PMID- 32022581
OWN - NLM
STAT- MEDLINE
DCOM- 20210129
LR  - 20210129
IS  - 1759-9873 (Electronic)
IS  - 0964-5284 (Linking)
VI  - 38
IP  - 5
DP  - 2020 Oct
TI  - Electroacupuncture versus manual acupuncture for knee osteoarthritis: a 
      randomized controlled pilot trial.
PG  - 291-300
LID - 10.1177/0964528419900781 [doi]
AB  - OBJECTIVE: We aimed to explore the feasibility of evaluating the comparative 
      effectiveness and safety of electroacupuncture (EA) relative to manual 
      acupuncture (MA) for the treatment of knee osteoarthritis (KOA). METHODS: A 
      multicenter randomized controlled clinical trial was conducted in Beijing from 
      September 2017 to January 2018. A total of 60 participants with KOA were randomly 
      allocated to either EA (n = 30) or MA (n = 30) groups. Participants in the EA 
      group were treated with EA at six to seven local traditional acupuncture points 
      or ah shi points, and two to three distal points. Participants in the MA group 
      had the same schedule as the EA group except that the electrical apparatus 
      featured a working power indicator without actual current output, constituting a 
      sham EA procedure, in order to blind participants. Both groups received 24 
      sessions over 8 weeks. The primary outcome was response rate, defined as a change 
      of ⩾50% from baseline in the total scores of the Western Ontario and McMaster 
      Universities Osteoarthritis Index (WOMAC) after 8 weeks. Secondary outcomes 
      included pain, stiffness, function, quality of life, and acupuncture-related 
      adverse events (AEs) at 4 and 8 weeks. RESULTS: Of 60 participants randomized, 53 
      (88%) completed the study. Response rates were 43% for the EA group and 30% for 
      the MA group by the intention-to-treat analysis. Although significant differences 
      were observed in WOMAC pain, stiffness, and function scores within both groups, 
      between-group differences at 8 weeks did not reach statistical significance (odds 
      ratio = 1.75 (95% confidence interval = 0.593-5.162)). Rates of AEs were low and 
      similarly distributed between groups. CONCLUSION: Both EA and MA interventions in 
      KOA were feasible and appeared safe. Whether or not EA may have a stronger impact 
      on pain and function requires further evaluation through larger, adequately 
      powered, randomized controlled trials. TRIAL REGISTRATION NUMBER: NCT03274713.
FAU - Wang, Tian-Qi
AU  - Wang TQ
AD  - Acupuncture Research Center, School of Acupuncture, Moxibustion and Tuina, 
      Beijing University of Chinese Medicine, Beijing, China.
FAU - Li, Yong-Ting
AU  - Li YT
AD  - Acupuncture Research Center, School of Acupuncture, Moxibustion and Tuina, 
      Beijing University of Chinese Medicine, Beijing, China.
FAU - Wang, Li-Qiong
AU  - Wang LQ
AD  - Acupuncture Research Center, School of Acupuncture, Moxibustion and Tuina, 
      Beijing University of Chinese Medicine, Beijing, China.
FAU - Shi, Guang-Xia
AU  - Shi GX
AD  - Acupuncture Research Center, School of Acupuncture, Moxibustion and Tuina, 
      Beijing University of Chinese Medicine, Beijing, China.
FAU - Tu, Jian-Feng
AU  - Tu JF
AUID- ORCID: 0000-0003-2887-3383
AD  - Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional 
      Chinese Medicine, Capital Medical University, Beijing, China.
FAU - Yang, Jing-Wen
AU  - Yang JW
AD  - Acupuncture Research Center, School of Acupuncture, Moxibustion and Tuina, 
      Beijing University of Chinese Medicine, Beijing, China.
FAU - Hou, Ya-Quan
AU  - Hou YQ
AD  - Acupuncture Research Center, School of Acupuncture, Moxibustion and Tuina, 
      Beijing University of Chinese Medicine, Beijing, China.
FAU - Lin, Lu-Lu
AU  - Lin LL
AD  - Acupuncture Research Center, School of Acupuncture, Moxibustion and Tuina, 
      Beijing University of Chinese Medicine, Beijing, China.
FAU - Sun, Ning
AU  - Sun N
AD  - Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, 
      Chengdu, China.
FAU - Zhao, Jing-Jie
AU  - Zhao JJ
AD  - Department of Acupuncture and Moxibustion, Beijing Friendship Hospital, Capital 
      Medical University, Beijing, China.
FAU - Hou, Hai-Kun
AU  - Hou HK
AD  - Department of Acupuncture and Moxibustion, Beijing Jishuitan Hospital, The Fourth 
      Medical College of Peking University, Beijing, China.
FAU - Liu, Cun-Zhi
AU  - Liu CZ
AUID- ORCID: 0000-0001-8031-5667
AD  - Acupuncture Research Center, School of Acupuncture, Moxibustion and Tuina, 
      Beijing University of Chinese Medicine, Beijing, China.
LA  - eng
SI  - ClinicalTrials.gov/NCT03274713
PT  - Comparative Study
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20200205
PL  - England
TA  - Acupunct Med
JT  - Acupuncture in medicine : journal of the British Medical Acupuncture Society
JID - 9304117
SB  - IM
MH  - Acupuncture Points
MH  - *Acupuncture Therapy
MH  - Aged
MH  - *Electroacupuncture
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Osteoarthritis, Knee/*therapy
MH  - Pilot Projects
MH  - Treatment Outcome
OTO - NOTNLM
OT  - electroacupuncture
OT  - knee osteoarthritis
OT  - manual acupuncture
OT  - randomized controlled trial
EDAT- 2020/02/06 06:00
MHDA- 2021/01/30 06:00
CRDT- 2020/02/06 06:00
PHST- 2020/02/06 06:00 [pubmed]
PHST- 2021/01/30 06:00 [medline]
PHST- 2020/02/06 06:00 [entrez]
AID - 10.1177/0964528419900781 [doi]
PST - ppublish
SO  - Acupunct Med. 2020 Oct;38(5):291-300. doi: 10.1177/0964528419900781. Epub 2020 
      Feb 5.