2DM) diagnosis alone can be associated with 
      increased lung cancer incidences among never-smokers in the Korean population. 
      Newly diagnosed never-smoking T2DM patients were identified from the nationwide 
      longitudinal cohort of health examination data of South Korea (2002-2013). Cox 
      proportional hazards regression model was employed to estimate the hazard ratios 
      (HRs) and 95% confidence interval (CI) of lung cancer in the T2DM patient and 
      abnormal fasting blood sugar (FBS) groups. T2DM (HR =0.91, 95% CI: 0.71 to 1.17) 
      and abnormal FBS level are no significant association with lung cancer incidence 
      based on the given HR. T2DM does not increase the risk of lung cancer among 
      never-smokers. A large cohort study affirms minimal impact of T2DM on lung cancer 
      development in the never-smoking Korean population.
CI  - 2019 Translational Lung Cancer Research. All rights reserved.
FAU - Park, Hyung Jun
AU  - Park HJ
AD  - Department of Family Medicine, SMG - SNU Boramae Medical Center, Seoul, Republic 
      of Korea.
AD  - Department of Family Medicine, Seoul National University Health Service Center, 
      Seoul, Republic of Korea.
AD  - Clinical Medical Sciences, College of Medicine, Seoul National University, Seoul, 
      Republic of Korea.
FAU - Joh, Hee-Kyung
AU  - Joh HK
AD  - Department of Family Medicine, Seoul National University Health Service Center, 
      Seoul, Republic of Korea.
AD  - Department of Medicine, Seoul National University College of Medicine, Seoul, 
      Republic of Korea.
AD  - Department of Family Medicine, Seoul National University Hospital, Seoul, 
      Republic of Korea.
FAU - Choi, Seulggie
AU  - Choi S
AD  - Department of Family Medicine, Seoul National University Hospital, Seoul, 
      Republic of Korea.
FAU - Park, Sang Min
AU  - Park SM
AD  - Department of Family Medicine, Seoul National University Hospital, Seoul, 
      Republic of Korea.
AD  - Department of Biomedical Science & Family Medicine, Seoul National University 
      College of Medicine, Seoul, Republic of Korea.
LA  - eng
PT  - Journal Article
PL  - China
TA  - Transl Lung Cancer Res
JT  - Translational lung cancer research
JID - 101646875
PMC - PMC6976353
OTO - NOTNLM
OT  - Lung cancer
OT  - longitudinal study
OT  - type 2 diabetes mellitus cohort analysis (T2DM cohort analysis)
COIS- Conflicts of Interest: The authors have no conflicts of interest to declare.
EDAT- 2020/02/06 06:00
MHDA- 2020/02/06 06:01
PMCR- 2019/12/01
CRDT- 2020/02/04 06:00
PHST- 2020/02/04 06:00 [entrez]
PHST- 2020/02/06 06:00 [pubmed]
PHST- 2020/02/06 06:01 [medline]
PHST- 2019/12/01 00:00 [pmc-release]
AID - tlcr-08-06-1073 [pii]
AID - 10.21037/tlcr.2019.11.01 [doi]
PST - ppublish
SO  - Transl Lung Cancer Res. 2019 Dec;8(6):1073-1077. doi: 10.21037/tlcr.2019.11.01.