PMID- 32082662
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200928
IS  - 2090-6706 (Print)
IS  - 2090-6714 (Electronic)
VI  - 2020
DP  - 2020
TI  - A Nonpediatric Extraosseous Ewing Sarcoma of the Pancreas: Differential Diagnosis 
      and Therapeutic Strategies.
PG  - 2792750
LID - 10.1155/2020/2792750 [doi]
LID - 2792750
AB  - Extraosseous Ewing's sarcoma is a rare and aggressive malignant tumor with a poor 
      prognosis. The pancreas is an extremely uncommon primary site, with only 27 cases 
      that have been published worldwide. We report a 26-year-old female who presented 
      with 5 days of left upper quadrant pain, nausea, and vomiting. On examination, 
      she was anicteric and had epigastric and left upper quadrant tenderness without 
      guarding, rebound tenderness, or a palpable mass. She had slightly elevated serum 
      aminotransferase and lipase levels. Abdominal computerized tomography revealed a 
      multilobulated tumor arising from the body and tail of the pancreas. A biopsy 
      confirmed a small round cell tumor, and immunohistochemistry was positive for 
      CD99 in approximately 70% of the tumor cells. A fluorescence in situ 
      hybridization (FISH) assay showed a 22q12 rearrangement. She was diagnosed with 
      extraosseous Ewing sarcoma of the pancreas and underwent multiagent neoadjuvant 
      chemotherapy followed by surgical resection, but subsequent imaging revealed 
      evidence of systemic disease progression. She chose to go on hospice care and 
      died a few weeks later.
CI  - Copyright (c) 2020 Binoy Yohannan and Mark Feldman.
FAU - Yohannan, Binoy
AU  - Yohannan B
AUID- ORCID: 0000-0003-0207-329X
AD  - Department of Internal Medicine, Texas Health Presbyterian Hospital Dallas, Texas 
      75231, USA.
FAU - Feldman, Mark
AU  - Feldman M
AUID- ORCID: 0000-0003-4448-3991
AD  - Department of Internal Medicine, Texas Health Presbyterian Hospital Dallas, Texas 
      75231, USA.
LA  - eng
PT  - Case Reports
DEP - 20200130
PL  - United States
TA  - Case Rep Oncol Med
JT  - Case reports in oncological medicine
JID - 101581035
PMC - PMC7013316
COIS- The authors have no conflicting interest.
EDAT- 2020/02/23 06:00
MHDA- 2020/02/23 06:01
PMCR- 2020/01/30
CRDT- 2020/02/22 06:00
PHST- 2019/06/07 00:00 [received]
PHST- 2020/01/10 00:00 [accepted]
PHST- 2020/02/22 06:00 [entrez]
PHST- 2020/02/23 06:00 [pubmed]
PHST- 2020/02/23 06:01 [medline]
PHST- 2020/01/30 00:00 [pmc-release]
AID - 10.1155/2020/2792750 [doi]
PST - epublish
SO  - Case Rep Oncol Med. 2020 Jan 30;2020:2792750. doi: 10.1155/2020/2792750. 
      eCollection 2020.