PMID- 32038840
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 1976-8257 (Print)
IS  - 2234-2753 (Electronic)
IS  - 1976-8257 (Linking)
VI  - 25
IP  - 4
DP  - 2009 Dec
TI  - Effects of Concrete and Wood Building Environments on Pregnant Dams and 
      Embryo-Fetal Development in Rats.
PG  - 209-216
LID - 10.5487/TR.2009.25.4.209 [doi]
AB  - We have recently reported that the continuous exposure of rats to a concrete 
      building environment under cool temperatures had adverse effects on general 
      health parameters and embryo-fetal development. This study examined to compare 
      the potential effects of concrete and wood building environments on pregnant dams 
      and embryo-fetal development in rats. Groups of 10 mated females were exposed to 
      polycarbonate (control), concrete, or wood cages from gestational days (GD) 0 to 
      20 under cool temperatures (11.9 approximately 12.3 degrees C). All the females underwent a caesarean 
      section on GD 20, and their fetuses were examined for any morphological 
      abnormalities. The temperatures in the cages were similar in all groups but the 
      relative humidity in the concrete and wood groups were higher than in the control 
      group. The concentration of volatile organic compounds in the wood group was 
      higher than in the control group. In the concrete group, maternal effects 
      manifested as an increase in the incidence of clinical signs, a lower body 
      weight, and a decrease in the thymus and ovary weights. Developmental effects 
      included increased post-implantation loss and decreased litter size. Infrared 
      thermal analysis showed that the skin temperature of the rats in the concrete 
      group was lower than that in the control group. In contrast, there were no 
      exposure-related adverse effects on the maternal and developmental parameters in 
      the wood group. Overall, the exposure of pregnant rats to a concrete building 
      environment under cool temperatures has adverse effects on the clinical signs, 
      body weight, skin temperature, organ weight, and embryo-fetal development. On the 
      other hand, exposure to a wood building environment does not have any adverse 
      effects in rats.
CI  - (c) Korean Society of Toxicology 2009.
FAU - Shin, In-Sik
AU  - Shin IS
AD  - 17Animal Medical Center, College of Veterinary Medicine, Chonnam National 
      University, Gwangju, 500-757 Korea. GRID: grid.14005.30. ISNI: 0000 0001 0356 
      9399
FAU - Kim, Sung-Hwan
AU  - Kim SH
AD  - 17Animal Medical Center, College of Veterinary Medicine, Chonnam National 
      University, Gwangju, 500-757 Korea. GRID: grid.14005.30. ISNI: 0000 0001 0356 
      9399
FAU - Lim, Jeong-Hyeon
AU  - Lim JH
AD  - 17Animal Medical Center, College of Veterinary Medicine, Chonnam National 
      University, Gwangju, 500-757 Korea. GRID: grid.14005.30. ISNI: 0000 0001 0356 
      9399
FAU - Lee, Jong-Chan
AU  - Lee JC
AD  - 17Animal Medical Center, College of Veterinary Medicine, Chonnam National 
      University, Gwangju, 500-757 Korea. GRID: grid.14005.30. ISNI: 0000 0001 0356 
      9399
FAU - Park, Na-Hyeong
AU  - Park NH
AD  - 17Animal Medical Center, College of Veterinary Medicine, Chonnam National 
      University, Gwangju, 500-757 Korea. GRID: grid.14005.30. ISNI: 0000 0001 0356 
      9399
FAU - Shin, Dong-Ho
AU  - Shin DH
AD  - 17Animal Medical Center, College of Veterinary Medicine, Chonnam National 
      University, Gwangju, 500-757 Korea. GRID: grid.14005.30. ISNI: 0000 0001 0356 
      9399
FAU - Moon, Changjong
AU  - Moon C
AD  - 17Animal Medical Center, College of Veterinary Medicine, Chonnam National 
      University, Gwangju, 500-757 Korea. GRID: grid.14005.30. ISNI: 0000 0001 0356 
      9399
FAU - Kim, Sung-Ho
AU  - Kim SH
AD  - 17Animal Medical Center, College of Veterinary Medicine, Chonnam National 
      University, Gwangju, 500-757 Korea. GRID: grid.14005.30. ISNI: 0000 0001 0356 
      9399
FAU - Kim, Jong-Choon
AU  - Kim JC
AD  - 17Animal Medical Center, College of Veterinary Medicine, Chonnam National 
      University, Gwangju, 500-757 Korea. GRID: grid.14005.30. ISNI: 0000 0001 0356 
      9399
LA  - eng
PT  - Journal Article
DEP - 20091230
PL  - Singapore
TA  - Toxicol Res
JT  - Toxicological research
JID - 101483324
PMC - PMC7006279
OTO - NOTNLM
OT  - Building materials
OT  - Concrete
OT  - Embryo-fetal development
OT  - Pregnancy
OT  - Rats
OT  - Wood
EDAT- 2009/12/01 00:00
MHDA- 2009/12/01 00:01
PMCR- 2010/12/01
CRDT- 2020/02/11 06:00
PHST- 2009/10/08 00:00 [received]
PHST- 2009/10/22 00:00 [revised]
PHST- 2009/10/23 00:00 [accepted]
PHST- 2020/02/11 06:00 [entrez]
PHST- 2009/12/01 00:00 [pubmed]
PHST- 2009/12/01 00:01 [medline]
PHST- 2010/12/01 00:00 [pmc-release]
AID - 2504209 [pii]
AID - 10.5487/TR.2009.25.4.209 [doi]
PST - ppublish
SO  - Toxicol Res. 2009 Dec;25(4):209-216. doi: 10.5487/TR.2009.25.4.209. Epub 2009 Dec 
      30.