PMID- 32039837
OWN - NLM
STAT- MEDLINE
DCOM- 20201109
LR  - 20201109
IS  - 1875-8622 (Electronic)
IS  - 1386-0291 (Linking)
VI  - 75
IP  - 4
DP  - 2020
TI  - Contrast-enhanced ultrasound (CEUS) of cystic renal lesions in comparison to CT 
      and MRI in a multicenter setting.
PG  - 419-429
LID - 10.3233/CH-190764 [doi]
AB  - PURPOSE: Contrast-enhanced-ultrasound (CEUS) has been frequently used in 
      assessment of cystic renal lesions. OBJECTIVE: The aim of this study was to 
      investigate the Bosniak classification in CEUS compared to CT and MRI in a 
      multi-center setting. METHODS: Bosniak classification in CEUS examinations of 
      cystic renal lesions were compared to imaging findings in computed-tomography 
      (ceCT) and magnetic-resonance-imaging (ceMRI). Imaging results were correlated to 
      histopathological reports. All examinations were performed by experts (EFSUMB 
      level 3) using up-to-date CEUS examination-protocols. RESULTS: Overall, 173 
      cystic renal lesions were compared to subgroups CT (n = 87) and MRI (n = 86). 
      Using Bosniak-classification 64/87 renal cysts (73.6%) were rated equal compared 
      to CT with upgrade of four lesions (4.6%) and downgrade of 19 lesions (21.8%) by 
      CT (Intra-class-correlation [ICC] coefficient of 0.824 [p < 0.001]). CEUS 
      compared to MRI, presenting different scoring especially in classes Bosniak IIF 
      (n = 16/31) and Bosniak III (n = 16/28) with an ICC coefficient of 0.651 
      (p < 0.001). CONCLUSION: CEUS can visualize even finest septal and small nodular 
      wall enhancement, which may result in an upgrade of cystic lesions into a higher 
      Bosniak class compared to CT or MRI. Thus, a modification of the Bosniak 
      classification on CEUS may reduce unnecessary biopsies and surgery.
FAU - Lerchbaumer, Markus Herbert
AU  - Lerchbaumer MH
AD  - Charite - Universitatsmedizin Berlin, Corporate Member of FreieUniversitat 
      Berlin, Humbold, Universitatzu Berlin, and Berlin Institute of Health, Department 
      of Radiology, Berlin, Germany.
FAU - Putz, Franz Josef
AU  - Putz FJ
AD  - Department of Nephrology, University Hospital Regensburg, Regensburg, Germany.
FAU - Rubenthaler, Johannes
AU  - Rubenthaler J
AD  - Department of Radiology, Ludwig-Maximilians-University of Munich, Munich, 
      Germany.
FAU - Rogasch, Julian
AU  - Rogasch J
AD  - Charite - Universitatsmedizin Berlin, Corporate Member of FreieUniversitat 
      Berlin, Humbold, Universitatzu Berlin, and Berlin Institute of Health, Department 
      of Nuclear Medicine, Berlin, Germany.
FAU - Jung, Ernst-Michael
AU  - Jung EM
AD  - Department of Radiology, University Medical Center Regensburg, Regensburg, 
      Germany.
FAU - Clevert, Dirk-Andre
AU  - Clevert DA
AD  - Department of Radiology, Ludwig-Maximilians-University of Munich, Munich, 
      Germany.
FAU - Hamm, Bernd
AU  - Hamm B
AD  - Charite - Universitatsmedizin Berlin, Corporate Member of FreieUniversitat 
      Berlin, Humbold, Universitatzu Berlin, and Berlin Institute of Health, Department 
      of Radiology, Berlin, Germany.
FAU - Makowski, Marcus
AU  - Makowski M
AD  - Charite - Universitatsmedizin Berlin, Corporate Member of FreieUniversitat 
      Berlin, Humbold, Universitatzu Berlin, and Berlin Institute of Health, Department 
      of Radiology, Berlin, Germany.
FAU - Fischer, Thomas
AU  - Fischer T
AD  - Charite - Universitatsmedizin Berlin, Corporate Member of FreieUniversitat 
      Berlin, Humbold, Universitatzu Berlin, and Berlin Institute of Health, Department 
      of Radiology, Berlin, Germany.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PL  - Netherlands
TA  - Clin Hemorheol Microcirc
JT  - Clinical hemorheology and microcirculation
JID - 9709206
RN  - 0 (Contrast Media)
SB  - IM
MH  - Aged
MH  - Contrast Media/*therapeutic use
MH  - Female
MH  - Humans
MH  - Kidney/*diagnostic imaging/pathology
MH  - Kidney Diseases, Cystic/*diagnostic imaging/pathology
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Middle Aged
MH  - Tomography, X-Ray Computed/*methods
MH  - Ultrasonography/*methods
OTO - NOTNLM
OT  - Bosniak
OT  - CEUS
OT  - Contrast-enhanced ultrasound
OT  - renal cyst
EDAT- 2020/02/11 06:00
MHDA- 2020/11/11 06:00
CRDT- 2020/02/11 06:00
PHST- 2020/02/11 06:00 [pubmed]
PHST- 2020/11/11 06:00 [medline]
PHST- 2020/02/11 06:00 [entrez]
AID - CH190764 [pii]
AID - 10.3233/CH-190764 [doi]
PST - ppublish
SO  - Clin Hemorheol Microcirc. 2020;75(4):419-429. doi: 10.3233/CH-190764.