PMID- 32048345
OWN - NLM
STAT- MEDLINE
DCOM- 20200928
LR  - 20200928
IS  - 1540-8191 (Electronic)
IS  - 0886-0440 (Linking)
VI  - 35
IP  - 4
DP  - 2020 Apr
TI  - Left and right ventricular function detection and myocardial deformation analysis 
      in heart transplant patients with long-time follow-ups.
PG  - 755-763
LID - 10.1111/jocs.14461 [doi]
AB  - OBJECTIVE: We try to investigate whether the values of longitudinal strain 
      present differences between the left and right ventricles in long-time follow-ups 
      after heart transplantation (HTx) with dynamic changes in function. METHODS AND 
      RESULTS: Follow-up transthoracic echocardiography was performed in 1- and 3-month 
      and 1- and 5-year follow-ups in 50 "healthy" HTx patients and compared with 26 
      control subjects. The left ventricle with preserved ejection fraction evaluated 
      by biplane Simpson (control group [CG] vs HT; P > .05) had an obvious reduction 
      in global (CG: -20.49 +/- 2.38 vs heart transplant 1 month [HT1m]: -13.06 +/- 2.86, 
      heart transplant 3 month [HT3m]: -13.61 +/- 2.61, heart transplant 1 year [HT1y]: 
      -13.69 +/- 4.56, heart transplant 5 year [HT5y]: -14.41 +/- 4.54; P < .001) and 
      horizontal segmental (basal, mid, apical) (P < .001) together with chamber 
      segmental (apical 4-chamber, apical 3-chamber, apical 2-chamber) (P < .001) 
      average strain values. The right ventricle with reduced ventricular function 
      measured by tissue Doppler imaging S' and tricuspid annular plane systolic 
      excursion had a more distinctive reduction in global (CG: -24.53 +/- 4.20 vs HT1m: 
      -12.94 +/- 5.03, HT3m: -13.68 +/- 4.35, HT1y: -14.95 +/- 7.50, HT5y: -15.20 +/- 6.15; 
      P < .001) with segmental lateral (P < .001) strain values. There were not any 
      significant changes between 1- and 3-month follow-ups of all the values 
      (P > .05). But it could be seen that values increased in 1- and 5-year follow-ups 
      compared with the baseline of 1- and 3-month follow-ups (P < .05). The global and 
      segmental strain of the right ventricle decreased more than that of the left 
      ventricle in all HTx groups, and the strain values were decreased in the HTx 
      groups compared with the CG, with the global decreased change rates being 11%, 
      10%, 6%, and 8%, respectively. CONCLUSIONS: The strain values decreased after HTx 
      and almost remained stable in the long-time follow-ups. Compared with the CG in 
      both ventricles, they were with preserved or reduced functions. In addition, the 
      deformation values of the right ventricle decreased more than those of the left.
CI  - (c) 2020 Wiley Periodicals, Inc.
FAU - Ran, Hong
AU  - Ran H
AUID- ORCID: 0000-0002-2587-3348
AD  - Department of Echocardiography, Nanjing First Hospital, Nanjing Medical 
      University, Nanjing, Jiangsu, China.
FAU - Zhang, Ping-Yang
AU  - Zhang PY
AD  - Department of Echocardiography, Nanjing First Hospital, Nanjing Medical 
      University, Nanjing, Jiangsu, China.
FAU - Ma, Xiao-Wu
AU  - Ma XW
AD  - Department of Echocardiography, Nanjing First Hospital, Nanjing Medical 
      University, Nanjing, Jiangsu, China.
FAU - Dong, Jing
AU  - Dong J
AD  - Department of Echocardiography, Nanjing First Hospital, Nanjing Medical 
      University, Nanjing, Jiangsu, China.
FAU - Wu, Wen-Fang
AU  - Wu WF
AD  - Department of Echocardiography, Nanjing First Hospital, Nanjing Medical 
      University, Nanjing, Jiangsu, China.
LA  - eng
GR  - 2017(8)/Nanjing Medical Science and Technique Development Foundation/
PT  - Journal Article
DEP - 20200212
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
MH  - Adult
MH  - Aged
MH  - Cohort Studies
MH  - Echocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Heart/diagnostic imaging/*physiology
MH  - Heart Failure/diagnostic imaging/*physiopathology/*surgery
MH  - *Heart Transplantation
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - *Stroke Volume
MH  - Time Factors
MH  - *Ventricular Function, Left
MH  - *Ventricular Function, Right
OTO - NOTNLM
OT  - echocardiography
OT  - follow-up
OT  - heart transplantation
OT  - longitudinal strain
EDAT- 2020/02/13 06:00
MHDA- 2020/09/29 06:00
CRDT- 2020/02/13 06:00
PHST- 2020/02/13 06:00 [pubmed]
PHST- 2020/09/29 06:00 [medline]
PHST- 2020/02/13 06:00 [entrez]
AID - 10.1111/jocs.14461 [doi]
PST - ppublish
SO  - J Card Surg. 2020 Apr;35(4):755-763. doi: 10.1111/jocs.14461. Epub 2020 Feb 12.