PMID- 32012032 OWN - NLM STAT- MEDLINE DCOM- 20210503 LR - 20210503 IS - 2168-2208 (Electronic) IS - 2168-2194 (Linking) VI - 24 IP - 8 DP - 2020 Aug TI - Towards Domain Invariant Heart Sound Abnormality Detection Using Learnable Filterbanks. PG - 2189-2198 LID - 10.1109/JBHI.2020.2970252 [doi] AB - OBJECTIVE: Cardiac auscultation is the most practiced non-invasive and cost-effective procedure for the early diagnosis of heart diseases. While machine learning based systems can aid in automatically screening patients, the robustness of these systems is affected by numerous factors including the stethoscope/sensor, environment, and data collection protocol. This article studies the adverse effect of domain variability on heart sound abnormality detection and develops strategies to address this problem. METHODS: We propose a novel Convolutional Neural Network (CNN) layer, consisting of time-convolutional (tConv) units, that emulate Finite Impulse Response (FIR) filters. The filter coefficients can be updated via backpropagation and be stacked in the front-end of the network as a learnable filterbank. RESULTS: On publicly available multi-domain datasets, the proposed method surpasses the top-scoring systems found in the literature for heart sound abnormality detection (a binary classification task). We utilized sensitivity, specificity, F-1 score and Macc (average of sensitivity and specificity) as performance metrics. Our systems achieved relative improvements of up to 11.84% in terms of MAcc, compared to state-of-the-art methods. CONCLUSION: The results demonstrate the effectiveness of the proposed learnable filterbank CNN architecture in achieving robustness towards sensor/domain variability in PCG signals. SIGNIFICANCE: The proposed methods pave the way for deploying automated cardiac screening systems in diversified and underserved communities. FAU - Humayun, Ahmed Imtiaz AU - Humayun AI FAU - Ghaffarzadegan, Shabnam AU - Ghaffarzadegan S FAU - Ansari, Md Istiaq AU - Ansari MI FAU - Feng, Zhe AU - Feng Z FAU - Hasan, Taufiq AU - Hasan T LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20200131 PL - United States TA - IEEE J Biomed Health Inform JT - IEEE journal of biomedical and health informatics JID - 101604520 SB - IM MH - Algorithms MH - Databases, Factual MH - Heart Diseases/diagnosis MH - Heart Sounds/*physiology MH - Humans MH - *Neural Networks, Computer MH - *Phonocardiography/classification/methods MH - Sensitivity and Specificity MH - *Signal Processing, Computer-Assisted EDAT- 2020/02/06 06:00 MHDA- 2021/05/04 06:00 CRDT- 2020/02/04 06:00 PHST- 2020/02/06 06:00 [pubmed] PHST- 2021/05/04 06:00 [medline] PHST- 2020/02/04 06:00 [entrez] AID - 10.1109/JBHI.2020.2970252 [doi] PST - ppublish SO - IEEE J Biomed Health Inform. 2020 Aug;24(8):2189-2198. doi: 10.1109/JBHI.2020.2970252. Epub 2020 Jan 31.