PMID- 32017116
OWN - NLM
STAT- MEDLINE
DCOM- 20210218
LR  - 20210218
IS  - 1943-3670 (Electronic)
IS  - 0022-3492 (Linking)
VI  - 91
IP  - 9
DP  - 2020 Sep
TI  - Clinicoradiographic markers of peri-implantitis in cigarette-smokers and 
      never-smokers with type 2 diabetes mellitus at 7-years follow-up.
PG  - 1132-1138
LID - 10.1002/JPER.19-0501 [doi]
AB  - BACKGROUND: It is hypothesized that in the long-term, (a) peri-implant 
      inflammatory variables (plaque index [PI], bleeding on probing [BOP], probing 
      depth (PD) and crestal bone loss [CBL]) are worse in cigarette-smokers (CS) and 
      patients with type-2 diabetes mellitus (T2DM) than never-smokers (NS) without 
      T2DM. The aim of the present 7-year follow-up clinical observational study was to 
      assess the survival of dental implant in CS and NS with T2DM. METHODS: Study 
      participants were divided into four groups based on glycemic status and 
      self-reported cigarette-smoking habit: a) CS with T2DM; b) CS without T2DM; c) NS 
      with T2DM; and d) NS without T2DM. Demographic information was collected using a 
      questionnaire and hemoglobin A1c (HbA1c) levels were measured. Peri-implant PI, 
      BOP, PD, and CBL were measured. Sample-size was estimated was statistical 
      analysis was done using analysis of variance. P <0.01 was considered significant. 
      RESULTS: In total, 101 male patients were included. There was no significant 
      contrast in age among the groups. Every partaker in the study groups had one 
      dental implant placed in posterior maxilla or mandible. The mean HbA1c levels 
      were significantly higher among CS (P <0.01) and NS (P <0.01) with T2DM than 
      individuals without T2DM. Peri-implant PI (P <0.01), PD (P <0.01), and CBL 
      (P <0.01) were significantly higher among CS and NS with T2DM and CS without T2DM 
      than NS without T2DM. Peri-implant BOP was significantly higher among CS and NS 
      with T2DM than CS and NS without T2DM (P <0.01). CONCLUSIONS: Peri-implant 
      inflammatory variables were worse among CS and NS with T2DM than NS without T2DM. 
      A state of chronic hyperglycemia seems to be a stronger mediator of inflammation 
      than cigarette smoking in patients with T2DM.
CI  - (c) 2020 American Academy of Periodontology.
FAU - Alqahtani, Fawaz
AU  - Alqahtani F
AD  - Department of Prosthodontics, College of Dentistry, Prince Sattam Bin Abdulaziz 
      University, Al-Kharj, Saudi Arabia.
FAU - Alqhtani, Nasser
AU  - Alqhtani N
AD  - Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, College of 
      Dentistry, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.
FAU - Alkhtani, Fahad
AU  - Alkhtani F
AD  - Department of Prosthodontics, College of Dentistry, Prince Sattam Bin Abdulaziz 
      University, Al-Kharj, Saudi Arabia.
FAU - Devang Divakar, Darshan
AU  - Devang Divakar D
AD  - Dental Biomaterials Research Chair, Dental Health Department, College of Applied 
      Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
FAU - Al-Kheraif, Abdulaziz A
AU  - Al-Kheraif AA
AD  - Dental Biomaterials Research Chair, Dental Health Department, College of Applied 
      Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
FAU - Javed, Fawad
AU  - Javed F
AD  - Department of Periodontology, Laboratory for Periodontal-, Implant-, Phototherapy 
      (LA-PIP), School of Dental Medicine, Stony Brook University, Stony Brook, NY, 
      USA.
AD  - Division of Orthodontics and Dentofacial Orthopedics, Eastman Institute for Oral 
      Health, University of Rochester, Rochester, NY, USA.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20200305
PL  - United States
TA  - J Periodontol
JT  - Journal of periodontology
JID - 8000345
RN  - 0 (Dental Implants)
SB  - IM
MH  - *Dental Implants
MH  - Dental Plaque Index
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - *Peri-Implantitis/diagnostic imaging/etiology
MH  - Smokers
MH  - *Tobacco Products
OTO - NOTNLM
OT  - Type 2; hyperglycemia; periodontal index
OT  - alveolar bone loss; dental implants; diabetes mellitus
EDAT- 2020/02/06 06:00
MHDA- 2021/02/20 06:00
CRDT- 2020/02/05 06:00
PHST- 2019/09/05 00:00 [received]
PHST- 2020/01/04 00:00 [revised]
PHST- 2020/01/14 00:00 [accepted]
PHST- 2020/02/06 06:00 [pubmed]
PHST- 2021/02/20 06:00 [medline]
PHST- 2020/02/05 06:00 [entrez]
AID - 10.1002/JPER.19-0501 [doi]
PST - ppublish
SO  - J Periodontol. 2020 Sep;91(9):1132-1138. doi: 10.1002/JPER.19-0501. Epub 2020 Mar 
      5.