PMID- 32061619 OWN - NLM STAT- MEDLINE DCOM- 20210528 LR - 20210528 IS - 1872-7492 (Electronic) IS - 0168-1702 (Linking) VI - 280 DP - 2020 Apr 15 TI - The NC229 multi-station research consortium on emerging viral diseases of swine: Solving stakeholder problems through innovative science and research. PG - 197898 LID - S0168-1702(19)30872-X [pii] LID - 10.1016/j.virusres.2020.197898 [doi] AB - The NC229 research consortium was created in 1999 in response to the emergence of porcine reproductive and respiratory syndrome virus (PRRSV), a viral agent responsible for devastating economic losses to the swine industry. The project follows the traditional "consortium" approach for Multistate Agricultural Research driven through the US State Agricultural Experiment Stations (SAES), wherein stakeholder-driven needs to combat swine infectious diseases are identified and scientific solutions pursued by combining funds from federal, state, commodity groups, and the animal health industry. The NC229 consortium was the main driving force in successfully competing for a USDA multi-station Coordinated Agricultural Project (PRRS CAP-I) in 2004-2008, immediately followed by a renewal for 2010-2014 (PRRS CAP-II)-, resulting in an overall record achievement of almost $10 million dollars. The CAP funding was not only useful for quality research, extension, and education in PRRS and related diseases, but also instrumental in enabling the group to leverage swine industry funding of more than $34 million dollars, distributed between creative research and extension on PRRS during the last 20 years. The North American/International PRRS Symposium, now recognized by the community as a highly effective platform for the exchange of basic research findings and fundamental translational technology, is directly derived from the NC229 consortium. Other significant offshoots from NC229 include the PHGC (PRRS Host Genomic Consortium), a platform for discoveries on the role of host genetics during PRRSV infection, since 2007. Since 2009, the NC229 consortium has expanded its collective research interests beyond PRRSV to include nine other emerging viral diseases of swine. In the current project (2019-2024), African Swine Fever Virus (ASFV) retains a central focus, with the goal of harnessing the group's expertise in promoting preparedness for the global control of ASFV. CI - Copyright (c) 2020 Elsevier B.V. All rights reserved. FAU - Benfield, David AU - Benfield D AD - Ohio Agricultural Experiment Station, The Ohio State University, College of Food, Agricultural, and Environmental Sciences, Wooster, OH, 44691, United States. FAU - Lunney, Joan K AU - Lunney JK AD - Beltsville Agricultural Research Center, Northeast Area, USDA/ARS, Beltsville, MD, 20705, United States. FAU - Murtaugh, Michael AU - Murtaugh M AD - Department of Veterinary Biomedical Sciences, College of Veterinary Medicine, University of Minnesota St. Paul, MN, 55108, United States. FAU - Nelson, Eric AU - Nelson E AD - Animal Disease Research & Diagnostic Laboratory, South Dakota State University, Brookings, SD, 57007, United States. FAU - Osorio, Fernando AU - Osorio F AD - Nebraska Center for Virology and School of Veterinary and Biomedical Sciences University of Nebraska-Lincoln, Lincoln, NE, 68583-0900, United States. Electronic address: fosorio@unl.edu. FAU - Pogranichniy, Roman AU - Pogranichniy R AD - Animal Disease Diagnostic Laboratory, College of Veterinary Medicine Purdue University, West Lafayette, IN, 47907-2065, United States. FAU - Ramamoorthy, Sheela AU - Ramamoorthy S AD - Microbiological Sciences, N. Dakota State University, Fargo, ND, 58108, United States. FAU - Rowland, Raymond R R AU - Rowland RRR AD - Department of Diagnostic Medicine and Pathobiology, College of Veterinary Medicine, Manhattan, KS, 66506, United States. FAU - Zimmerman, Jeffrey J AU - Zimmerman JJ AD - Veterinary Medical Research Institute, College of Veterinary Medicine, Iowa State University, Ames, Iowa, 50011-1240, United States. FAU - Zuckermann, Federico A AU - Zuckermann FA AD - Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, IL, 61802, United States. LA - eng PT - Journal Article PT - Research Support, U.S. Gov't, Non-P.H.S. DEP - 20200228 PL - Netherlands TA - Virus Res JT - Virus research JID - 8410979 SB - IM MH - Animals MH - Communicable Diseases, Emerging/*veterinary/*virology MH - Congresses as Topic MH - Porcine Reproductive and Respiratory Syndrome/prevention & control MH - Porcine respiratory and reproductive syndrome virus/genetics MH - Research/economics/*organization & administration MH - Stakeholder Participation MH - Swine MH - United States MH - Virus Diseases/prevention & control/*veterinary OTO - NOTNLM OT - African swine fever virus OT - Multi-station agricultural research OT - NC229 OT - PRRSV OT - Swine emerging viruses OT - Swine influenza EDAT- 2020/02/18 06:00 MHDA- 2021/05/29 06:00 CRDT- 2020/02/17 06:00 PHST- 2019/12/11 00:00 [received] PHST- 2020/01/22 00:00 [revised] PHST- 2020/02/11 00:00 [accepted] PHST- 2020/02/18 06:00 [pubmed] PHST- 2021/05/29 06:00 [medline] PHST- 2020/02/17 06:00 [entrez] AID - S0168-1702(19)30872-X [pii] AID - 10.1016/j.virusres.2020.197898 [doi] PST - ppublish SO - Virus Res. 2020 Apr 15;280:197898. doi: 10.1016/j.virusres.2020.197898. Epub 2020 Feb 28.