PMID- 32043249
OWN - NLM
STAT- MEDLINE
DCOM- 20200710
LR  - 20210110
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 27
IP  - 12
DP  - 2020 Apr
TI  - Hematological parameters and hair mercury levels in adolescents from the 
      Colombian Caribbean.
PG  - 14216-14227
LID - 10.1007/s11356-020-07738-z [doi]
AB  - Mercury (Hg) is one of the heavy metals of concern for fish-eating populations. 
      This pollutant can be released from many sources and generates diverse toxic 
      effects in humans. The aim of this study was to evaluate hematological parameters 
      and their relationship with total Hg (T-Hg) levels in the hair of adolescents 
      from Tierrabomba, an island close to an industrialized area, and also from San 
      Onofre, a reference site. Blood and hair samples were collected from 194 
      individuals, aged 11-18 years old, as well as sociodemographic and dietary 
      information. The hematological profile showed marked differences between the two 
      sites. Mean values for almost all variables of the red blood cell line, as well 
      as lymphocyte percentage (LYM%) and monocyte percentage (MID%), were greater in 
      Tierrabomba. In contrast, red cell distribution width (RDW), white blood cells 
      (WBC), granulocyte percentage (GRA%), and plateletcrit (PTC) were higher at the 
      reference site. Total Hg mean in Tierrabomba was 1.10 +/- 0.07 mug/g, while at San 
      Onofre, it was 1.87 +/- 0.11 mug/g. In both places, more than 49% of participants 
      had Hg concentrations over the limit threshold (1 mug/g). Overall mean corpuscular 
      hemoglobin concentration (MCHC) and T-Hg showed a negative correlation 
      (r = - 0.162, p = 0.024). However, positive associations were observed between 
      T-Hg and MID% for Tierrabomba (r = 0.193, p = 0.041), and between T-Hg and mixed 
      cells (MID) for the reference site (r = 0.223, p = 0.044). A significant 
      relationship was found for fish consumption frequency and T-Hg levels (r = 0.360, 
      p < 0.001). These results indicate blood parameters may be affected by Hg even at 
      low-level exposure.
FAU - Manjarres-Suarez, Alejandra
AU  - Manjarres-Suarez A
AD  - Environmental and Computational Chemistry Group, School of Pharmaceutical 
      Sciences, Zaragocilla Campus, University of Cartagena, Cartagena, 130015, 
      Colombia.
FAU - Olivero-Verbel, Jesus
AU  - Olivero-Verbel J
AUID- ORCID: 0000-0003-3089-5872
AD  - Environmental and Computational Chemistry Group, School of Pharmaceutical 
      Sciences, Zaragocilla Campus, University of Cartagena, Cartagena, 130015, 
      Colombia. joliverov@unicartagena.edu.co.
LA  - eng
GR  - Grant 110777757883, 778/2017/Colciencias/
GR  - 727, 2015/Colciencias/
PT  - Journal Article
DEP - 20200210
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - FXS1BY2PGL (Mercury)
SB  - IM
MH  - Adolescent
MH  - Animals
MH  - Caribbean Region
MH  - Child
MH  - Colombia
MH  - Environmental Exposure/analysis
MH  - Environmental Monitoring
MH  - Fishes
MH  - Food Contamination/analysis
MH  - Hair/chemistry
MH  - Humans
MH  - Mercury/*analysis
OTO - NOTNLM
OT  - Biomarker
OT  - Blood cell lines
OT  - Fish consumption
OT  - Heavy metal
OT  - Human health
OT  - Mercury exposure
EDAT- 2020/02/12 06:00
MHDA- 2020/07/11 06:00
CRDT- 2020/02/12 06:00
PHST- 2019/10/09 00:00 [received]
PHST- 2020/01/14 00:00 [accepted]
PHST- 2020/02/12 06:00 [pubmed]
PHST- 2020/07/11 06:00 [medline]
PHST- 2020/02/12 06:00 [entrez]
AID - 10.1007/s11356-020-07738-z [pii]
AID - 10.1007/s11356-020-07738-z [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2020 Apr;27(12):14216-14227. doi: 
      10.1007/s11356-020-07738-z. Epub 2020 Feb 10.