PMID- 32026744
OWN - NLM
STAT- MEDLINE
DCOM- 20210929
LR  - 20210929
IS  - 1552-4523 (Electronic)
IS  - 0733-4648 (Linking)
VI  - 40
IP  - 6
DP  - 2021 Jun
TI  - The Association Between Antipsychotic Drug Use and Rehabilitation Outcome in 
      Post-Acute Hip Fractured Patients: A Retrospective Cohort Study.
PG  - 661-669
LID - 10.1177/0733464820904564 [doi]
AB  - Antipsychotic (AP) use may lead to numerous side effects which may affect 
      rehabilitation outcomes. A retrospective cohort study was carried out on 448 hip 
      fractured patients admitted to a post-acute geriatric rehabilitation center. 
      Functional improvement was measured by the Functional Independence Measure (FIM), 
      motor FIM (mFIM), and mFIM effectiveness. A multiple linear regression model and 
      regression analysis was used to evaluate the level of association between AP use 
      and achievement of favorable functional gain. AP users exhibited lower functional 
      ability on admission and at discharge, achieved a significantly lower functional 
      gain and required longer rehabilitation time compared with nonusers. AP use by 
      post-acute hip fractured patients negatively affects their chances of achieving 
      favorable rehabilitation outcome after adjustment for confounders.
FAU - Hershkovitz, Avital
AU  - Hershkovitz A
AUID- ORCID: 0000-0002-3473-6695
AD  - "Beit Rivka" Geriatric Rehabilitation Center, Petah Tikva, Israel.
AD  - Tel Aviv University, Israel.
FAU - Nissan, Ran
AU  - Nissan R
AD  - "Beit Rivka" Geriatric Rehabilitation Center, Petah Tikva, Israel.
LA  - eng
PT  - Journal Article
DEP - 20200206
PL  - United States
TA  - J Appl Gerontol
JT  - Journal of applied gerontology : the official journal of the Southern 
      Gerontological Society
JID - 8606502
RN  - 0 (Antipsychotic Agents)
SB  - IM
MH  - Activities of Daily Living
MH  - Aged
MH  - *Antipsychotic Agents/therapeutic use
MH  - *Hip Fractures
MH  - Humans
MH  - Recovery of Function
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - antipsychotics
OT  - hip fracture
OT  - older adults
OT  - rehabilitation outcomes
EDAT- 2020/02/07 06:00
MHDA- 2021/09/30 06:00
CRDT- 2020/02/07 06:00
PHST- 2020/02/07 06:00 [pubmed]
PHST- 2021/09/30 06:00 [medline]
PHST- 2020/02/07 06:00 [entrez]
AID - 10.1177/0733464820904564 [doi]
PST - ppublish
SO  - J Appl Gerontol. 2021 Jun;40(6):661-669. doi: 10.1177/0733464820904564. Epub 2020 
      Feb 6.