PMID- 32037646
OWN - NLM
STAT- In-Process
LR  - 20200430
IS  - 1600-0838 (Electronic)
IS  - 0905-7188 (Linking)
VI  - 30
IP  - 5
DP  - 2020 May
TI  - Estimated cardiorespiratory fitness in childhood and cardiometabolic health in
      adulthood: 1970 British Cohort Study.
PG  - 932-938
LID - 10.1111/sms.13637 [doi]
AB  - BACKGROUND: Associations of cardiorespiratory fitness in childhood and adulthood 
      with adult cardiometabolic risk factors are poorly understood, not least because 
      of the paucity of studies. OBJECTIVES: We investigated associations between
      nonexercise testing cardiorespiratory fitness (NETCRF) in childhood/adulthood and
      cardiometabolic risk factors in adulthood. METHODS: Based on an established
      algorithm comprising gender, age, body mass index, resting heart rate, and
      self-reported physical activity at age 10, we computed NETCRF. Risk factors were 
      assessed at age 46 in 5009 participants when NETCRF was again calculated. Linear 
      regression was used to summarize associations between NETCRF in childhood and
      risk factors in adulthood and, additionally, the relationship between NETCRF in
      adulthood and risk factors in adulthood after adjusting for childhood NETCRF.
      RESULTS: Inconsistent associations were observed between childhood NETCRF and
      adult risk factors. NETCRF in adulthood was associated with blood pressure [-5.8 
      (-6.7, -4.9)], glycated hemoglobin [-3.41 (-4.06, -2.76)], total cholesterol
      [-0.16 (-0.24, -0.08)], HDL cholesterol [0.19 (0.16, 0.22)], triglycerides [-0.68
      (-0.85, -0.50)], and C-reactive protein [-0.29 (-0.35, -0.22)] in adult males.
      Similar associations were observed in adult females. Compared to those with low
      estimated fitness in both childhood and adulthood, participants with low fitness 
      in childhood and high fitness in adulthood had a lower risk of two or more
      cardiometabolic risk factors (odds ratio: 0.25; 95% confidence interval: 0.19,
      0.31). CONCLUSION: Associations between estimated fitness and risk factors are
      stronger in adulthood than from childhood to adulthood. Adults with previously
      sedentary childhoods may still gain benefits from improving their fitness.
CI  - (c) 2020 The Authors. Scandinavian Journal of Medicine & Science In Sports
      published by John Wiley & Sons Ltd.
FAU - Hamer, Mark
AU  - Hamer M
AUID- ORCID: https://orcid.org/0000-0002-8726-7992
AD  - Division of Surgery & Interventional Science, Faculty of Medical Sciences,
      Institute Sport Exercise Health, University College London, London, UK.
FAU - O'Donovan, Gary
AU  - O'Donovan G
AD  - Facultad de Medicina, Universidad de los Andes, Bogota, Colombia.
FAU - Batty, G David
AU  - Batty GD
AD  - Department of Epidemiology & Public Health, University College London, London,
      UK.
AD  - School of Biological & Population Health Sciences, Oregon State University,
      Corvallis, OR, USA.
FAU - Stamatakis, Emmanuel
AU  - Stamatakis E
AD  - Charles Perkins Centre, The University of Sydney, Sydney, NSW, Australia.
AD  - School of Public Health, Prevention Research Collaboration, The University of
      Sydney, Sydney, NSW, Australia.
LA  - eng
GR  - SP/15/6/31397/BHF_/British Heart Foundation/United Kingdom
GR  - RES-579-47-0001/Economic Social Research Council and Medical Research Council
GR  - SP/15/6/31397/BHF_/British Heart Foundation/United Kingdom
PT  - Journal Article
DEP - 20200226
PL  - Denmark
TA  - Scand J Med Sci Sports
JT  - Scandinavian journal of medicine & science in sports
JID - 9111504
SB  - IM
PMC - PMC7187251
OTO - NOTNLM
OT  - cohort
OT  - fitness
OT  - metabolic
OT  - population
EDAT- 2020/02/11 06:00
MHDA- 2020/02/11 06:00
CRDT- 2020/02/11 06:00
PHST- 2019/10/15 00:00 [received]
PHST- 2020/01/22 00:00 [revised]
PHST- 2020/02/04 00:00 [accepted]
PHST- 2020/02/11 06:00 [pubmed]
PHST- 2020/02/11 06:00 [medline]
PHST- 2020/02/11 06:00 [entrez]
AID - 10.1111/sms.13637 [doi]
PST - ppublish
SO  - Scand J Med Sci Sports. 2020 May;30(5):932-938. doi: 10.1111/sms.13637. Epub 2020
      Feb 26.