PMID- 32016127
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20210111
IS  - 2328-8957 (Print)
IS  - 2328-8957 (Electronic)
IS  - 2328-8957 (Linking)
VI  - 7
IP  - 1
DP  - 2020 Jan
TI  - Cardiovascular Biomarker Profile on Antiretroviral Therapy Is Not Influenced by 
      History of an IRIS Event in People With HIV and Suppressed Viremia.
PG  - ofaa017
LID - 10.1093/ofid/ofaa017 [doi]
LID - ofaa017
AB  - Immune reconstitution inflammatory syndrome (IRIS) is characterized by release of 
      proinflammatory cytokines and tissue inflammation occurring early after 
      antiretroviral therapy (ART) initiation. The role of previous IRIS events in 
      persistent chronic inflammation in people with HIV is currently unclear. In this 
      retrospective analysis of 143 participants who maintained suppression of HIV 
      viremia, we compared biomarkers related to inflammation, coagulation, and 
      cardiovascular risk after 3 years on ART in participants with and without a 
      history of IRIS. There was no evidence of higher levels of persistent chronic 
      inflammation in people with HIV who had a history of an IRIS event. 
      ClinicalTrials.gov Identifier . NCT00286767.
CI  - Published by Oxford University Press on behalf of Infectious Diseases Society of 
      America 2020.
FAU - Gouel-Cheron, Aurelie
AU  - Gouel-Cheron A
AD  - Biostatistics Research Branch, National Institute of Allergy and Infectious 
      Diseases, National Institutes of Health, Rockville, Maryland, USA.
AD  - Departement d'Anesthesie et Reanimation Chirurgicale, Universite de Paris, Groupe 
      Hospitalier Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, 
      France.
AD  - Unit of Antibodies in Therapy and Pathology, Pasteur Institut, UMR INSERM, Paris, 
      France.
FAU - Nason, Martha
AU  - Nason M
AD  - Biostatistics Research Branch, National Institute of Allergy and Infectious 
      Diseases, National Institutes of Health, Rockville, Maryland, USA.
FAU - Rupert, Adam
AU  - Rupert A
AD  - Leidos Biomedical Research Inc., NCI Campus at Frederick, Frederick, Maryland, 
      USA.
FAU - Sheikh, Virginia
AU  - Sheikh V
AD  - Laboratory of Immunoregulation, National Institute of Allergy and Infectious 
      Diseases, National Institutes of Health, Bethesda, Maryland, USA.
FAU - Robby, Greg
AU  - Robby G
AD  - Laboratory of Immunoregulation, National Institute of Allergy and Infectious 
      Diseases, National Institutes of Health, Bethesda, Maryland, USA.
FAU - Fahle, Gary A
AU  - Fahle GA
AD  - Department of Laboratory Medicine, Clinical Center (CC), National Institutes of 
      Health, Bethesda, Maryland, USA.
FAU - Sereti, Irini
AU  - Sereti I
AUID- ORCID: 0000-0002-0076-0224
AD  - Laboratory of Immunoregulation, National Institute of Allergy and Infectious 
      Diseases, National Institutes of Health, Bethesda, Maryland, USA.
LA  - eng
SI  - ClinicalTrials.gov/NCT00286767
GR  - HHSN261200800001C/RC/CCR NIH HHS/United States
GR  - HHSN261200800001E/CA/NCI NIH HHS/United States
PT  - Journal Article
DEP - 20200111
PL  - United States
TA  - Open Forum Infect Dis
JT  - Open forum infectious diseases
JID - 101637045
PMC - PMC6991617
OTO - NOTNLM
OT  - AIDS
OT  - HIV infection
OT  - biomarkers
OT  - cytomegalovirus
OT  - immune reconstitution inflammatory syndrome (IRIS)
OT  - inflammation
EDAT- 2020/02/06 06:00
MHDA- 2020/02/06 06:01
PMCR- 2021/01/11
CRDT- 2020/02/05 06:00
PHST- 2019/10/28 00:00 [received]
PHST- 2020/01/09 00:00 [accepted]
PHST- 2020/02/05 06:00 [entrez]
PHST- 2020/02/06 06:00 [pubmed]
PHST- 2020/02/06 06:01 [medline]
PHST- 2021/01/11 00:00 [pmc-release]
AID - ofaa017 [pii]
AID - 10.1093/ofid/ofaa017 [doi]
PST - epublish
SO  - Open Forum Infect Dis. 2020 Jan 11;7(1):ofaa017. doi: 10.1093/ofid/ofaa017. 
      eCollection 2020 Jan.