PMID- 32077829
OWN - NLM
STAT- MEDLINE
DCOM- 20210218
LR  - 20211102
IS  - 1875-6557 (Electronic)
IS  - 1573-403X (Print)
IS  - 1573-403X (Linking)
VI  - 16
IP  - 4
DP  - 2020
TI  - Cardiovascular Effects of Metabolic Surgery on Type 2 Diabetes.
PG  - 275-284
LID - 10.2174/1573403X16666200220120226 [doi]
AB  - INTRODUCTION: Cardiovascular, together with renal disease, claims a significant 
      proportion of morbidity and mortality in association with type 2 diabetes 
      mellitus (T2DM) and obesity. To improve the long-term renal and cardiovascular 
      outcome, there is the incorporation of bariatric surgery (BS), which seems to be 
      a pivotal intervention. Areas Explored: Cohort studies and randomized controlled 
      trial (RCT) research of BS among patients with T2DM, were conducted by screening, 
      and then information on renal effects and the cardiovascular outcome was 
      gathered. Metabolic surgery (MS) and BS reduce both mortality and the risk of 
      cardiovascular disorder, chronic kidney diseases and albuminuria. MS refers to a 
      surgical approach, the primary intent of which is the control of metabolic 
      alterations/hyperglycemia in contrast to BS which is a mere weight-reduction 
      therapy. Patients suffering from poor glycaemic control and other macro and 
      micro-vascular diseases will benefit from a surgical approach. The approach 
      implicates hypertension glomerular remission, gut microbiota shift, reduced renal 
      inflammation and fewer instances of chronic cardiac remodelling. CONCLUSION: MS 
      is beneficial where the main aim is to attain significant and long-lasting weight 
      loss results. The RCTs have depicted the superiority which surgical mechanisms 
      hold over medically- based therapy, for enhancing glycaemic control, and 
      achieving remission of diabetes. This type of surgery improves life quality, 
      reduces incidences of other obesity and diabetes related diseases like 
      microvascular disases, sleep apnea, fatal disorder, and fatty liver disease.
CI  - Copyright(c) Bentham Science Publishers; For any queries, please email at 
      epub@benthamscience.net.
FAU - Damaskos, Christos
AU  - Damaskos C
AD  - Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, 
      National and Kapodistrian University of Athens, Athens, Greece.
FAU - Litos, Alexandros
AU  - Litos A
AD  - Psychiatric Department, General Hospital of Athens G. Gennimatas, Athens, Greece.
FAU - Dimitroulis, Dimitrios
AU  - Dimitroulis D
AD  - Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, 
      National and Kapodistrian University of Athens, Athens, Greece.
FAU - Antoniou, Efstathios A
AU  - Antoniou EA
AD  - Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, 
      National and Kapodistrian University of Athens, Athens, Greece.
FAU - Mantas, Dimitrios
AU  - Mantas D
AD  - Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, 
      National and Kapodistrian University of Athens, Athens, Greece.
FAU - Kontzoglou, Konstantinos
AU  - Kontzoglou K
AD  - Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, 
      National and Kapodistrian University of Athens, Athens, Greece.
FAU - Garmpis, Nikolaos
AU  - Garmpis N
AD  - Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, 
      National and Kapodistrian University of Athens, Athens, Greece.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United Arab Emirates
TA  - Curr Cardiol Rev
JT  - Current cardiology reviews
JID - 101261935
SB  - IM
MH  - Bariatric Surgery/*methods
MH  - Cardiovascular Diseases/*surgery
MH  - Cohort Studies
MH  - Diabetes Mellitus, Type 2/*complications/*surgery
MH  - Humans
MH  - Obesity/complications/*surgery
MH  - Weight Loss/*physiology
PMC - PMC7903510
OTO - NOTNLM
OT  - Cardiovascular
OT  - bariatric
OT  - metabolic surgery
OT  - obesity
OT  - procedures
OT  - type 2 diabetes
EDAT- 2020/02/23 06:00
MHDA- 2021/02/20 06:00
PMCR- 2021/11/01
CRDT- 2020/02/21 06:00
PHST- 2018/12/21 00:00 [received]
PHST- 2019/11/29 00:00 [revised]
PHST- 2019/12/18 00:00 [accepted]
PHST- 2020/02/23 06:00 [pubmed]
PHST- 2021/02/20 06:00 [medline]
PHST- 2020/02/21 06:00 [entrez]
PHST- 2021/11/01 00:00 [pmc-release]
AID - CCR-EPUB-104682 [pii]
AID - CCR-16-275 [pii]
AID - 10.2174/1573403X16666200220120226 [doi]
PST - ppublish
SO  - Curr Cardiol Rev. 2020;16(4):275-284. doi: 10.2174/1573403X16666200220120226.