PMID- 32052111
OWN - NLM
STAT- MEDLINE
DCOM- 20200917
LR  - 20200917
IS  - 1433-0385 (Electronic)
IS  - 0009-4722 (Linking)
VI  - 91
IP  - 6
DP  - 2020 Jun
TI  - [Intraoperative measurement of parathyroid hormone in hyperparathyroidism].
PG  - 448-455
LID - 10.1007/s00104-020-01123-9 [doi]
AB  - Intraoperative parathyroid hormone (IOPTH) determination is based on the short 
      half-life of parathyroid hormone (PTH) and the rapid analytical technology. The 
      IOPTH provides functional information regarding correction of the overproductive 
      state in hyperparathyroidism (HPT) and is superior to macroscopic evaluation of 
      the parathyroid gland (PG) as well as any (intraoperative frozen section) form of 
      histology (so-called biochemical frozen section). In this article the relevance 
      and evaluation of IOPTH is defined for the most important forms of HPT, for 
      primary HPT, renal secondary and tertiary HPT, multiple endocrine neoplasia type 
      1 (MEN1) and parathyroid carcinoma and clinical scenarios based on the currently 
      available data. It becomes apparent that the additional benefits of IOPTH depend 
      on diverse prerequisites of the specific type of HPT, the diagnostics as well as 
      individual patient factors and strategic considerations for resection. Overall, 
      the costs for IOPTH are comparably low and seem to be justified with respect to 
      the gain in quality. In the hands of specialized endocrine surgeons IOPTH is an 
      essential tool for intraoperative decision-making and quality assurance.
FAU - Lorenz, K
AU  - Lorenz K
AD  - Klinik fur Viszeral‑, Gefass- und Endokrine Chirurgie, Universitatsklinikum Halle, 
      Martin-Luther Universitat Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle 
      an der Saale, Deutschland. kerstin.lorenz@uk-halle.de.
FAU - Schneider, R
AU  - Schneider R
AD  - Klinik fur Viszeral‑, Gefass- und Endokrine Chirurgie, Universitatsklinikum Halle, 
      Martin-Luther Universitat Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle 
      an der Saale, Deutschland.
FAU - Elwerr, M
AU  - Elwerr M
AD  - Klinik fur Viszeral‑, Gefass- und Endokrine Chirurgie, Universitatsklinikum Halle, 
      Martin-Luther Universitat Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle 
      an der Saale, Deutschland.
LA  - ger
PT  - Journal Article
PT  - Review
TT  - Intraoperative Parathormonmessung bei Hyperparathyreoidismus.
PL  - Germany
TA  - Chirurg
JT  - Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen
JID - 16140410R
RN  - 0 (Parathyroid Hormone)
SB  - IM
MH  - Humans
MH  - Hyperparathyroidism, Primary/*surgery
MH  - Monitoring, Intraoperative
MH  - *Parathyroid Hormone
MH  - Parathyroidectomy
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Biochemical frozen section
OT  - MEN1
OT  - Parathyroid carcinoma
OT  - Success criteria
OT  - Surgical strategy
EDAT- 2020/02/14 06:00
MHDA- 2020/09/18 06:00
CRDT- 2020/02/14 06:00
PHST- 2020/02/14 06:00 [pubmed]
PHST- 2020/09/18 06:00 [medline]
PHST- 2020/02/14 06:00 [entrez]
AID - 10.1007/s00104-020-01123-9 [pii]
AID - 10.1007/s00104-020-01123-9 [doi]
PST - ppublish
SO  - Chirurg. 2020 Jun;91(6):448-455. doi: 10.1007/s00104-020-01123-9.