PMID- 32051763
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220412
IS  - 2090-004X (Print)
IS  - 2090-0058 (Electronic)
IS  - 2090-004X (Linking)
VI  - 2020
DP  - 2020
TI  - Polypoidal Choroidal Vasculopathy in Congolese Patients.
PG  - 4103871
LID - 10.1155/2020/4103871 [doi]
LID - 4103871
AB  - PURPOSE: Polypoidal choroidal vasculopathy (PCV) is a visually debilitating 
      disease that mostly affects people of African and Asian heritage. Indocyanine 
      green angiography (ICGA) is the recommended exploratory method for definitive 
      diagnosis. The disease has been extensively described in Asians and Caucasians, 
      but not in Africans. This study was conducted to document the clinical 
      presentation and optical coherence tomography features of polypoidal choroidal 
      vasculopathy (PCV) in Congolese patients. METHODS: A prospective case series of 
      patients with PCV was performed between January 2017 and June 2019. Routine 
      ocular examination was performed including best corrected visual acuity 
      measurement, slit-lamp examination, dilated direct fundoscopy, and spectral 
      domain optical coherence tomography (OCT). The diagnosis was based on a 
      combination of clinical and OCT signs. RESULTS: Fourteen patients were diagnosed 
      with PCV during this period. The average age was 64.7 +/- 6.9 years. There were 8 
      females. Ten (71.4%) patients had systemic hypertension. Most patients (n = 9, 
      64.3%) had bilateral involvement. Blurred vision was the most common complaint 
      (71.4%). The main clinical presentation was subretinal exudates, seen in 19 
      (82.6%) eyes of 11 (78.6%) patients and subretinal hemorrhage in 10 (43.5%) eyes. 
      Macular localization was found in 16 eyes (69.5%) of 12 (85.7%) patients. Drusen 
      were observed in 35.7% of the patients. On OCT imaging, thumb-like pigment 
      epithelial detachment and subretinal exudation were the most frequent features, 
      observed in 92.9% and 71.4% of the patients, respectively. CONCLUSIONS: PCV in 
      Congolese patients showed features that are more similar to those observed in 
      Caucasians. In this setting where indocyanine green angiography is not available, 
      OCT facilitates the diagnosis of PCV.
CI  - Copyright (c) 2020 Nelly N. Kabedi et al.
FAU - Kabedi, Nelly N
AU  - Kabedi NN
AUID- ORCID: 0000-0001-5118-3861
AD  - Department of Ophthalmology, School of Medicine, University of Kinshasa, 
      Kinshasa, Democratic Republic of the Congo.
FAU - Kayembe, David L
AU  - Kayembe DL
AD  - Department of Ophthalmology, School of Medicine, University of Kinshasa, 
      Kinshasa, Democratic Republic of the Congo.
FAU - Elongo, Gloria M
AU  - Elongo GM
AD  - Department of Ophthalmology, School of Medicine, University of Kinshasa, 
      Kinshasa, Democratic Republic of the Congo.
FAU - Mwanza, Jean-Claude
AU  - Mwanza JC
AUID- ORCID: 0000-0002-2346-5885
AD  - Department of Ophthalmology, School of Medicine, University of Kinshasa, 
      Kinshasa, Democratic Republic of the Congo.
AD  - Department of Ophthalmology, School of Medicine, University of North Carolina at 
      Chapel Hill, Chapel Hill, North Carolina, USA.
LA  - eng
PT  - Journal Article
DEP - 20200118
PL  - United States
TA  - J Ophthalmol
JT  - Journal of ophthalmology
JID - 101524199
PMC - PMC6995324
COIS- The authors declare no conflicts of interest regarding this article.
EDAT- 2020/02/14 06:00
MHDA- 2020/02/14 06:01
PMCR- 2020/01/18
CRDT- 2020/02/14 06:00
PHST- 2019/10/03 00:00 [received]
PHST- 2019/12/21 00:00 [accepted]
PHST- 2020/02/14 06:00 [entrez]
PHST- 2020/02/14 06:00 [pubmed]
PHST- 2020/02/14 06:01 [medline]
PHST- 2020/01/18 00:00 [pmc-release]
AID - 10.1155/2020/4103871 [doi]
PST - epublish
SO  - J Ophthalmol. 2020 Jan 18;2020:4103871. doi: 10.1155/2020/4103871. eCollection 
      2020.