PMID- 32019777
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2398-3795 (Electronic)
IS  - 2398-3795 (Linking)
VI  - 4
IP  - 1
DP  - 2020
TI  - Potentially inappropriate medications in older patients based on Beers criteria: 
      a cross-sectional study of a family medicine practice in Saudi Arabia.
LID - bjgpopen20X101009 [pii]
LID - 10.3399/bjgpopen20X101009 [doi]
AB  - BACKGROUND: The use of potentially inappropriate medications (PIMs) is an 
      important issue in older patients who are at risk of adverse drug events. AIM: To 
      determine the prevalence of PIM use, according to Beers criteria, among an older 
      population (aged >/=65 years) in a large family medicine setting, and to identify 
      the associated risks. DESIGN & SETTING: A prospective cross-sectional study of 
      patients aged >/=65 years was conducted from June 2017 to June 2018 at the Family 
      and Community Medicine (FCM) clinics of King Saud Medical City (KSMC) in Riyadh, 
      Saudi Arabia. METHOD: This cross-sectional study included patients aged >/=65 years 
      who were seen at new appointments or followed-up at the FCM clinics of KSMC in 
      Riyadh, Saudi Arabia. Data were collected by extensive face-to-face interviews 
      and from the patients' medical records. RESULTS: A total of 270 older patients 
      aged 72.41 +/-6.23 years (mean +/-standard deviation [SD]) were included in the 
      present study. The prevalence of PIMs was 60.7% (n = 164). Multivariate analyses 
      identified three independent variables associated with PIMs: incremental age per 
      5 years (odds ratio [OR] 1.47, 95% confidence intervals [CI] = 1.15 to 1.88; P = 
      0.002), female sex (OR 1.95, 95% CI = 1.10 to 3.42; P = 0.021), and polypharmacy 
      (OR 8.21, 95% CI = 4.58 to 14.7; P<0.001). The most common PIMs used were 39.4% 
      related to proton pump inhibitors (PPI), 25.2% to diuretics (other than 
      spironolactone), 10.6% to non-steroidal anti-inflammatory drugs (NSAIDs), and 
      8.7% to aspirin use. CONCLUSION: This study showed high prevalence of PIMs. 
      Increasing age, female sex, and polypharmacy were found to be significant risk 
      factors for PIM use. The frequency of morbidities was not significantly different 
      among patients with PIMs compared to those without PIMs, except for hypertension 
      and osteoarthritis, which were more common in the PIMs group. The present study 
      reinforces the importance of comprehensive medication management and reviews.
CI  - Copyright (c) 2020, The Authors.
FAU - Alturki, Atheer
AU  - Alturki A
AD  - Family Medicine Specialist, King Saud Medical City, Central Health Cluster One, 
      Riyadh, Kingdom of Saudi Arabia.
FAU - Alaama, Tareef
AU  - Alaama T
AD  - Deputy Minister for Therapeutic Affairs, Ministry of Health, Deputyship of 
      Therapeutic Affairs, Riyadh, Kingdom of Saudi Arabia.
AD  - Assistant Professor and Consultant of Internal Medicine & Geriatric Medicine, 
      King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
FAU - Alomran, Yousef
AU  - Alomran Y
AD  - Consultant of Family Medicine and Associate Executive Director for Primary Care 
      and Community Health, King Saud Medical City, Central Health Cluster One, Riyadh, 
      Kingdom of Saudi Arabia.
FAU - Al-Jedai, Ahmed
AU  - Al-Jedai A
AD  - Assistant Deputy Minister for Medical Support Services, Ministry of Health, 
      Deputyship of Therapeutic Affairs, Riyadh, Kingdom of Saudi Arabia.
AD  - Professor and Consultant Clinical Pharmacist, Solid Organ Transplant, College of 
      Medicine and Pharmacy, Alfaisal University, Riyadh, Kingdom of Saudi Arabia.
FAU - Almudaiheem, Hajer
AU  - Almudaiheem H
AD  - Drug Policy Department Manager, Ministry of Health, Deputyship of Therapeutic 
      Affairs, Riyadh, Kingdom of Saudi Arabia.
FAU - Watfa, Ghassan
AU  - Watfa G
AUID- ORCID: 0000-0002-1559-6930
AD  - Consultant of Geriatric Medicine and Director of Home Health Care Administration, 
      King Saud Medical City, Central Health Cluster One, Riyadh, Kingdom of Saudi 
      Arabia g.watfa@ksmc.med.sa.
LA  - eng
PT  - Journal Article
DEP - 20200501
PL  - England
TA  - BJGP Open
JT  - BJGP open
JID - 101713531
PMC - PMC7330182
OTO - NOTNLM
OT  - Beers criteria
OT  - Saudi Arabia
OT  - aged
OT  - family medicine
OT  - geriatrics
OT  - potentially inappropriate medications
EDAT- 2020/02/06 06:00
MHDA- 2020/02/06 06:01
PMCR- 2020/02/05
CRDT- 2020/02/06 06:00
PHST- 2019/07/31 00:00 [received]
PHST- 2019/10/03 00:00 [accepted]
PHST- 2020/02/06 06:00 [pubmed]
PHST- 2020/02/06 06:01 [medline]
PHST- 2020/02/06 06:00 [entrez]
PHST- 2020/02/05 00:00 [pmc-release]
AID - bjgpopen20X101009 [pii]
AID - 01009 [pii]
AID - 10.3399/bjgpopen20X101009 [doi]
PST - epublish
SO  - BJGP Open. 2020 May 1;4(1):bjgpopen20X101009. doi: 10.3399/bjgpopen20X101009. 
      Print 2020.