PMID- 32024026
OWN - NLM
STAT- MEDLINE
DCOM- 20201118
LR  - 20201118
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 12
IP  - 2
DP  - 2020 Jan 31
TI  - The Role of Dietary Carbohydrates in Gestational Diabetes.
LID - 10.3390/nu12020385 [doi]
LID - 385
AB  - Gestational diabetes (GDM) is hyperglycemia that is recognized for the first time 
      during pregnancy. GDM is associated with a wide range of short- and long-term 
      adverse health consequences for both mother and offspring. It is a complex 
      disease with a multifactorial etiology, with disturbances in glucose, lipid, 
      inflammation and gut microbiota. Consequently, its management is complex, 
      requiring patients to self-manage their diet, lifestyle and self-care behaviors 
      in combination with use of insulin. In addition to nutritional recommendations 
      for all pregnant women, special attention to dietary carbohydrate (CHO) amount 
      and type on glucose levels is especially important in GDM. Dietary CHO are 
      diverse, ranging from simple sugars to longer-chain oligo- and poly- saccharides 
      which have diverse effects on blood glucose, microbial fermentation and bowel 
      function. Studies have established that dietary CHO amount and type can impact 
      maternal glucose and nutritional recommendations advise women with GDM to limit 
      total intake or choose complex and low glycemic CHO. However, robust maternal and 
      infant benefits are not consistently shown. Novel approaches which help women 
      with GDM adhere to dietary recommendations such as diabetes-specific meal 
      replacements (which provide a defined and complete nutritional composition with 
      slowly-digested CHO) and continuous glucose monitors (which provide unlimited 
      monitoring of maternal glycemic fluctuations) have shown benefits on both 
      maternal and neonatal outcomes. Continued research is needed to understand and 
      develop tools to facilitate patient adherence to treatment goals, individualize 
      interventions and improve outcomes.
FAU - Mustad, Vikkie A
AU  - Mustad VA
AD  - R&D Department, Abbott Nutrition, Columbus, OH, 43219, USA.
FAU - Huynh, Dieu T T
AU  - Huynh DTT
AD  - R&D Department, Abbott Nutrition, Singapore 138668, Singapore.
FAU - Lopez-Pedrosa, Jose M
AU  - Lopez-Pedrosa JM
AD  - R&D Department, Abbott Nutrition, 18004 Granada, Spain.
FAU - Campoy, Cristina
AU  - Campoy C
AD  - Department of Paediatrics, University of Granada, 18071 Granada, Spain.
AD  - EURISTIKOS Excellence Centre for Paediatric Research. University of Granada, 
      18071 Granada, Spain.
FAU - Rueda, Ricardo
AU  - Rueda R
AD  - R&D Department, Abbott Nutrition, 18004 Granada, Spain.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20200131
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
SB  - IM
MH  - Blood Glucose/drug effects
MH  - Diabetes, Gestational/blood/*diet therapy/etiology
MH  - Diet, Diabetic/*methods
MH  - Dietary Carbohydrates/*analysis
MH  - Female
MH  - Glycemic Index/drug effects
MH  - Humans
MH  - Maternal Nutritional Physiological Phenomena
MH  - Pregnancy
MH  - Prenatal Care/*methods
PMC - PMC7071246
OTO - NOTNLM
OT  - continuous glucose monitoring
OT  - diabetes-specific formula
OT  - dietary carbohydrates
OT  - gestational diabetes mellitus
OT  - pregnancy
COIS- V.A.M., D.T.T.H., J.M.L.-P., R.R. are employees and stockholders of Abbott 
      Nutrition. C.C. has no conflict of interest.
EDAT- 2020/02/07 06:00
MHDA- 2020/11/20 06:00
PMCR- 2020/02/01
CRDT- 2020/02/07 06:00
PHST- 2019/12/18 00:00 [received]
PHST- 2020/01/17 00:00 [revised]
PHST- 2020/01/27 00:00 [accepted]
PHST- 2020/02/07 06:00 [entrez]
PHST- 2020/02/07 06:00 [pubmed]
PHST- 2020/11/20 06:00 [medline]
PHST- 2020/02/01 00:00 [pmc-release]
AID - nu12020385 [pii]
AID - nutrients-12-00385 [pii]
AID - 10.3390/nu12020385 [doi]
PST - epublish
SO  - Nutrients. 2020 Jan 31;12(2):385. doi: 10.3390/nu12020385.