PMID- 32047846
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2373-8731 (Print)
IS  - 2373-8731 (Electronic)
IS  - 2373-8731 (Linking)
VI  - 6
IP  - 1
DP  - 2020 Jan
TI  - Octreotide Delaying the Progression of Recurrent IgA Nephropathy After Kidney 
      Transplantation.
PG  - e518
LID - 10.1097/TXD.0000000000000963 [doi]
LID - e518
AB  - IgA Nephropathy (IgAN) is a common cause of end-stage kidney disease worldwide. 
      Unfortunately, the exact pathogenesis of IgAN remains uncertain without any 
      targeted therapy. While kidney transplantation remains the gold standard 
      treatment for those with end-stage kidney disease from IgAN, recurrence occurs 
      frequently and may lead to early kidney transplant loss. Research has suggested 
      that insulin-like growth factor-1 may play a role in mesangial cell proliferation 
      in IgAN and Somatostatin may inhibit insulin-like growth factor-1. In this single 
      case study, we report the use of octreotide, a somatostatin analogue, as a 
      potential novel therapy for early recurrent IgAN post kidney transplant.
CI  - Copyright (c) 2019 The Author(s). Transplantation Direct. Published by Wolters 
      Kluwer Health, Inc.
FAU - Sharma, Akhil
AU  - Sharma A
AD  - Department of Medicine and Surgery, University of Pittsburgh Medical Center, 
      Pittsburgh, PA.
FAU - Hariharan, Sundaram
AU  - Hariharan S
AD  - Department of Medicine and Surgery, University of Pittsburgh Medical Center, 
      Pittsburgh, PA.
LA  - eng
GR  - T32 DK061296/DK/NIDDK NIH HHS/United States
PT  - Journal Article
DEP - 20191224
PL  - United States
TA  - Transplant Direct
JT  - Transplantation direct
JID - 101651609
PMC - PMC6964927
EDAT- 2020/02/13 06:00
MHDA- 2020/02/13 06:01
PMCR- 2019/12/24
CRDT- 2020/02/13 06:00
PHST- 2019/09/16 00:00 [received]
PHST- 2019/10/23 00:00 [revised]
PHST- 2019/11/08 00:00 [accepted]
PHST- 2020/02/13 06:00 [entrez]
PHST- 2020/02/13 06:00 [pubmed]
PHST- 2020/02/13 06:01 [medline]
PHST- 2019/12/24 00:00 [pmc-release]
AID - 10.1097/TXD.0000000000000963 [doi]
PST - epublish
SO  - Transplant Direct. 2019 Dec 24;6(1):e518. doi: 10.1097/TXD.0000000000000963. 
      eCollection 2020 Jan.