PMID- 32013936
OWN - NLM
STAT- MEDLINE
DCOM- 20201118
LR  - 20240328
IS  - 1471-2490 (Electronic)
IS  - 1471-2490 (Linking)
VI  - 20
IP  - 1
DP  - 2020 Feb 3
TI  - Comparison of silicone versus polyurethane ureteral stents: a prospective 
      controlled study.
PG  - 10
LID - 10.1186/s12894-020-0577-y [doi]
LID - 10
AB  - BACKGROUND: Approximately 80% of patients with indwelling ureteral stents 
      experience stent related symptoms (SRS). We believe SRS can be reduced through 
      altering the composition of ureteral stents to a less firm material. Therefore, 
      we aim to compare modern silicone and polyurethane ureteral stents in terms of 
      SRS intensity and safety. METHODS: From June 2018 to October 2018, patients from 
      two distinct clinical centers were prospectively enrolled in the study and 
      stratified (non-randomly) into either control group A, patients who received 
      polyurethane stents (Rusch, Teleflex), or experimental group B, patients who 
      received silicone stents (Cook Medical). Each participant completed a survey 1 h 
      after stent insertion, in the middle of the stent dwelling period, and before 
      stent removal or ureteroscopy noting body pain and overactive bladder via the 
      visual analog scale pain (VASP) and overactive bladder (OAB) awareness tool, 
      respectively. Additionally, successfulness of stent placement, hematuria, number 
      of unplanned visits, and stent encrustation rates were assessed within each 
      group. RESULTS: A total of 50 patients participated in the study, control group A 
      consisted of 20 patients and experimental group B consisted of 30 patients. 
      Participants in group B, silicone ureteral stents, demonstrated significantly 
      lower mean values of VASP 2 weeks prior to stent removal and promptly before 
      stent removal (p = 0.023 and p = 0.014, respectively). No other comparisons 
      between the two groups were statistically significant. CONCLUSIONS: Compared to 
      polyurethane ureteral stents, silicone ureteral stents are associated with lower 
      body pain intensity assessed by VASP 2 weeks before stent removal and at the time 
      of stent removal. TRIAL REGISTRATION: Current Controlled Trials NCT04000178. 
      Retrospectively registered on June 26, 2019.
FAU - Gadzhiev, Nariman
AU  - Gadzhiev N
AD  - Department of Urology, Pavlov First Saint Petersburg State Medical University, 
      Saint Petersburg, Russia.
FAU - Gorelov, Dmitry
AU  - Gorelov D
AD  - Department of Urology, Pavlov First Saint Petersburg State Medical University, 
      Saint Petersburg, Russia.
FAU - Malkhasyan, Vigen
AU  - Malkhasyan V
AD  - Department of Urology, State University of Medicine and Dentistry, Moscow, 
      Russia.
FAU - Akopyan, Gagik
AU  - Akopyan G
AD  - Institute for Urology and Reproductive Health, Sechenov University, Moscow, 
      Russia.
FAU - Harchelava, Revaz
AU  - Harchelava R
AD  - Institute for Urology and Reproductive Health, Sechenov University, Moscow, 
      Russia.
FAU - Mazurenko, Denis
AU  - Mazurenko D
AD  - Department of Urology, Ilyinskaya Hospital, Moscow, Russia.
FAU - Kosmala, Christina
AU  - Kosmala C
AD  - Department of Urology, University of California, Irvine, 333 City Boulevard West, 
      Orange, CA, 92868, USA.
FAU - Okhunov, Zhamshid
AU  - Okhunov Z
AUID- ORCID: 0000-0001-8294-933X
AD  - Department of Urology, University of California, Irvine, 333 City Boulevard West, 
      Orange, CA, 92868, USA.
FAU - Petrov, Sergei
AU  - Petrov S
AD  - Department of Urology, Pavlov First Saint Petersburg State Medical University, 
      Saint Petersburg, Russia.
LA  - eng
SI  - ClinicalTrials.gov/NCT04000178
PT  - Comparative Study
PT  - Controlled Clinical Trial
PT  - Journal Article
PT  - Multicenter Study
DEP - 20200203
PL  - England
TA  - BMC Urol
JT  - BMC urology
JID - 100968571
RN  - 0 (Polyurethanes)
RN  - 0 (Silicones)
SB  - IM
MH  - Adult
MH  - Catheters, Indwelling/adverse effects
MH  - Device Removal/adverse effects/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Pain Measurement/*methods
MH  - *Polyurethanes
MH  - Prospective Studies
MH  - *Silicones
MH  - *Stents/adverse effects
MH  - Ureter/*surgery
MH  - Ureteroscopy/adverse effects/methods
MH  - Young Adult
PMC - PMC6998278
OTO - NOTNLM
OT  - Polyurethane
OT  - Quality of life
OT  - Silicone
OT  - Stent-related symptoms
OT  - Ureteral stent
COIS- The author(s) declare(s) that they have no competing interests. Dr. Zhamshid 
      Okhunov, as a member of the editorial board (Section Editor) of this journal, had 
      no role in the handling this manuscript.
EDAT- 2020/02/06 06:00
MHDA- 2020/11/20 06:00
PMCR- 2020/02/03
CRDT- 2020/02/05 06:00
PHST- 2019/06/10 00:00 [received]
PHST- 2020/01/20 00:00 [accepted]
PHST- 2020/02/05 06:00 [entrez]
PHST- 2020/02/06 06:00 [pubmed]
PHST- 2020/11/20 06:00 [medline]
PHST- 2020/02/03 00:00 [pmc-release]
AID - 10.1186/s12894-020-0577-y [pii]
AID - 577 [pii]
AID - 10.1186/s12894-020-0577-y [doi]
PST - epublish
SO  - BMC Urol. 2020 Feb 3;20(1):10. doi: 10.1186/s12894-020-0577-y.