PMID- 32013355 OWN - NLM STAT- MEDLINE DCOM- 20201118 LR - 20201118 IS - 1433-6510 (Print) IS - 1433-6510 (Linking) VI - 66 IP - 1 DP - 2020 Jan 1 TI - Variation of Hemoglobin Detection for Lipemic Blood Samples. LID - 10.7754/Clin.Lab.2019.190616 [doi] AB - BACKGROUND: Blood status is closely related to the hemoglobin test results in clinical laboratory. This paper discusses a case of which hemoglobin test results were not interfered by the "milky" blood status. METHODS: Complete Blood Count with Differential (CBC + Diff) was detected for these two specimens with a Sysmex XN-9000. RESULTS: The results of red cell indices for patient I were as follows: red blood cell count (RBC), 5.10 x 1012/L; hematocrit (HCT), 0.455 L/L; hemoglobin (HGB), 167 g/L; mean corpuscular hemoglobin concentration (MCHC), 367 g/L, and triglycerides (TG), 1.59 mmol/L. There was no "turbidity" warning message. However, there was a "turbidity" warning message for patient II and his red cell indices were RBC, 4.74 x 1012/L; HCT, 0.492 L/L; HGB, 182 g/L; MCHC, 370 g/L, and TG, 12.98 mmol/L. After the plasma exchange, there was no "turbidity" warning message for patient I and his red cell indices were RBC, 4.83 x 1012/L; HCT, 0.444 L/L; HGB, 164 g/L; MCHC, 369 g/L which were consistent with the results before the plasma exchange. For patient II, the "turbidity" warning message disappeared and his results were RBC, 3.87 x 1012/L; HCT, 0.398 L/L; HGB, 135 g/L; MCHC, 339 g/L. CONCLUSIONS: Our case provided an explanation of the normal hemoglobin detection results in the visible lipemic specimen for the first time. FAU - Fang, Weiwei AU - Fang W FAU - Zheng, Cuiling AU - Zheng C FAU - Wang, Li AU - Wang L FAU - Cui, Wei AU - Cui W LA - eng PT - Case Reports PL - Germany TA - Clin Lab JT - Clinical laboratory JID - 9705611 RN - 0 (Hemoglobins) RN - 0 (Lipids) SB - IM MH - Hematologic Tests/*methods/*standards MH - Hemoglobins/*analysis MH - Humans MH - Hyperlipidemias/*blood MH - Lipids/blood/*chemistry MH - Male MH - Middle Aged MH - Nephelometry and Turbidimetry EDAT- 2020/02/06 06:00 MHDA- 2020/11/20 06:00 CRDT- 2020/02/05 06:00 PHST- 2020/02/05 06:00 [entrez] PHST- 2020/02/06 06:00 [pubmed] PHST- 2020/11/20 06:00 [medline] AID - 10.7754/Clin.Lab.2019.190616 [doi] PST - ppublish SO - Clin Lab. 2020 Jan 1;66(1). doi: 10.7754/Clin.Lab.2019.190616.